Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Norman, Sachs"'
Autor:
Jennifer M. Rosenbluth, Ron C. J. Schackmann, G. Kenneth Gray, Laura M. Selfors, Carman Man-Chung Li, Mackenzie Boedicker, Hendrik J. Kuiken, Andrea Richardson, Jane Brock, Judy Garber, Deborah Dillon, Norman Sachs, Hans Clevers, Joan S. Brugge
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Organoid technology has enabled the generation of several breast cancer organoids. Here, the authors combine propagation of normal human mammary tissues with mass cytometry to evaluate the ability of organoid culture technologies to preserve stem cel
Externí odkaz:
https://doaj.org/article/9943f96aecad444bafd945d3bf8d8389
Autor:
Raphael Borie, Jonathan Cardwell, Iain R. Konigsberg, Camille M. Moore, Weiming Zhang, Sarah K. Sasse, Fabienne Gally, Evgenia Dobrinskikh, Avram Walts, Julie Powers, Janna Brancato, Mauricio Rojas, Paul J. Wolters, Kevin K. Brown, Timothy S. Blackwell, Tomoko Nakanishi, J. Brent Richards, Anthony N. Gerber, Tasha E. Fingerlin, Norman Sachs, Sara L. Pulit, Zachary Zappala, David A. Schwartz, Ivana V. Yang
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 206:1259-1270
Autor:
Geoffrey J. Lindeman, Jane E. Visvader, Daniel H.D. Gray, Gordon K. Smyth, Marco J. Herold, Stephen B. Fox, Huiling Xu, Thomas Green, Andrew Fellowes, Hans Clevers, Norman Sachs, Johanna F. Dekkers, He K. Liu, Huei-Rong Chen, Bianca D. Capaldo, Göknur Giner, Antonia N. Policheni, Elliot Surgenor, François Vaillant, James R. Whittle
Supplemental Methods and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e4dc5d909f92237b1a8f7ad74897f8
https://doi.org/10.1158/1078-0432.22475475
https://doi.org/10.1158/1078-0432.22475475
Autor:
Geoffrey J. Lindeman, Jane E. Visvader, Daniel H.D. Gray, Gordon K. Smyth, Marco J. Herold, Stephen B. Fox, Huiling Xu, Thomas Green, Andrew Fellowes, Hans Clevers, Norman Sachs, Johanna F. Dekkers, He K. Liu, Huei-Rong Chen, Bianca D. Capaldo, Göknur Giner, Antonia N. Policheni, Elliot Surgenor, François Vaillant, James R. Whittle
Purpose:Although cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors significantly extend tumor response in patients with metastatic estrogen receptor–positive (ER+) breast cancer, relapse is almost inevitable. This may, in part, reflect the failur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aef748027bdbde313a3bd818abdba09
https://doi.org/10.1158/1078-0432.c.6529083
https://doi.org/10.1158/1078-0432.c.6529083
Autor:
Geoffrey J. Lindeman, Jane E. Visvader, Daniel H.D. Gray, Gordon K. Smyth, Marco J. Herold, Stephen B. Fox, Huiling Xu, Thomas Green, Andrew Fellowes, Hans Clevers, Norman Sachs, Johanna F. Dekkers, He K. Liu, Huei-Rong Chen, Bianca D. Capaldo, Göknur Giner, Antonia N. Policheni, Elliot Surgenor, François Vaillant, James R. Whittle
Differential sgRNA enrichment from CRISPR-Cas9 genome-wide screens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094b1306d3852110a706c934b1f5d550
https://doi.org/10.1158/1078-0432.22475472
https://doi.org/10.1158/1078-0432.22475472
Autor:
Andrea L. Richardson, Norman Sachs, Deborah A. Dillon, Joan S. Brugge, Carman Man-Chung Li, Ron C. J. Schackmann, Laura M. Selfors, Mackenzie Boedicker, Hendrik J. Kuiken, Jane E. Brock, G. Kenneth Gray, Judy Garber, Hans Clevers, Jennifer M. Rosenbluth
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Recently, organoid technology has been used to generate a large repository of breast cancer organoids. Here we present an extensive evaluation of the ability of organoid culture technology to preserve complex stem/progenitor and differentiated cell t
Autor:
Jeroen Korving, Lena Böttinger, Norman Sachs, Peter J. Peters, Willine J. van de Wetering, Jelte van der Vaart, Kèvin Knoops, Kerem Eitan, Harry Begthel, Carmen López-Iglesias, Alex Gileles-Hillel, Hans Clevers, Maarten H. Geurts
Publikováno v:
EMBO Reports
Embo Reports, 22(12):e52058. Wiley
EMBO Reports, 22(12). Nature Publishing Group
Embo Reports, 22(12):e52058. Wiley
EMBO Reports, 22(12). Nature Publishing Group
Patient‐derived human organoids can be used to model a variety of diseases. Recently, we described conditions for long‐term expansion of human airway organoids (AOs) directly from healthy individuals and patients. Here, we first optimize differen
Autor:
Célia Bernard, Hans Clevers, Geanncarlo Lugo-Villarino, Céline Cougoule, Stephen Adonai Leon-Icaza, Carmen López-Iglesias, Raimond B. G. Ravelli, Christian Chalut, Serge Mazères, Kèvin Knoops, Nino Iakobachvili, Julien Mazieres, Roxane Simeone, Etienne Meunier, Christophe Guilhot, Antonio Peixoto, Norman Sachs, Peter J. Peters, Marlène Murris-Espin, Kaymeuang Cam, Olivier Neyrolles
Publikováno v:
Molecular Microbiology
Molecular Microbiology, Wiley, 2021, ⟨10.1111/mmi.14824⟩
Molecular Microbiology, 2021, ⟨10.1111/mmi.14824⟩
Molecular Microbiology, 2022, 117 (3), pp.682-692. ⟨10.1111/mmi.14824⟩
Molecular Microbiology. Wiley-Blackwell
Molecular Microbiology, 117(3), 682-692. Wiley-Blackwell
Molecular Microbiology, Wiley, 2021, ⟨10.1111/mmi.14824⟩
Molecular Microbiology, 2021, ⟨10.1111/mmi.14824⟩
Molecular Microbiology, 2022, 117 (3), pp.682-692. ⟨10.1111/mmi.14824⟩
Molecular Microbiology. Wiley-Blackwell
Molecular Microbiology, 117(3), 682-692. Wiley-Blackwell
International audience; Respiratory infections remain a major global health concern. Tuberculosis is one of the top 10 causes of death worldwide, while infections with Non-Tuberculous Mycobacteria are rising globally. Recent advances in human tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5df95e67748bc4f26b94e5d889d084
https://hal.archives-ouvertes.fr/hal-03367602
https://hal.archives-ouvertes.fr/hal-03367602
Autor:
Hans Clevers, Esmée J. van Vliet, Anne C. Rios, Jane E. Visvader, Sylvia F. Boj, Carol Piani, Heggert G Rebel, Oded Kopper, Johanna F. Dekkers, Carla S Verissimo, Jennifer M. Rosenbluth, Norman Sachs, Joan S. Brugge, Ellen J. Wehrens
Publikováno v:
Nat Protoc
Nature Protocols, 16(4), 1936-1965. Nature Publishing Group
Nature Protocols, 16(4), 1936-1965. Nature Publishing Group
Organoid technology has revolutionized the study of human organ development, disease and therapy response tailored to the individual. Although detailed protocols are available for the generation and long-term propagation of human organoids from vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40bc869d4deafc27f9ee422c5e8cc7bf
https://europepmc.org/articles/PMC8221035/
https://europepmc.org/articles/PMC8221035/
Autor:
Céline Cougoule, Serge Mazères, Hans Clevers, Norman Sachs, Peter J. Peters, Carmen López-Iglesias, Stephen Adonai Leon Icaza, Etienne Meunier, Nino Iakobachvili, Marlène Murris-Espin, Kèvin Knoops, Raimond B. G. Ravelli, Olivier Neyrolles, Roxane Simeone, Geanncarlo Lugo-Villarino, Julien Mazieres, Antonio Peixoto
Tuberculosis, one of the oldest human pathogens remains a major global health threat. Recent advances in organoid technology offer a unique opportunity to grow different human “organs” in vitro, including the human airway, that faithfully recapit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c95b5a4280f0923bf8e610fce25abc
https://doi.org/10.1101/2020.11.12.379586
https://doi.org/10.1101/2020.11.12.379586