Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Noriyuki Izutani"'
Autor:
Takenori Ishizawa, Koichi Takahashi, Kentaro Asanuma, Shigeo Sato, Kenji Nohmi, Ryohchi Suzuki, Tadashi Morikawa, Tomoyuki Watanabe, Yoshinobu Higuchi, Akie Homma, Tatsuya Tamura, Makoto Kanda, Noriyuki Izutani, Takashi Emura, Kazuaki Maeda, Hironoshin Kitagawa, Haruhiko Sato, Tadao Yamazaki, Masahisa Ikemi, Hitoshi Ikeya, Tetsu Matsuura, Tatsuya Kato, Akira Okamachi, Hidetomo Kitamura
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:1062-1075
We previously reported that a conjugate of hyaluronic acid (HA) and methotrexate (MTX) could be a prototype for future osteoarthritis drugs having the efficacy of the two clinically validated agents but with a reduced risk of the systemic side effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9e38bdd739bd26edc8ffc09e1081fb
https://doi.org/10.1016/j.bmc.2009.12.053
https://doi.org/10.1016/j.bmc.2009.12.053
Autor:
Noriyuki Izutani, Keisuke Nagahisa, Akinori Nakato, Takashi Gojobori, Tomokazu Shirai, Suteaki Shioya, Eiichiro Kimura, Akihiko Yamagishi, Yutaka Kawarabayasi, Hiroshi Shimizu
Publikováno v:
Metabolic Engineering. 7:59-69
In amino acid production by coryneform bacteria, study on relationship between change in enzyme activities and production of a target amino acid is important. In glutamate production, Kawahara et al. discovered that the effect of decrease in 2-oxoglu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7f047c9fbf95c63ed1d32ffa277aa0
https://doi.org/10.1016/j.ymben.2004.10.001
https://doi.org/10.1016/j.ymben.2004.10.001
Autor:
Hironoshin Kitagawa, Tadao Yamazaki, Makoto Kanda, Tomoyuki Watanabe, Tatsuya Tamura, Takenori Ishizawa, Haruhiko Sato, Tatsuya Kato, Noriyuki Izutani, Koichi Takahashi, Ryochi Suzuki, Masahisa Ikemi, Kentaro Asanuma, Shigeo Sato, Akira Okamachi, Yoshinobu Higuchi, Akie Homma, Hidetomo Kitamura, Kazuaki Maeda, Tadashi Morikawa, Hitoshi Ikeya, Tetsu Matsuura, Kenji Nohmi, Takashi Emura
Publikováno v:
Bioorganicmedicinal chemistry. 17(13)
Hyaluronic acid (HA) provides synovial fluid viscoelasticity and has a lubricating effect. Injections of HA preparations into the knee joint are widely used as osteoarthritis therapy. The current HA products reduce pain but do not fully control infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2554a522282b6398500465adad50ca47
https://pubmed.ncbi.nlm.nih.gov/19457673
https://pubmed.ncbi.nlm.nih.gov/19457673