Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Norma A. Maloney"'
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 26(5)
With the markedly reduced usage of aluminum salts in renal failure, parathyroid hormone (PTH) has become the major determinant of currently seen bone disease. Clinicians now must consider what PTH level should be sought. Too low a level may lead to t
Autor:
Gino V. Segre, Stanley S. A. Fenton, Celia M. T. Greenwood, York Pei, Arif Manuel, Norma A. Maloney, Carl Saiphoo, Gavril Hercz, Donald J. Sherrard
Publikováno v:
Kidney international. 43(2)
The spectrum of bone disease in end-stage renal failure—An evolving disorder. We have assessed the bone histology in 259 chronic dialysis patients, all of whom were in the same dialysis program. All patients had bone biopsies with quantitative hist
Autor:
Allen C. Alfrey, Norma A. Maloney, Donald J. Sherrard, Nancy L. Miller, Jack W. Coburn, Anthony B. Hodsman, Susan M. Ott, Arnold S. Brickman
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 54:539-546
To evaluate the relationship between aluminum and the characteristics of bone disease in uremia, bone aluminum content and quantitative histomorphometric analysis of bone were evaluated in bone biopsies from 59 uremic patients undergoing maintenance
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 39:119-135
Twenty-two patients with chronic uremia were separated into 3 groups on the basis of quantitative bone histology: 1) mild (10 patients); 2) osteomalacic (6); and 3) fibrotic (6). In the mild group there was an increase in forming surface; in the oste
Publikováno v:
The Journal of clinical endocrinology and metabolism. 65(1)
The bone histology in patients with chronic renal failure and aluminum-related bone disease does not always show the excess accumulation of unmineralized osteoid (matrix) characteristic of osteomalacia. Frequently, bone aluminum accumulation is assoc
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 1(5)
Twenty-seven asymptomatic patients treated with hemodialysis longer than 8 years (mean 12.9 ± 3.1 years) underwent bone biopsy to determine the prevalence of aluminum-associated bone disease. None had excess aluminum exposure from the dialysate. Ten
Publikováno v:
The New England journal of medicine. 307(12)
A histochemical stain for bone aluminum allowed us to determine the prevalence and staining characteristics of aluminum in renal osteodystrophy. The staining method correlated well with the results of atomic-absorption studies in 96 samples (r = 0.81
Autor:
Jack W. Coburn, David B. Endres, Norma A. Maloney, Jeffrey B. Kopp, Dennis L. Andress, Donald J. Sherrard
Publikováno v:
The Journal of clinical endocrinology and metabolism. 63(5)
Bone biopsies were studied in 67 dialysis patients to determine if a PTH RIA specific for intact plasma PTH is a better predictor of osteitis fibrosa than a RIA that measures inactive carboxy-terminal/midregion plasma PTH fragments. An amino-terminal
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 12(3)
Serial bone biopsies obtained from 19 chronic hemodialysis patients asymptomatic for bone disease were examined retrospectively. We found only modest amounts of stainable bone aluminum after the first few years of hemodialysis therapy. Over the ensui
Publikováno v:
The New England journal of medicine. 312(8)
In some patients with chronic renal failure, bone mineralization becomes defective after parathyroidectomy for secondary hyperparathyroidism. Because aluminum deposition in bone is associated with impaired bone formation and osteomalacia, we retrospe