Výsledky vyhledávání - "Norio Fukuhara"

Stability of Novel Siderophore Cephalosporin S-649266 against Clinically Relevant Carbapenemases

Autor: Tsukasa Ito-Horiyama, Keizo Yamaguchi, Yoshikazu Ishii, Yoshinori Yamano, Masakatsu Tsuji, Norio Fukuhara, Kazuhiro Tateda, Takafumi Sato, Akinobu Ito, Rio Nakamura

Publikováno v: Antimicrobial agents and chemotherapy. 60(7)

To better understand the antibacterial activity of S-649266 against carbapenemase producers, its stability against clinically relevant carbapenemases was investigated. The catalytic efficiencies ( k cat / K m ) of IMP-1, VIM-2, and L1 for S-649266 we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089cbb48397f9b3ab920cc23c9e1ca8c
https://pubmed.ncbi.nlm.nih.gov/27139465

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Control of Bacteria Adhesion by Cell-Wall Engineering

Autor: Kenichi Niikura, Reiko Sadamoto, Shin-Ichiro Nishimura, Taichi Ueda, Kenji Monde, Norio Fukuhara

Publikováno v: Journal of the American Chemical Society. 126:3755-3761

UDP-MurNAc-pentapeptide derivative bacterial cell-wall precursors were synthesized as effective tools for surface display on living bacteria. Lactobacilli were incubated in the ketone-modified precursor-containing medium, and the ketone moiety was di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1ea778142e3c2700201513faf5699e
https://doi.org/10.1021/ja039391i

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Isolation and mutation site determination of the temperature-sensitivemurBmutants ofStaphylococcus aureus

Autor: Kazuhisa Sekimizu, Kenji Kurokawa, Kenji Miura, Hideki Maki, Yan Li, Chikara Kaito, Haruto Takimura, Miki Matsuo, Norio Fukuhara, Satoshi Nishida, Kazuhisa Murakami

Publikováno v: FEMS Microbiology Letters. 222:107-113

The murB gene encodes UDP-N-acetylenolpyruvylglucosamine reductase and functions in bacterial peptidoglycan biosynthesis. A plasmid carrying the murB gene restored the temperature-sensitive growth of six Staphylococcus aureus mutants, in which peptid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29bc9eaf953760d9714aee9605d2493
https://doi.org/10.1016/s0378-1097(03)00260-x

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TAL1 and LIM-Only Proteins Synergistically Induce Retinaldehyde Dehydrogenase 2 Expression in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3

Autor: Norio Fukuhara, Osamu Yoshie, Yuichi Ono

Publikováno v: Molecular and Cellular Biology. 18:6939-6950

Previously, we have shown that TAL1 and the LIM-only protein gene (LMO) are regularly coactivated in T-cell acute lymphoblastic leukemia (T-ALL). This observation is likely to relate to the findings that TAL1 and LMO are highly synergistic in T-cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e244181ecaef5308403929813ec43c9
https://doi.org/10.1128/mcb.18.12.6939

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Transcriptional Activity of TAL1 in T Cell Acute Lymphoblastic Leukemia (T-ALL) Requires RBTN1 or −2 and Induces TALLA1, a Highly Specific Tumor Marker of T-ALL

Autor: Osamu Yoshie, Norio Fukuhara, Yuichi Ono

Publikováno v: Journal of Biological Chemistry. 272:4576-4581

TAL1, which is frequently activated in T cell acute lymphoblastic leukemia (T-ALL), encodes lineage-specific basic helix-loop-helix (bHLH) proteins that bind specifically to E-box DNA motif upon dimerization with ubiquitous basic helix-loop-helix pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd82b5944f832b11d36eaafe900d452
https://doi.org/10.1074/jbc.272.7.4576

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Synthesis and in vitro/in vivo antibacterial activity of oxazolidinones having thiocarbamate at C-5 on the A-ring and an amide- or urea-substituted [1,2,5]triazepane or [1,2,5]oxadiazepane as the C-ring

Autor: Tatsuro Yasukata, Hideyuki Suzuki, Tsutomu Iwaki, Koichi Shudo, Iwao Utsunomiya, Norio Fukuhara

Publikováno v: European journal of medicinal chemistry. 69

Oxazolidinones bearing a seven-membered [1,2,5]triazepane or [1,2,5]oxadiazepane heterocycle substituted with an amide or urea functionality as the C-ring and having a [1,2,3]triazole, a thiocarbamate, an isoxazole-3-ylamino, or a thioacetamide C-5 s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dea15ee61b402b7ea291057a5b99bd
https://pubmed.ncbi.nlm.nih.gov/24044938

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Identification of a highly specific surface marker of T-cell acute lymphoblastic leukemia and neuroblastoma as a new member of the transmembrane 4 superfamily

Autor: Shin Takagi, Shigeru Tsuchiya, Norio Fukuhara, Toshio Imai, Tasuke Konno, Masayoshi Minegishi, Kiyomi Fujikawa, Yorio Hinuma, Osamu Yoshie, Kenji Fukudome

Publikováno v: International Journal of Cancer. 61:706-715

Five monoclonal antibodies detected a surface antigen expressed exclusively on T-cell acute lymphoblastic leukemia (T-ALL) in a panel of 45 human hematopoietic cell lines, including T-cell lines derived from adult T-cell leukemia and those establishe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a56b77cea26ff29b79ce2fa151b6e1e
https://doi.org/10.1002/ijc.2910610519

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Strong induction of ICAM-1 in human T cells transformed by human T-cell-leukemia virus type 1 and depression of ICAM-1 or LFA-1 in adult T-cell-leukemia-derived cell lines

Autor: Satoshi Orita, Yorio Hinuma, Norio Fukuhara, Shin Takagi, Morio Nagira, Mikio Furuse, Toshio Imai, Osamu Yoshie, Kenji Fukudome

Publikováno v: International Journal of Cancer. 52:418-427

Sixteen human T-cell lines were studied for the expression of a cell-adhesion molecule ICAM-1 and its counter-receptor LFA-1. The cell lines included 3 human T-cell-leukemia-virus-type-I (HTLV-1)-negative cell lines derived from acute lymphoblastic l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32fc65ee953cd187741a6f885390b9b
https://doi.org/10.1002/ijc.2910520316

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