Výsledky vyhledávání - "Norma J Nowak"

Akademický článek

Genomic profiling and spatial SEIR modeling of COVID-19 transmission in Western New York

Autor: Jonathan E. Bard, Na Jiang, Jamaal Emerson, Madeleine Bartz, Natalie A. Lamb, Brandon J. Marzullo, Alyssa Pohlman, Amanda Boccolucci, Norma J. Nowak, Donald A. Yergeau, Andrew T. Crooks, Jennifer A. Surtees

Publikováno v: Frontiers in Microbiology, Vol 15 (2024)

The COVID-19 pandemic has prompted an unprecedented global effort to understand and mitigate the spread of the SARS-CoV-2 virus. In this study, we present a comprehensive analysis of COVID-19 in Western New York (WNY), integrating individual patient-

Externí odkaz: https://doaj.org/article/fa9888eb670147d8b97771961280f8fd

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Akademický článek

Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation.

Autor: Song Yao, Lara E Sucheston, Shannon L Smiley, Warren Davis, Jeffrey M Conroy, Norma J Nowak, Christine B Ambrosone, Philip L McCarthy, Theresa Hahn

Publikováno v: PLoS ONE, Vol 6, Iss 10, p e25940 (2011)

Bone mineral density (BMD) loss commonly occurs after hematopoietic cell transplantation (HCT). Hypothesizing that genetic variants may influence post-HCT BMD loss, we conducted a prospective study to examine the associations of single nucleotide pol

Externí odkaz: https://doaj.org/article/6eb332c3a6c643a8ba8812c753207ab9

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Akademický článek

Upregulation of hemoglobin expression by oxidative stress in hepatocytes and its implication in nonalcoholic steatohepatitis.

Autor: Wensheng Liu, Susan S Baker, Robert D Baker, Norma J Nowak, Lixin Zhu

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24363 (2011)

Recent studies revealed that hemoglobin is expressed in some non-erythrocytes and it suppresses oxidative stress when overexpressed. Oxidative stress plays a critical role in the pathogenesis of non-alcoholic steatohepatitis (NASH). This study was de

Externí odkaz: https://doaj.org/article/bfe6f333704f4db2b4ef077a21ced0a1

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Akademický článek

Role of alcohol metabolism in non-alcoholic steatohepatitis.

Autor: Susan S Baker, Robert D Baker, Wensheng Liu, Norma J Nowak, Lixin Zhu

Publikováno v: PLoS ONE, Vol 5, Iss 3, p e9570 (2010)

BackgroundNon-alcoholic steatohepatitis (NASH) is a serious form of non-alcoholic fatty liver disease (NAFLD), associated with obesity and insulin resistance. Previous studies suggested that intestinal bacteria produced more alcohol in obese mice tha

Externí odkaz: https://doaj.org/article/c68229f3aa424b2a8e35179268046f0e

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Akademický článek

Targeted deletion of p73 in mice reveals its role in T cell development and lymphomagenesis.

Autor: Alice Nemajerova, Gustavo Palacios, Norma J Nowak, Sei-Ichi Matsui, Oleksi Petrenko

Publikováno v: PLoS ONE, Vol 4, Iss 11, p e7784 (2009)

Transcriptional silencing of the p73 gene through methylation has been demonstrated in human leukemias and lymphomas. However, the role of p73 in the malignant process remains to be explored. We show here that p73 acts as a T cell-specific tumor supp

Externí odkaz: https://doaj.org/article/a130b5005cae4e8fb18a4765ffd7bda4

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Akademický článek

Multimodal Dimension Reduction and Subtype Classification of Head and Neck Squamous Cell Tumors

Autor: Jonathan E. Bard, Norma J. Nowak, Michael J. Buck, Satrajit Sinha

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Traditional analysis of genomic data from bulk sequencing experiments seek to group and compare sample cohorts into biologically meaningful groups. To accomplish this task, large scale databases of patient-derived samples, like that of TCGA, have bee

Externí odkaz: https://doaj.org/article/54ec01c5aed740febbaf53f57adb5380

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