Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Noriyasu, Imai"'
2
Improved performance of the SH test as an in vitro skin sensitization test with a new predictive model and decision tree
Autor: Noriyasu, Imai, Midori, Takeyoshi, Sakiko, Aizawa, Mika, Tsurumaki, Masaharu, Kurosawa, Akemi, Toyoda, Maki, Sugiyama, Kaoru, Kasahara, Shinichi, Ogata, Takashi, Omori, Morihiko, Hirota
Publikováno v: Journal of Applied Toxicology. 42:1029-1043
Demands for the elimination and replacement of animal experiments for cosmetic safety assessment have increased in recent years. Evaluation of skin sensitization, however, is a critical issue in cosmetic safety assessment. The SH test is an in vitro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8cbe7e39d6ff4262575b584cc9de74
https://doi.org/10.1002/jat.4275
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3
A Step-by-Step Approach for Assessing Human Skin Irritation Without Animal Testing for Quasi-Drugs and Cosmetic Products
Autor: Hiroaki Todo, Hitoshi Sakaguchi, Masahiko Yamaguchi, Akiko Yagami, Morihiko Hirota, Hidefumi Ikeda, Masato Hatao, Keiko Yamamoto, Tokio Nakada, Mariko Sugiyama, Hajime Kojima, Mio Yagi, Yoshiaki Ikarashi, Noriyasu Imai, Jihei Nishimura
Publikováno v: Applied In Vitro Toxicology. 7:144-154
Introduction: Animal tests of cosmetic ingredients and products have been banned in the EU since 2013. However, in Japan, the application of new quasi-drugs requires the generation of 24-hour data ...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b9cb28c71592e27a1e151419ebc51f7
https://doi.org/10.1089/aivt.2021.0016
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4
Enhancing between-facility reproducibility of the SH test as an in vitro skin sensitization test by the improved test method
Autor: Maki Sugiyama, Morihiko Hirota, Midori Takeyoshi, Noriyasu Imai, Sakiko Aizawa, Masaharu Kurosawa, Kaoru Kasahara, Mika Tsurumaki, Akemi Toyoda, Shinichi Ogata
Publikováno v: The Journal of Toxicological Sciences. 46:235-248
There has been an increased demand to eliminate animal experiments and to replace the experiments with alternative tests for assessing the safety of cosmetics. The SH test is an in vitro skin sensitization test that evaluates the protein binding abil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73d7a133fb67d5cd15f3998a37ef136c
https://doi.org/10.2131/jts.46.235
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5
Transferability and within- and between-laboratory reproducibilities of EpiSensA for predicting skin sensitization potential in vitro: A ring study in three laboratories
Autor: Kazutoshi Saito, Megumi Sakuma, Mayu Ikezumi, Mika Watanabe, Hiroko Motohashi, Midori Takeyoshi, Masaaki Miyazawa, Noriyasu Imai, Hideyuki Mizumachi, Asami Umetsu, Hiroko Okutomi
Publikováno v: Journal of Applied Toxicology. 38:1233-1243
The epidermal sensitization assay (EpiSensA) is an in vitro skin sensitization test method based on gene expression of four markers related to the induction of skin sensitization; the assay uses commercially available reconstructed human epidermis. E
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28fcac7196d38f009fcd72e614656243
https://doi.org/10.1002/jat.3634
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8
Transferability and within- and between-laboratory reproducibilities of EpiSensA for predicting skin sensitization potential in vitro: A ring study in three laboratories
Autor: Hideyuki, Mizumachi, Megumi, Sakuma, Mayu, Ikezumi, Kazutoshi, Saito, Midori, Takeyoshi, Noriyasu, Imai, Hiroko, Okutomi, Asami, Umetsu, Hiroko, Motohashi, Mika, Watanabe, Masaaki, Miyazawa
Publikováno v: Journal of applied toxicology : JAT. 38(9)
The epidermal sensitization assay (EpiSensA) is an in vitro skin sensitization test method based on gene expression of four markers related to the induction of skin sensitization; the assay uses commercially available reconstructed human epidermis. E
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0720eb9820d3bfd972a76375c4a7c228
https://pubmed.ncbi.nlm.nih.gov/29722446
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9
Evaluation of combinations ofin vitrosensitization test descriptors for the artificial neural network-based risk assessment model of skin sensitization
Autor: Kenji Okamoto, Shinichi Watanabe, Shiho Fukui, Daisuke Sekiya, Takao Ashikaga, Toshihiko Kasahara, Noriyasu Imai, Masaharu Fujita, Masaaki Miyazawa, Hirokazu Seto, Miyuki Fujishiro, Yoshinao Kato, Akemi Toyoda, Osamu Takenouchi, Satoru Kurotani, Morihiko Hirota, Daiki Kyotani
Publikováno v: Journal of Applied Toxicology. 35:1333-1347
The skin sensitization potential of chemicals has been determined with the use of the murine local lymph node assay (LLNA). However, in recent years public concern about animal welfare has led to a requirement for non-animal risk assessment systems f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::122313fff58e0085be10647eab411743
https://doi.org/10.1002/jat.3105
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