Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Norma N. Swanson"'
Autor:
Nigel A. Hibberts, Karin U. Schallreuter, Wayne D. Beazley, Norma N. Swanson, Mark R. Pittelkow
Publikováno v:
Journal of Investigative Dermatology. 111(3):511-516
In Hermansky–Pudlak Syndrome (HPS) a mutation in a 79.3 kDa transmembrane protein has been shown. The function of this protein has escaped definition so far. This study unveils a defective (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin (6BH 4 ) de novo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce914083bf1455c3e44c0cffcfb6b490
Autor:
Christine Ehrke, Christa Körner, Gerd Büttner, Wayne D. Beazley, Karin U. Schallreuter, Norma N. Swanson, Mark R. Pittelkow
Publikováno v:
Archives of Dermatological Research. 289:663-666
Patients with atopic eczema have significantly higher norepinephrine levels in plasma than healthy controls. In addition, significantly higher levels of the essential cofactor (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin (6BH4) were found in this patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f676f06346601188411d73fe2f354d1
https://doi.org/10.1007/s004030050258
https://doi.org/10.1007/s004030050258
Autor:
Christa Körner, Mark R. Pittelkow, Michael L. G. Gardner, Karin U. Schallreuter, Norma N. Swanson
Publikováno v:
Experimental Dermatology. 5:20-23
Human melanocytes established in MCDB-153 culture medium do not express alpha 1-, beta 1-, beta-2 adrenoceptors without extracellular stimulation. The addition of 50 x 10-9 M norepinephrine to the medium causes a time-dependent induction of alpha-1-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10277dd955a4a1893ff69c82f8a0fd8
https://doi.org/10.1111/j.1600-0625.1996.tb00088.x
https://doi.org/10.1111/j.1600-0625.1996.tb00088.x
Publikováno v:
Archives of Dermatological Research. 285:216-220
Keratinocytes were established in serum-free culture medium from lesional and nonlesional skin of a patient with vitiligo (skin type III) and from an age-matched healthy control subject. Both differentiating and undifferentiated cells were examined f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c6d99afd0a755da472d2e0f8c01258
https://doi.org/10.1007/bf00372012
https://doi.org/10.1007/bf00372012
Publikováno v:
Archives of Dermatological Research. 288:11-13
Melanocytes were successfully established from involved and uninvolved skin of a patient with acute acrofacial vitiligo. Cells from involved epidermis showed a fivefold decrease in the rate of radiolabelled 45Ca uptake compared with uninvolved and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627bbec38c2f80fc462f3f1a649f299e
https://doi.org/10.1007/bf02505036
https://doi.org/10.1007/bf02505036
Autor:
Christine Ehrke, Mark R. Pittelkow, Norma N. Swanson, John M. Wood, Karin U. Schallreuter, G. Buttner, Christa Körner
Publikováno v:
Archives of dermatological research. 288(1)
Human keratinocytes under in vitro conditions synthesize norepinephrine and epinephrine, whereas melanocytes lack this capacity. Keratinocytes established from lesional and nonlesional skin of patients with vitiligo synthesized four and two times mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0967400141197e31cfe4b2b8ca57b9c2
https://pubmed.ncbi.nlm.nih.gov/8750929
https://pubmed.ncbi.nlm.nih.gov/8750929
Autor:
Christa Körner, John M. Wood, Norma N. Swanson, Karin U. Schallreuter, G. Buttner, Mark R. Pittelkow
Publikováno v:
Biochemical and biophysical research communications. 204(1)
(6R)5,6,7,8 tetrahydrobiopterin (6-BH4) is an important cofactor in the regulation of melanogenesis in melanocytes, where it controls: (a) the supply of L-tyrosine from L-phenylalanine via phenylalanine hydroxylase, and (b) regulates directly dopaqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcd0de24536769d729767d7f0f60bca
https://pubmed.ncbi.nlm.nih.gov/7945390
https://pubmed.ncbi.nlm.nih.gov/7945390
Autor:
M Gütlich, Mark R. Pittelkow, K Hitzemann, K. R. Lemke, I Ziegler, Norma N. Swanson, W Rödl, John M. Wood, Karin U. Schallreuter
Publikováno v:
Science (New York, N.Y.). 263(5152)
The participation of (6R) 5,6,7,8-tetrahydrobiopterin (6-BH4) in regulating the tyrosine supply for melanin biosynthesis was investigated by the examination of human keratinocytes, melanocytes, and epidermal suction blisters from normal human skin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfa037c132cf247f45b8544c26ffe1f
https://pubmed.ncbi.nlm.nih.gov/8128228
https://pubmed.ncbi.nlm.nih.gov/8128228