Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Norman, Metanis"'
Autor:
Changliu Wang, Zhenguang Zhao, Reem Ghadir, Dechun Yang, Zhenjia Zhang, Zhe Ding, Yuan Cao, Yuqing Li, Rosi Fassler, Dana Reichmann, Yujie Zhang, Yongli Zhao, Can Liu, Xiaobao Bi, Norman Metanis, Junfeng Zhao
Publikováno v:
ACS Central Science, Vol 10, Iss 9, Pp 1742-1754 (2024)
Externí odkaz:
https://doaj.org/article/2710578b5d334ee38e211af88b777b07
Autor:
Mar Gil, Lareen Khouri, Imma Raurell, Diana Rafael, Fernanda Andrade, Ibane Abasolo, Simo Schwartz, María Martínez-Gómez, María Teresa Salcedo, Juan Manuel Pericàs, Diana Hide, Mingxing Wei, Norman Metanis, Joan Genescà, María Martell
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2463 (2023)
In this study, we developed functionalized polymeric micelles (FPMs) loaded with simvastatin (FPM-Sim) as a drug delivery system to target liver sinusoidal endothelial cells (LSECs) for preserving liver function in chronic liver disease (CLD). Polyme
Externí odkaz:
https://doaj.org/article/e603b3eed6d04f5284bf5147d9e90211
Autor:
Reem Mousa, Taghreed Hidmi, Sergei Pomyalov, Shifra Lansky, Lareen Khouri, Deborah E. Shalev, Gil Shoham, Norman Metanis
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-9 (2021)
Hirudin is a widely studied model for folding of disulfide-rich proteins, which folds through a slow pathway with highly heterogeneous intermediates and scrambled isomers before it reaches its native state. Here the effect of native and non-native di
Externí odkaz:
https://doaj.org/article/90ff74c53b084ca3a7d24d11009d7db6
Autor:
Orit Weil-Ktorza, Dragana Despotović, Yael Fridmann-Sirkis, Segev Naveh-Tassa, Yaacov Levy, Norman Metanis, Liam M. Longo
Homochirality of biopolymers emerged early in the history of life on Earth, nearly 4 billion years ago. Whether the establishment of homochirality was the result of abiotic physical and chemical processes, or biological selection, remains unknown. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6418b932b2ff782879c942b53ef43db9
https://doi.org/10.1101/2023.03.06.531422
https://doi.org/10.1101/2023.03.06.531422
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 469 (2021)
Protein homeostasis is an essential component of proper cellular function; however, sustaining protein health is a challenging task, especially during the aerobic lifestyle. Natural cellular oxidants may be involved in cell signaling and antibacteria
Externí odkaz:
https://doaj.org/article/62b2261475a14147bc79a27b89e54089
Autor:
Tomer Babu, Hiba Ghareeb, Uttara Basu, Hemma Schueffl, Sarah Theiner, Petra Heffeter, Gunda Koellensperger, Norman Metanis, Valentina Gandin, Ingo Ott, Claudia Schmidt, Dan Gibson
Publikováno v:
Angewandte Chemie. 135
Autor:
Hiba Ghareeb, Norman Metanis
Publikováno v:
Chemical Communications.
Salmon calcitonin (sCT) is a polypeptide hormone available in the clinic.
Autor:
Changliu Wang, Zhenguang Zhao, Reem Ghadir, Zhe Ding, Yuan Cao, Yuqing Li, Frank Qiu, Yujie Zhang, Yongli Zhao, Norman Metanis, Junfeng Zhao
Chemoselective modification of peptides and proteins has wide applications in chemical biology and pharmaceutical development. A highly efficient chemo-, regio- and stereoselective hydrosulfuration of ynamide was developed and identified as an effici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9b8e3c8a12cc437d6cc41055c9fd0ca
https://doi.org/10.21203/rs.3.rs-1982339/v1
https://doi.org/10.21203/rs.3.rs-1982339/v1
Autor:
Manas Seal, Orit Weil-Ktorza, Dragana Despotović, Dan S. Tawfik, Yaakov Levy, Norman Metanis, Liam M. Longo, Daniella Goldfarb
Publikováno v:
Journal of the American Chemical Society. 144(31)
Peptide-RNA coacervates can result in the concentration and compartmentalization of simple biopolymers. Given their primordial relevance, peptide-RNA coacervates may have also been a key site of early protein evolution. However, the extent to which s
Publikováno v:
Total Chemical Synthesis of Proteins