Výsledky vyhledávání - "Norio Kurihara"

Enantioselective recognition of mono-demethylated methoxychlor metabolites by the estrogen receptor

Autor: Miki Akamatsu, Hisashi Miyagawa, Shizuka Nakagami, Masahiro Miyashita, Takahiro Shimada, Norio Kurihara

Publikováno v: Chemosphere. 54:1273-1276

Metabolites of methoxychlor such as 2-(p-hydroxyphenyl)-2-(p-methoxyphenyl)-1,1,1-trichloroethane (mono-OH-MXC) and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane (bis-OH-MXC), have estrogenic activity. Mono-OH-MXC is a chiral compound in which the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf77e61b41e03bb9891e2cb98a6bc58f
https://doi.org/10.1016/j.chemosphere.2003.10.035

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Application of Deuterium Isotope Effects to the Xenobiotic Metabolism Study

Autor: Norio Kurihara

Publikováno v: Journal of the Mass Spectrometry Society of Japan. 46:157-172

Deuterium substitution of certain hydrogen atoms in a molecule may change its metabolism rate in various biological systems. Some of the deuterium labeled pesticides were metabolized in some in vitro systems, such as rat liver microsomes and purified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dec2a7cc54212ea898be99d99dac2911
https://doi.org/10.5702/massspec.46.157

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Effects of Cytochrome P450 Antibodies on the Oxidative Demethylation of Methoxychlor Catalyzed by Rat Liver Microsomal Cytochrome P450 Isozymes: Isozyme Specificity and Alteration of Enantiotopic Selectivity

Autor: Daisuke Kishimoto, Norio Kurihara

Publikováno v: Pesticide Biochemistry and Physiology. 56:44-52

Anti-CYP2B1 added to the methoxychlor reaction medium catalyzed by phenobarbital-treated rat liver microsomes altered the enantiotopic selectivity of the reaction, in favor of the (S)-mono-O-demethylated metabolite. In the reaction with untreated liv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10d2216395de67e21188322a9c8f342f
https://doi.org/10.1006/pest.1996.0057

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Structural Effects ofN-Arylcarbamoylpyrazolines on Calcium Uptake in Rat Brain Synaptosomes

Autor: Norio Kurihara, Keiichiro Nishimura, Tamio Ueno, Riaz Hasan, Yoshiaki Nakagawa

Publikováno v: Pesticide Science. 46:221-225

N-Arylcarbamoylpyrazolines with various substituents at the para position of the carbamoyl benzene ring inhibited ATP-dependent Ca 2+ -uptake in synaptosomes prepared from the rat brain. The activity of these compounds was evaluated as log(1/I 50 ),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6fb36d09eb93ae8fd47d45d5688a9c83
https://doi.org/10.1002/(sici)1096-9063(199603)46:3<221::aid-ps348>3.0.co

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Rate Parameter Changes by Added Albumin in the Microsomal Oxidative Demethylation of Deuteriated and Non-deuteriated 4-Methoxyanisole

Autor: Norio Kurihara, Masatoshi Masuda, Daisuke Kishimoto

Publikováno v: Bioscience, Biotechnology, and Biochemistry. 60:806-810

Bovine serum albumin (BSA) added to the reaction medium for the oxidative demethylation of 4-methoxyanisole and its "di-CD3" isotopomer ([d6]methoxyanisole), when catalyzed by liver microsomes from untreated rats, decreased the Km values and increase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a60879584adb8382decc69c257226f6
https://doi.org/10.1271/bbb.60.806

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Quantitative structure-activity studies of insect growth regulators. XI. Stimulation and inhibition ofN-acetylglucosamine incorporation in a cultured integument system by substitutedN-tert-butyl-N,N′-dibenzoylhydrazines

Autor: Keiichiro Nishimura, Tamio Ueno, Yoshihiro Soya, Nobuhiro Oikawa, Katsumi Nakai, Toshio Fujita, Yoshiaki Nakagawa, Norio Kurihara

Publikováno v: Pesticide Science. 43:339-345

The ability to stimulate N-acetylglucosamine (GluNAc) incorporation in-vitro of a number of N-tert-butyl-N,N′-dibenzoylhydrazines having various substituents on both phenyl rings was measured in cultured integument excised from the rice stem borer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e509894da92984251ec07f1ad38969d9
https://doi.org/10.1002/ps.2780430414

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