Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Norma J. Messier"'
Autor:
Pranita K. Kabadi, April L. Rodd, Alysha E. Simmons, Norma J. Messier, Robert H. Hurt, Agnes B. Kane
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Background Multi-walled carbon nanotubes (MWCNT) have been shown to elicit the release of inflammatory and pro-fibrotic mediators, as well as histopathological changes in lungs of exposed animals. Current standards for testing MWCNTs and oth
Externí odkaz:
https://doaj.org/article/b58d8da75f9d4a029f5423d64c02d54a
Autor:
Robert H. Hurt, April L. Rodd, Alysha E. Simmons, Agnes B. Kane, Norma J. Messier, Pranita K. Kabadi
Publikováno v:
Particle and Fibre Toxicology
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-15 (2019)
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-15 (2019)
Background Multi-walled carbon nanotubes (MWCNT) have been shown to elicit the release of inflammatory and pro-fibrotic mediators, as well as histopathological changes in lungs of exposed animals. Current standards for testing MWCNTs and other nanopa
To identify the potential environmental impacts of aquatic pollutants, rapid and sensitive screening tools are needed to assess adaptive and toxic responses. This study characterizes a novel fish liver microtissue model, produced with the cell line P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc92bbcc2616a4b96dcb3145e198f396
https://europepmc.org/articles/PMC5436724/
https://europepmc.org/articles/PMC5436724/
Publikováno v:
Toxicological Sciences. 68:331-338
Asbestos fibers produce diffuse malignant mesotheliomas in chronic rodent inhalation assays or after direct intrapleural or intraperitoneal injection. In vitro models have provided evidence that asbestos fibers are genotoxic carcinogens that can dire
Publikováno v:
Toxicologic Pathology. 25:565-573
Repeated intraperitoneal injections of crocidolite asbestos fibers induced diffuse malignant mesotheliomas in mice. A series of mesothelial cell lines was isolated from mice at different stages in the development of these tumors. The cell lines isola
Publikováno v:
Hepatology. 22:1279-1288
The p53 gene is frequently mutated in human tumors; in hepatocellular carcinomas, there is a high frequency of a specific mutation at codon 249 in regions with significant aflatoxin exposure. To assess the role of this p53 mutation in the development
Autor:
Mario Perello, Isin Cakir, Omar Lansari, Charles A. Vaslet, Norma J. Messier, Eduardo A. Nillni
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 12, p e8322 (2009)
PLoS ONE, Vol 4, Iss 12, p e8322 (2009)
Sirt1 is an evolutionarily conserved NAD(+) dependent deacetylase involved in a wide range of processes including cellular differentiation, apoptosis, as well as metabolism, and aging. In this study, we investigated the role of hypothalamic Sirt1 in
Autor:
Joseph R. Testa, Charles A. Vaslet, Norma J. Messier, Agnes B. Kane, Deborah A. Altomare, I. Henderson, Kristine L Skele
Publikováno v:
Lung Cancer. 54:S5
Publikováno v:
Biochemical pharmacology. 36(22)
In contrast to their effects on mammalian cells, the nucleoside transport inhibitors nitrobenzylthioinosine 5′-monophosphate (NBMPR- P ) dilazep, benzylacyclouridine (BAU), and to a lesser extent, dipyridamole have no significant effect on the in v
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8322 (2009)
Sirt1 is an evolutionarily conserved NAD(+) dependent deacetylase involved in a wide range of processes including cellular differentiation, apoptosis, as well as metabolism, and aging. In this study, we investigated the role of hypothalamic Sirt1 in
Externí odkaz:
https://doaj.org/article/739d8c280fbc438dbe25461e7bbbb7c6