Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Noriyuki Murai"'
Publikováno v:
The Japanese Journal of Phlebology. 34:29-33
Autor:
Kana Shimizu, Yoichi Sunagawa, Masafumi Funamoto, Hiroki Honda, Yasufumi Katanasaka, Noriyuki Murai, Yuto Kawase, Yuta Hirako, Takahiro Katagiri, Harumi Yabe, Satoshi Shimizu, Nurmila Sari, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1268 (2021)
Drug repositioning has recently emerged as a strategy for developing new treatments at low cost. In this study, we used a library of approved drugs to screen for compounds that suppress cardiomyocyte hypertrophy. We identified the antiplatelet drug s
Externí odkaz:
https://doaj.org/article/7aeb417de74a4b29a84df531f85bb03d
Autor:
Yoshihiro Matsumoto, Takahiro Masaki, Yoshihiro Mezaki, Akira Yoshikawa, Noriyuki Murai, Mamoru Aizawa, Ayasa Tajima, Tomokazu Matsuura, Mariko Nakamura, Hideki Aizaki, Soichi Kojima, Takahiko J. Fujimi
Publikováno v:
Human Cell
Cell lines are powerful tools for research into liver function at the molecular level. However, they are generally unsuitable for rigorously assessing the effects of amino acid composition, because many lines require serum-containing medium for their
Autor:
Kana Shimizu, Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Satoshi Shimizu, Noriyuki Murai, Koji Hasegawa, Tatsuya Morimoto
Publikováno v:
Circulation. 144
Introduction: Recently, the cost of new drug development is increasing year by year, and drug repositioning is being used as a strategy for developing new treatments by saving time and costs. We used a library of approved drugs to screen for compound
Autor:
Masafumi Funamoto, Tatsuya Morimoto, Kana Shimizu, Satoshi Shimizu, Noriyuki Murai, Koji Hasegawa, Yasufumi Katanasaka, Yoichi Sunagawa, Yusuke Miyazaki
Publikováno v:
Circulation Research. 129
Purpose: The cost of new drug development is increasing year by year, and drug repositioning is being used as a strategy to develop new treatments at low-cost. We used a library of approved drugs to screen for compounds that suppress cardiomyocyte hy
Autor:
Noriyuki Murai, Kazutoshi Yoshitake, Takahisa Furukawa, Senya Matsufuji, Zenichi Matsui, Hiroyuki Satoh, Tsuyoshi Takamura, Hiroyuki Kubo, Takashi Yokoo, Takeshi Iwata, Yoshihiro Omori, Satoshi Katagiri, Takaaki Hayashi, Tadashi Nakano
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Senior Løken syndrome (SLS) is a heterogeneous disorder characterized by severe retinal degenerations and juvenile-onset nephronophthisis. Genetic variants in ten different genes have been reported as the causes of SLS. Clinical evaluation of a pati
Autor:
Koichi Kawamoto, Noriko Goto, Senya Matsufuji, Masamitsu Konno, Kazuhiko Hayashi, Keisuke Tamari, Yuichiro Doki, Kazuhiko Ogawa, Hideshi Ishii, Shinji Tanaka, Masaki Mori, Fumiaki Isohashi, Jun Koseki, Taroh Satoh, Noriyuki Murai, Ayumu Asai
Publikováno v:
Cell Death Discovery, Vol 4, Iss 1, Pp 1-9 (2018)
Cell Death Discovery
Cell Death Discovery
Cancer stem cells (CSCs) exhibit tumorigenic potential and can generate resistance to chemotherapy and radiotherapy. A labeled ornithine decarboxylase (ODC, a rate-limiting enzyme involved in polyamine [PA] biosynthesis) degradation motif (degron) sy
Autor:
Noriyuki Murai
Most of the proteins in eukaryotic cells are degraded by the proteasome in an ubiquitin-dependent manner. However, ubiquitin-independent protein degradation pathway by the 26S proteasome exists in the cells. Ornithine decarboxylase (ODC) is a well-kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e2eea9670183a9bec2d38141558d58
https://doi.org/10.5772/intechopen.92623
https://doi.org/10.5772/intechopen.92623
Autor:
Yoichi Sunagawa, Kana Shimizu, Tatsuya Morimoto, Masafumi Funamoto, Hiroki Honda, Nurmila Sari, Yusuke Miyazaki, Yoshiki Kawakami, Koji Hasegawa, Satoshi Shimizu, Noriyuki Murai, Yasufumi Katanasaka, Hiromichi Wada
Publikováno v:
Circulation. 142
Introduction: Serotonin (5-HT), a neurohormone involved in a wide range of physiological functions, has generated much interest in recent years regarding its potential role in cardiac function. It is reported that sarpogrelate, a selective 5-HT2A rec
Autor:
Makoto Mihara, Hisako Hara, Yohei Hayashi, Mitsunaga Narushima, Takumi Yamamoto, Takeshi Todokoro, Takuya Iida, Naoya Sawamoto, Jun Araki, Kazuki Kikuchi, Noriyuki Murai, Taro Okitsu, Iori Kisu, Isao Koshima
Publikováno v:
PLoS ONE, Vol 8, Iss 5 (2013)
Externí odkaz:
https://doaj.org/article/95ed17e1234e494eae1c9d99311541fd