Imaging of Metastatic Cancer Cells in Sentinel Lymph Nodes using Affibody Probes and Possibility of a Theranostic Approach

Autor: Makoto Tsuchimochi, Haruka Yamaguchi, Kazuhide Hayama, Yasuo Okada, Tomoyuki Kawase, Takamasa Suzuki, Norio Tsubokawa, Noriaki Wada, Atsushi Ochiai, Satoshi Fujii, Hirofumi Fujii

Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 2, p 427 (2019)

The accurate detection of lymph node metastases is essential for treatment success in early-stage malignant cancer. Sentinel lymph node (SLN) biopsy is the most effective procedure for detecting small or micrometastases that are undetectable by conve

Externí odkaz: https://doaj.org/article/eceb532e1b454b039148318a8647e01b

Dual-Labeled Near-Infrared/99mTc Imaging Probes Using PAMAM-Coated Silica Nanoparticles for the Imaging of HER2-Expressing Cancer Cells

Autor: Haruka Yamaguchi, Makoto Tsuchimochi, Kazuhide Hayama, Tomoyuki Kawase, Norio Tsubokawa

Publikováno v: International Journal of Molecular Sciences, Vol 17, Iss 7, p 1086 (2016)

We sought to develop dual-modality imaging probes using functionalized silica nanoparticles to target human epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer cells and achieve efficient target imaging of HER2-expressing tumors. P

Externí odkaz: https://doaj.org/article/33611e2bc29540c8b782e8c422dc7579

Fabrication of a poly(dimethylsiloxane) microstructured surface imprinted from patterned silicon wafer with a self-cleaning property

Autor: Tetsuo Sakka, Takeshi Yamauchi, Tetsu Mitsumata, Eri Takahashi, Shunsuke Kosugi, Shingo Tamesue, Kazuhiro Fukami, Norio Tsubokawa

Publikováno v: Polymer Journal. 48:835-838

Microrod patterns were fabricated on PDMS sheets utilizing porous silicon wafers as templates. The prepared microrod PDMS surface showed high water and oil contact angles. To discuss the mechanism, theoretical contact angles were calculated utilizing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39d0594338dfb1231a6b84b03210cc60
https://doi.org/10.1038/pj.2016.34

Synthesis of Monodisperse Hydrophobic Silicone Particles in the Submicron Size

Autor: Takeshi Yamauchi, Mitsuharu Matsuzawa, Shingo Tamesue, Kenji Takai, Norio Tsubokawa

Publikováno v: Journal of the Japan Society of Colour Material. 89:107-112

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::436ff743a57d5aff54731672113b91b8
https://doi.org/10.4011/shikizai.89.107

HER2-Targeted Multifunctional Silica Nanoparticles Specifically Enhance the Radiosensitivity of HER2-Overexpressing Breast Cancer Cells

Autor: Norio Tsubokawa, Makoto Tsuchimochi, Haruka Yamaguchi, Kazuhide Hayama, Ichiro Sasagawa, Yasuo Okada, Tomoyuki Kawase

Publikováno v: International Journal of Molecular Sciences; Volume 19; Issue 3; Pages: 908
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 3, p 908 (2018)

We investigated the effects of targeted functionalized silica nanoparticles on the radiosensitivity of cancer cells. Better control of the local concentration of silica nanoparticles may facilitate their use as an adjuvant in conjunction with ionizin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd41287181cc1b571c01eb186a9e5162