Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Norman Koglin"'
Autor:
Beth Whittington, Evangelos Tzolos, Shruti Joshi, Rong Bing, Jack Andrews, Krithika Loganath, Neil Craig, Craig Balmforth, Laura Clark, Christophe Lucatelli, Mark G MacAskill, Adriana A. S. Tavares, Tim Clark, Nicholas L. Mills, Jennifer Nash, Damini Dey, Piotr J. Slomka, Norman Koglin, Andrew W. Stephens, Marc R. Dweck, Michelle C. Williams, William Whiteley, Edwin J. R. van Beek, Joanna M. Wardlaw, David E. Newby
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract 18F-GP1 is a novel highly specific radiotracer that binds to activated platelets and thrombus. We aimed to establish the observer repeatability of coronary, carotid and cerebral 18F-GP1 uptake in patients presenting with acute myocardial inf
Externí odkaz:
https://doaj.org/article/194b1bf42855456291d6ae2505b2b1c3
Autor:
Anna Ballweg, Carolin Klaus, Letizia Vogler, Sabrina Katzdobler, Karin Wind, Artem Zatcepin, Sibylle I. Ziegler, Birkan Secgin, Florian Eckenweber, Bernd Bohr, Alexander Bernhardt, Urban Fietzek, Boris-Stephan Rauchmann, Sophia Stoecklein, Stefanie Quach, Leonie Beyer, Maximilian Scheifele, Marcel Simmet, Emanuel Joseph, Simon Lindner, Isabella Berg, Norman Koglin, Andre Mueller, Andrew W. Stephens, Peter Bartenstein, Joerg C. Tonn, Nathalie L. Albert, Tania Kümpfel, Martin Kerschensteiner, Robert Perneczky, Johannes Levin, Lars Paeger, Jochen Herms, Matthias Brendel
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Objectives Reactive gliosis is a common pathological hallmark of CNS pathology resulting from neurodegeneration and neuroinflammation. In this study we investigate the capability of a novel monoamine oxidase B (MAO-B) PET ligand to monitor r
Externí odkaz:
https://doaj.org/article/497126e6fe484a14b58f292c7979ad26
Autor:
Santiago Bullich, Andre Mueller, Susan De Santi, Norman Koglin, Stephen Krause, June Kaplow, Michio Kanekiyo, Núria Roé-Vellvé, Audrey Perrotin, Aleksandar Jovalekic, David Scott, Michelle Gee, Andrew Stephens, Michael Irizarry
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background The ability of 18F-PI-2620 PET to measure the spatial distribution of tau pathology in Alzheimer’s disease (AD) has been demonstrated in previous studies. The objective of this work was to evaluate tau deposition using 18F-PI-26
Externí odkaz:
https://doaj.org/article/8e77b5cba44a4f58a7c6388004ac5e5a
Autor:
Santiago Bullich, Núria Roé-Vellvé, Marta Marquié, Susan M. Landau, Henryk Barthel, Victor L. Villemagne, Ángela Sanabria, Juan Pablo Tartari, Oscar Sotolongo-Grau, Vincent Doré, Norman Koglin, Andre Müller, Audrey Perrotin, Aleksandar Jovalekic, Susan De Santi, Lluís Tárraga, Andrew W. Stephens, Christopher C. Rowe, Osama Sabri, John P. Seibyl, Mercè Boada
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2021)
Abstract Background A low amount and extent of Aβ deposition at early stages of Alzheimer’s disease (AD) may limit the use of previously developed pathology-proven composite SUVR cutoffs. This study aims to characterize the population with earlies
Externí odkaz:
https://doaj.org/article/6b3f6777c03f4d5e85d5f200936af1eb
Autor:
Sonya Y. Park, Camila Mosci, Meena Kumar, Mirwais Wardak, Norman Koglin, Santiago Bullich, Andre Mueller, Mathias Berndt, Andrew W. Stephens, Frederick T. Chin, Sanjiv S. Gambhir, Erik S. Mittra
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Purpose (4S)-4-(3-[18F]Fluoropropyl)-l-glutamic acid ([18F]FSPG) measures system xC − transporter activity and shows promise for oncologic imaging. We present data on tumor uptake of this radiopharmaceutical in human subjects with head and
Externí odkaz:
https://doaj.org/article/97f3df152e174153b67cf1d6636b932f
Autor:
Marie Willroider, Sigrun Roeber, Anja K. E. Horn, Thomas Arzberger, Maximilian Scheifele, Gesine Respondek, Osama Sabri, Henryk Barthel, Marianne Patt, Olena Mishchenko, Andreas Schildan, André Mueller, Norman Koglin, Andrew Stephens, Johannes Levin, Günter U. Höglinger, Peter Bartenstein, Jochen Herms, Matthias Brendel, Leonie Beyer
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objectives: Autoradiography on brain tissue is used to validate binding targets of newly discovered radiotracers. The purpose of this study was to correlate quantification of autoradiography signal using the novel next-generation tau positron emissio
Externí odkaz:
https://doaj.org/article/204039db83664a75824cf7da9c040999
Autor:
Sun Young Chae, Tae-Won Kwon, Soyoung Jin, Sun U. Kwon, Changhwan Sung, Seung Jun Oh, Sang Ju Lee, Jungsu S. Oh, Youngjin Han, Yong-Pil Cho, Narae Lee, Ji Young Kim, Norman Koglin, Mathias Berndt, Andrew W. Stephens, Dae Hyuk Moon
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Background 18F-GP1 is a novel positron emission tomography (PET) tracer that targets glycoprotein IIb/IIIa receptors on activated platelets. The study objective was to explore the feasibility of directly imaging acute arterial thrombosis (AA
Externí odkaz:
https://doaj.org/article/80a98819709443d68bdf857a867bd57f
Autor:
Verena Hugenberg, Marion Zerna, Mathias Berndt, Reinhard Zabel, Rainer Preuss, Dirk Rolfsmeier, Janet Wegener, Henrik Fox, Astrid Kassner, Hendrik Milting, Norman Koglin, Andrew W. Stephens, Jan F. Gummert, Wolfgang Burchert, Marcus-André Deutsch
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 739 (2021)
Thrombus formation and thromboembolic events play important roles in various cardiovascular pathologies. The key receptor involved in platelet aggregation is the fibrinogen receptor glycoprotein IIb/IIIa. [18F]GP1, a derivative of the GPIIb/IIIa anta
Externí odkaz:
https://doaj.org/article/da912480adb4441386fc01f3701bd89b
Autor:
Santiago Bullich, John Seibyl, Ana M. Catafau, Aleksandar Jovalekic, Norman Koglin, Henryk Barthel, Osama Sabri, Susan De Santi
Publikováno v:
NeuroImage: Clinical, Vol 15, Iss , Pp 325-332 (2017)
Introduction: Standardized uptake value ratios (SUVRs) calculated from cerebral cortical areas can be used to categorize 18F-Florbetaben (FBB) PET scans by applying appropriate cutoffs. The objective of this work was first to generate FBB SUVR cutoff
Externí odkaz:
https://doaj.org/article/82f7828eacec49ea9a63d0c749624dcb
Autor:
Rong Bing, Marcus-André Deutsch, Stephanie L. Sellers, Carlos Alcaide Corral, Jack P.M. Andrews, Edwin J.R. van Beek, Sabine Bleiziffer, Wolfgang Burchert, Tim Clark, Damini Dey, Kai Friedrichs, Jan F. Gummert, Norman Koglin, Jonathon A. Leipsic, Oliver Lindner, Mark G. MacAskill, Hendrik Milting, Renzo Pessotto, Rainer Preuss, Jennifer B. Raftis, Tanja K. Rudolph, Volker Rudolph, Piotr Slomka, Andrew W. Stephens, Adriana Tavares, Evangelos Tzolos, Nick Weir, Audrey C. White, Michelle C. Williams, Reinhard Zabel, Marc R. Dweck, Verena Hugenberg, David E. Newby
Publikováno v:
Bing, R, Deutsch, M-A, Sellers, S L, Corral, C A, Andrews, J P M, van Beek, E J R, Bleiziffer, S, Burchert, W, Clark, T, Dey, D, Friedrichs, K, Gummert, J F, Koglin, N, Leipsic, J A, Lindner, O, MacAskill, M G, Milting, H, Pessotto, R, Preuss, R, Raftis, J B, Rudolph, T K, Rudolph, V, Slomka, P, Stephens, A W, Tavares, A, Tzolos, E, Weir, N, White, A C, Williams, M C, Zabel, R, Dweck, M R, Hugenberg, V & Newby, D E 2022, ' 18F-GP1 Positron Emission Tomography and Bioprosthetic Aortic Valve Thrombus ', JACC: Cardiovascular Imaging, vol. 15, no. 6, pp. 1107-1120 . https://doi.org/10.1016/j.jcmg.2021.11.015
BACKGROUND: Bioprosthetic valve thrombosis may have implications for valve function and durability.OBJECTIVES: Using a novel glycoprotein IIb/IIIa receptor radiotracer 18F-GP1, we investigated whether positron emission tomography (PET)-computed tomog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc40eec519704b34226b719aa4c53ba
https://doi.org/10.1016/j.jcmg.2021.11.015
https://doi.org/10.1016/j.jcmg.2021.11.015