Výsledky vyhledávání - "Norm Alliare"

FRI0216B SELECTIVE IRAK4 INHIBITOR DAMPENS MYD88 SIGNALING AND AMELIORATES INFLAMMATION AND FIBROSIS IN A MOUSE MODEL OF LUPUS NEPHRITIS

Autor: Dania Rabah, Ti Wang, Jeffery Vessels, Kevin Guckian, Chris Roberts, Andrea Bertolotti-Ciarlet, Norm Alliare, Agnes Gardet, Holly M. Legault, Ramon G. Bonegio, Ian R. Rifkin

Publikováno v: Poster Presentations.

Background IRAK4 is an important signaling mediator of the innate immune system. IRAK4 initiates MyD88-dependent signaling from most TLRs and from IL-1Rs, resulting in downstream production of pro-inflammatory cytokines1. Objectives Inhibition of IRA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfbca7ad35dae288f2965000b98162f2
https://doi.org/10.1136/annrheumdis-2019-eular.3385

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