Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Noriyuki, Sugo"'
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103432- (2024)
Summary: Single-molecule imaging (SMI) is a powerful approach to quantify the spatiotemporal dynamics of transcription in living cells. Here, we describe a protocol of SMI for transcription and epigenetic factors in human cortical neurons derived fro
Externí odkaz:
https://doaj.org/article/4fef402219bf485785a462cc6d2fded3
Autor:
Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, Mikio Hoshino, Akito Nakao, Yasuo Mori, Shigeo Okabe, Masayuki Matsushita, Anja Urbach, Yuta Katayama, Akinobu Matsumoto, Keiichi I Nakayama, Shota Katori, Takuya Sato, Takuji Iwasato, Haruko Nakamura, Yoshio Goshima, Matthieu Raveau, Tetsuya Tatsukawa, Kazuhiro Yamakawa, Noriko Takahashi, Haruo Kasai, Johji Inazawa, Ikuo Nobuhisa, Tetsushi Kagawa, Tetsuya Taga, Mohamed Darwish, Hirofumi Nishizono, Keizo Takao, Kiran Sapkota, Kazutoshi Nakazawa, Tsuyoshi Takagi, Haruki Fujisawa, Yoshihisa Sugimura, Kyosuke Yamanishi, Lakshmi Rajagopal, Nanette Deneen Hannah, Herbert Y Meltzer, Tohru Yamamoto, Shuji Wakatsuki, Toshiyuki Araki, Katsuhiko Tabuchi, Tadahiro Numakawa, Hiroshi Kunugi, Freesia L Huang, Atsuko Hayata-Takano, Hitoshi Hashimoto, Kota Tamada, Toru Takumi, Takaoki Kasahara, Tadafumi Kato, Isabella A Graef, Gerald R Crabtree, Nozomi Asaoka, Hikari Hatakama, Shuji Kaneko, Takao Kohno, Mitsuharu Hattori, Yoshio Hoshiba, Ryuhei Miyake, Kisho Obi-Nagata, Akiko Hayashi-Takagi, Léa J Becker, Ipek Yalcin, Yoko Hagino, Hiroko Kotajima-Murakami, Yuki Moriya, Kazutaka Ikeda, Hyopil Kim, Bong-Kiun Kaang, Hikari Otabi, Yuta Yoshida, Atsushi Toyoda, Noboru H Komiyama, Seth GN Grant, Michiru Ida-Eto, Masaaki Narita, Ken-ichi Matsumoto, Emiko Okuda-Ashitaka, Iori Ohmori, Tadayuki Shimada, Kanato Yamagata, Hiroshi Ageta, Kunihiro Tsuchida, Kaoru Inokuchi, Takayuki Sassa, Akio Kihara, Motoaki Fukasawa, Nobuteru Usuda, Tayo Katano, Teruyuki Tanaka, Yoshihiro Yoshihara, Michihiro Igarashi, Takashi Hayashi, Kaori Ishikawa, Satoshi Yamamoto, Naoya Nishimura, Kazuto Nakada, Shinji Hirotsune, Kiyoshi Egawa, Kazuma Higashisaka, Yasuo Tsutsumi, Shoko Nishihara, Noriyuki Sugo, Takeshi Yagi, Naoto Ueno, Tomomi Yamamoto, Yoshihiro Kubo, Rie Ohashi, Nobuyuki Shiina, Kimiko Shimizu, Sayaka Higo-Yamamoto, Katsutaka Oishi, Hisashi Mori, Tamio Furuse, Masaru Tamura, Hisashi Shirakawa, Daiki X Sato, Yukiko U Inoue, Takayoshi Inoue, Yuriko Komine, Tetsuo Yamamori, Kenji Sakimura, Tsuyoshi Miyakawa
Publikováno v:
eLife, Vol 12 (2024)
Increased levels of lactate, an end-product of glycolysis, have been proposed as a potential surrogate marker for metabolic changes during neuronal excitation. These changes in lactate levels can result in decreased brain pH, which has been implicate
Externí odkaz:
https://doaj.org/article/15de117935204a21a8487997042e8094
Publikováno v:
BMC Neuroscience, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background CRISPR/Cas9 system is a powerful method to investigate the role of genes by introducing a mutation selectively and efficiently to specific genome positions in cell and animal lines. However, in primary neuron cultures, this method
Externí odkaz:
https://doaj.org/article/a29879fbf344471ebd39d7822a9d2a0b
Autor:
Ricardo Alchini, Haruka Sato, Naoyuki Matsumoto, Tomomi Shimogori, Noriyuki Sugo, Nobuhiko Yamamoto
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract During development, thalamocortical (TC) axons form branches in an activity-dependent fashion. Here we investigated how neuronal activity is converted to molecular signals, focusing on an epigenetic mechanism involving histone deacetylases (
Externí odkaz:
https://doaj.org/article/395131c25061436dbca24b8a988bdd92
Autor:
Nobuhiko Yamamoto, Takeshi Yagi, Kohei Onishi, Tsuyoshi Miyakawa, Noriyuki Sugo, Akiko Uyeda, Teruyoshi Hirayama, Satoko Hattori
Publikováno v:
J Neurosci
Genome stability is essential for brain development and function, asde novomutations during neuronal development cause psychiatric disorders. However, the contribution of DNA repair to genome stability in neurons remains elusive. Here, we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807d961f5f4f7f72e9f3e0d1f1cdd836
https://europepmc.org/articles/PMC7672999/
https://europepmc.org/articles/PMC7672999/
Publikováno v:
Neuromethods ISBN: 9781071605318
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2880943aa40cc767d56de8e230b4b2c3
https://doi.org/10.1007/978-1-0716-0532-5_4
https://doi.org/10.1007/978-1-0716-0532-5_4
Publikováno v:
BMC Neuroscience, Vol 18, Iss 1, Pp 1-9 (2017)
BMC Neuroscience
BMC Neuroscience
Background CRISPR/Cas9 system is a powerful method to investigate the role of genes by introducing a mutation selectively and efficiently to specific genome positions in cell and animal lines. However, in primary neuron cultures, this method is affec
Autor:
Tomomi Shimogori, Haruka Sato, Ricardo Alchini, Noriyuki Sugo, Nobuhiko Yamamoto, Naoyuki Matsumoto
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
During development, thalamocortical (TC) axons form branches in an activity-dependent fashion. Here we investigated how neuronal activity is converted to molecular signals, focusing on an epigenetic mechanism involving histone deacetylases (HDACs). I
Autor:
Nobuhiko Yamamoto, Takeshi Yagi, Satoko Hattori, Noriyuki Sugo, Akiko Uyeda, Kohei Onishi, Tsuyoshi Miyakawa, Teruyoshi Hirayama
Genome stability is essential for brain development and function. However, the contribution of DNA repair to genome stability in neurons remains elusive. Here, we demonstrate that the base excision repair protein Polβ is involved in hippocampal neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb66042190c8c4d9506c498cd65a714
Autor:
Noriyuki Sugo, Yoshiyuki Arai, Toshio Yanagida, Nobuhiko Yamamoto, Hironobu Kitagawa, Masatoshi Morimatsu
Publikováno v:
The Journal of Neuroscience. 37:1-10
Transcriptional regulation is crucial for neuronal activity-dependent processes that govern neuronal circuit formation and synaptic plasticity. An intriguing question is how neuronal activity influences the spatiotemporal interactions between transcr