Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Norman A. Staines"'
Autor:
Loryman B, M E Devey, S M Hobbs, Isaacs Ab, H S Thompson, Norman A. Staines, P J Major, Ekong Ta
The relationship between the functional affinity of antibodies against type II collagen (CII) and the development of arthritis was studied in mice with collagen-induced arthritis. The responses of DBA/1 strain mice were compared with those of mice se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f4711f46d0cadf7179a92249bec311
https://ora.ox.ac.uk/objects/uuid:0c3ebb15-25a8-418c-a3ce-703e4a5d172e
https://ora.ox.ac.uk/objects/uuid:0c3ebb15-25a8-418c-a3ce-703e4a5d172e
Constraints on the Efficacy of Mucosal Tolerance in Treatment of Human and Animal Arthritic Diseases
Autor:
Norman A. Staines, Lilia Marinova‐Mutafchieva, John J. Murphy, Catherine J. Derry, D. Huw Davies, Nadira Ali
Publikováno v:
Annals of the New York Academy of Sciences. 1029:250-259
Mucosal administration of an autoantigen has been shown to be a powerful way of inducing tolerance in both animal and human arthritis clinical trials. Bovine or chicken type II collagen has been administered orally to rheumatoid arthritis patients, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd02c6a597dcf4cb5900424ce23d240
https://doi.org/10.1196/annals.1309.056
https://doi.org/10.1196/annals.1309.056
Publikováno v:
Lupus, 11, 793-6
Lupus, 11, 12, pp. 793-6
Lupus, 11, 12, pp. 793-6
Item does not contain fulltext Our increased understanding of the pathogenesis of systemic lupus erythematosus is leading to new ideas about its therapy. In this session of the workshop the use of LJP 394 a B cell toleragen and the use of an anti-CD2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cdb60d5f220483ac5cb3bd767e291c3
https://doi.org/10.1191/0961203302lu320oa
https://doi.org/10.1191/0961203302lu320oa
Autor:
Paul H. Wooley, Jerry S. Lanchbury, R. van der Zee, M D Bodman-Smith, Darryl J. Pappin, C Soh, Gabriel S. Panayi, Suzanne E. Berlo, Valerie Corrigall, Linda K. Myers, M S Fife, Norman A. Staines, W. van Eden, Benito Cañas
Publikováno v:
The Journal of Immunology. 166:1492-1498
Rheumatoid arthritis (RA) is the most common, crippling human autoimmune disease. Using Western blotting and tandem mass spectroscopy, we have identified the endoplasmic reticulum chaperone BiP, a 78-kDa glucose-regulated protein, as a possible autoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f23c50a0b7471fad3a4ec980b86747
https://doi.org/10.4049/jimmunol.166.3.1492
https://doi.org/10.4049/jimmunol.166.3.1492
Autor:
David Scott, Ernest Choy, Norman A. Staines, Gabrielle Kingsley, A G Murphy, Gabriel S. Panayi, S Thomas
Publikováno v:
Arthritis & Rheumatism. 44:1993-1997
Objective Previous randomized controlled trials for treatment of rheumatoid arthritis (RA) with acid-soluble chicken and bovine type II collagen (CII) have produced conflicting results. This randomized, double-blind, controlled trial examined the the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89754db924e8b7a80bb94a5fe743cbd7
https://doi.org/10.1002/1529-0131(200109)44:9<1993::aid-art347>3.0.co
https://doi.org/10.1002/1529-0131(200109)44:9<1993::aid-art347>3.0.co
Publikováno v:
Arthritis & Rheumatism. 44:1917-1927
Objective To determine the influence of the dose of collagen given nasally on the induction of specific mucosal tolerance in collagen-induced arthritis. Methods The severity of clinical arthritis induced in DBA/1 mice was studied after the nasal admi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b76987125275cc1e98cf8ce9029d5de
https://doi.org/10.1002/1529-0131(200108)44:8<1917::aid-art330>3.0.co
https://doi.org/10.1002/1529-0131(200108)44:8<1917::aid-art330>3.0.co
Publikováno v:
Immunology. 101:371-377
The origin and relative biological importance of the many different DNA-reactive antibodies that appear in systemic lupus erythematosus are not well understood. A detailed analysis of their fine specificity and binding characteristics with DNA is a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d466bfdd7c528554a2cd0ff7c1ed71f
https://doi.org/10.1046/j.1365-2567.2000.00119.x
https://doi.org/10.1046/j.1365-2567.2000.00119.x
Autor:
Ana Nóvoa, Norman A. Staines, Celso Cunha, Elsa Bronze-da-Rocha, Claudio E. Sunkel, Maria Carmo-Fonseca
Publikováno v:
Chromosome Research. 8:699-711
Metaphase chromosome protein 1 (MCP1) is a nuclear autoantigen that is associated with condensed chromosomes throughout mitosis. During interphase, this antigen shows a speckle distribution in the nucleus, excluding the nucleolus. Additionally, MCP1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1fef0b850d9ef4a7241d8aa614a2a63
https://doi.org/10.1023/a:1012097704355
https://doi.org/10.1023/a:1012097704355
Autor:
Paul Hobby, Francis J. Ward, Andrew N. Denbury, D. Gwyn Williams, Norman A. Staines, Brian J. Sutton
Publikováno v:
The Journal of Immunology. 161:2944-2952
Anti-DNA autoantibodies are a characteristic feature of human systemic lupus erythematosus (SLE) and lupus diseases in the mouse. V-88 is an IgG1/κ ssDNA-binding Ab, derived from a lupus mouse, that bears a cross-species, cross-reactive Id (CRI) tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b32b245dd4893671834767501accf58c
https://doi.org/10.4049/jimmunol.161.6.2944
https://doi.org/10.4049/jimmunol.161.6.2944
Autor:
Jerrie Gavalchin, Norman A. Staines
Publikováno v:
Lupus. 6:337-343
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66fbcc7849040a31422cae75b414b8e
https://doi.org/10.1177/096120339700600331
https://doi.org/10.1177/096120339700600331