Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Norioki Ohno"'
Publikováno v:
Clinical and Experimental Immunology. 190:268-279
Summary Regulatory T cells (Tregs) control immune responses by suppressing various inflammatory cells. Tregs in newborn babies may play an important role in preventing excessive immune responses during their environmental change. We examined the numb
Autor:
Yasuhiko Sera, Syuhei Karakawa, Teruyuki Kajiume, Masao Kobayashi, Nobutsune Ishikawa, Norioki Ohno
Publikováno v:
Stem Cell Discovery. :25-30
The Polycomb group protein Bmi1 is a constituent of the Polycomb repressive complex 1, and it is an important molecule for the regulation of the self-renewal of hematopoietic stem cells. In the field of clinical hematology, there are reports that the
Autor:
Yoshihiro Takihara, Tomoki Kawai, Norioki Ohno, Ryuta Nishikomori, Satoshi Okada, Masao Kobayashi, Motoaki Ohtsubo, Miyuki Tsumura, Yoko Mizoguchi, Shin'ichiro Yasunaga, Takemasa Sakaguchi, Shuhei Karakawa
Publikováno v:
Journal of Clinical Immunology. 31:762-772
X-linked ectodermal dysplasia with immunodeficiency (XL-ED-ID) is caused by hypomorphic mutations in NEMO, which encodes nuclear factor-kappaB (NF-κB) essential modulator. We identified a novel mutation, 769-1 G>C, at the splicing acceptor site of e
Autor:
Teruyuki Kajiume, Keiichi Hara, Norioki Ohno, Tomoaki Yoshida, Masao Kobayashi, Hiroshi Kawaguchi
Publikováno v:
Pediatric Hematology and Oncology. 26:375-380
Kasabach-Merritt syndrome is a life-threatening congenital disorder characterized by an enlarging hemangioma, thrombocytopenia, and consumption coagulopathy. We report the case of a one-month male infant who presented with a large cutaneous tumor in
Publikováno v:
Stem cells and development. 18(8)
Human umbilical cord blood (CB) has been used successfully in stem cell transplantation. A subpopulation of CD34(+) cells expresses chemokine receptor CXCR4 which is critical for bone marrow engraftment in human hematopoietic stem cells. Here, we dem
Publikováno v:
Experimental hematology. 37(7)
Objective The Polycomb -group ( PcG ) genes regulate global gene expression in many biological processes, including hematopoiesis, by manipulating specific target genes. It is known that various PcG genes regulate self-renewal of hematopoietic stem c
Publikováno v:
Platelets. 23:399-400
EDTA-dependent pseudothrombocytopenia (PTCP) is characterised by a low platelet count caused by autoantibodies in the serum reacting with EDTA-anticoagulated blood. EDTA-dependent PTCP is caused by a factor that retains EDTA anticoagulation activity
Publikováno v:
Blood. 120:4724-4724
Abstract 4724 Erythropoietin (EPO), which is used to treat anemic immature neonates, is thought to be effective for treating neonatal hypoxic encephalopathy by stimulating nervous system cells or vascular stem cells. On stem cells, CXCR4 is an import
Autor:
Ryuta Nishikomori, Tomoki Kawai, Motoaki Ohtsubo, Norioki Ohno, Masao Kobayashi, Shin'ichiro Yasunaga, Shuhei Karakawa, Yoshihiro Takihara, Miyuki Tsumura, Satoshi Okada, Yoko Mizoguchi
Publikováno v:
Blood. 116:1732-1732
Abstract 1732 X-linked ectodermal dysplasia with immunodeficiency (XL-EDA-ID) is caused by hypomorphic mutations in the nuclear factor κB (NF-κB) essential modulator (NEMO) gene, also called IKBKG, and these mutations impair but do not abolish NF-
Publikováno v:
Blood. 112:1721-1721
Human umbilical cord blood (CB) is rich source of hematopoietic stem cells (HSCs) and provides an attractive alternative to bone marrow or mobilized peripheral blood transplantation. However, major disadvantage of CB transplantation is the relatively