Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Norio Doi"'
Autor:
Angkana Chaiprasert, Chanwit Tribuddharat, Areeya Disratthakit, Manoon Leechawengwongs, Iyarit Thaipisuttikul, Therdsak Prammananan, Norio Doi
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:5189-5197
DNA gyrase mutations are a major cause of quinolone resistance in Mycobacterium tuberculosis . We therefore conducted the first comprehensive study to determine the diversity of gyrase mutations in pre-extensively drug-resistant (pre-XDR) ( n = 71) a
Autor:
Masayuki Igarashi, Seiko Hattori, Yoshiaki Takahashi, Norio Doi, Yuzuru Akamatsu, Naoko Nakagawa, Yoshiko Koyama, Toshiaki Miyake, Kanae Ishikawa, Kunio Inoue, Yasuhiro Komatsuki, Hiromi Soutome
Publikováno v:
The Journal of Antibiotics. 66:171-178
Acidic treatment of a mixture of caprazamycins (CPZs) A-G isolated from a screen of novel antimycobacterial agents gave caprazene, a core structure of CPZs, in high yield. Chemical modification of the resulting caprazene was performed to give its var
Autor:
Takeshi Taketani, Nobuhiro Nishimura, Kohji Naora, Takeshi Kasai, Seiji Yamaguchi, Rie Kanai, George Hayashi, Tomochika Uemura, Norio Doi, Kikuo Iwamoto
Publikováno v:
YAKUGAKU ZASSHI. 129:759-766
A traditional Chinese herbal medicine, Kampo medicine, maoto, has been widely used in the treatment of febrile symptoms caused by viral infection. This herbal extract granule for oral use, however, is not well accepted by infants or young children du
Autor:
Norio Doi, Angkana Chaiprasert, Shinji Meada, Areeya Disratthakit, Iyarit Thaipisuttikul, Therdsak Prammananan
Publikováno v:
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 32
Drug-resistant tuberculosis (TB), which includes multidrug-resistant (MDR-TB), quinolone-resistant (QR-TB) and extensively drug-resistant tuberculosis (XDR-TB), is a serious threat to TB control. We aimed to characterize the genotypic diversity of dr
Publikováno v:
The Journal of Antibiotics. 56:580-583
Autor:
Norio Doi, Yasuhiro Horita
Predicting drug-drug interactions (DDIs) related to cytochrome P450 (CYP), such as CYP3A4 and one of the major drug transporters, P-glycoprotein (P-gp), is crucial in the development of future chemotherapeutic regimens to treat tuberculosis (TB) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848fc6a60c7944e07260c05e7dfcd03f
https://europepmc.org/articles/PMC4068461/
https://europepmc.org/articles/PMC4068461/
Autor:
Yoshinobu Fukatsu, Takuya Matsunaga, Noriko Shimokawa, Tomokazu Shimada, Tatsuya Fujisawa, Takuya Iyoda, Muneaki Takada, Norio Doi, Fumio Fukai, Shunsuke Kumokoshi, Kimiko Makino, Hiroshi Terada
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(9)
Following inhalation of Mycobacterium tuberculosis, including bacillus Calmette–Guérin (BCG), pathogens enter and grow inside macrophages by taking advantage of their phagocytic mechanisms. Macrophages often fail to eliminate intracellular M. tube
Autor:
Areeya Disratthakit, Norio Doi
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:2684-2686
The in vitro activities of DC-159a against seven species of Mycobacterium were compared with moxifloxacin, gatifloxacin, levofloxacin, and rifampin. DC-159a was the most active compound against quinolone-resistant multidrug-resistant M. tuberculosis
Publikováno v:
BIOCHEMISTRY. 47(47):12257-12259
To enhance DNA cleavage by zinc-finger nucleases (ZFNs), we sandwiched a DNA cleavage enzyme with two artificial zinc-finger proteins (AZPs). Because the DNA between the two AZP-binding sites is cleaved, the AZP-sandwiched nuclease is expected to bin
Publikováno v:
Antimicrobial agents and chemotherapy. 55(8)
A G88C mutation in GyrA is one of the key alterations by which Mycobacterium tuberculosis mutants acquire DC-159a resistance in vitro . A novel double mutation in GyrA, G88C D94H, conferred high DC-159a resistance. Different mutation patterns in GyrA