Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Norio Asai"'
Autor:
Takao Ishigami, Koji Ueshima, Masashi Ukai, Norio Asai, Hajime Takamatsu, Masanori Yokono, Masahiro Takeda, Noriyuki Masuda
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 4, Pp 333-339 (2019)
The pharmacological profile of ASP2205 fumarate (ASP2205), a novel 5-HT2C receptor agonist, was evaluated in vitro and in vivo. ASP2205 showed potent and selective agonistic activity for the human 5-HT2C receptor, with an EC50 of 0.85 nM in the intra
Externí odkaz:
https://doaj.org/article/f7385d2365d44bb1b66c078429fae33f
Autor:
Hironori Mori, Norio Asai
Publikováno v:
IEEJ Transactions on Power and Energy. 143:396-401
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b25844d873bf8fea4c0995ca905d17c
https://doi.org/10.1541/ieejpes.143.396
https://doi.org/10.1541/ieejpes.143.396
Autor:
Toshihiro Watanabe, Koichi Yonezawa, Takahiro Kuramochi, Kazuhiro Ikegai, Seiji Tamura, Norio Asai, Tetsuo Kiso, Akio Kamikawa, Satoshi Miyamoto, Takemoto Yukihiro, Hiromasa Oka, Shohei Shirakami
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:3716-3726
A new series of transient receptor potential vanilloid type 1 (TRPV1) antagonists were designed and synthesized from N-(3-hydroxyphenyl)-2-(piperidin-1-ylmethyl)biphenyl-4-carboxamide hydrochloride (8). SAR studies identified (R)-N-(1-methyl-2-oxo-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e645480def4cc351f241cf20a0e41756
https://doi.org/10.1016/j.bmc.2018.06.001
https://doi.org/10.1016/j.bmc.2018.06.001
Autor:
Satoshi Ohno, M. Tsunoda, Yoshio Kusakabe, Masashi Nakamura, Takashi Yokogawa, Toshiya Senda, Kazuo T. Nakamura, Tomohisa Moriguchi, Norio Asai, Mitsuo Sekine, Nobutada Tanaka, Kazuya Nishikawa
Publikováno v:
Nucleic Acids Research
The specific aminoacylation of tRNA by tyrosyl-tRNA synthetases (TyrRSs) relies on the identity determinants in the cognate tRNA(Tyr)s. We have determined the crystal structure of Saccharomyces cerevisiae TyrRS (SceTyrRS) complexed with a Tyr-AMP ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc27c31074ee2ebd020409eefad35ef
https://doi.org/10.1093/nar/gkm417
https://doi.org/10.1093/nar/gkm417
Autor:
Varaporn Vuddhakul, Mitsuaki Nishibuchi, Tsutomu Koitabashi, Yoshitsugu Nakaguchi, Norio Asai, Tadaaki Morigaki, Son Radu
Publikováno v:
Microbiology and Immunology. 50:135-148
Nine Escherichia coli O157: H7/- strains isolated primarily from non-clinical sources in Thailand and Japan carried the stx(2) gene but did not produce Stx2 toxin in a reversed passive latex agglutination (RPLA) assay. A strain (EDL933) bearing a stx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e424556d95647cb4dfcc68df10bcac
https://doi.org/10.1111/j.1348-0421.2006.tb03779.x
https://doi.org/10.1111/j.1348-0421.2006.tb03779.x
Publikováno v:
The Journal of Organic Chemistry. 67:3290-3300
This paper describes the first synthesis of phosmidosine and phosmidosine B, i.e., nucleotide antibiotics composed of 8-oxoadenosine and L-proline which are connected via a unique N-acyl phosphoramidate linkage. Phosmidosine has a yet-undetermined ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7005defe863110f39341c771c9d412a8
https://doi.org/10.1021/jo016176g
https://doi.org/10.1021/jo016176g
Autor:
Yuki Tokoi, Shannon D. Manning, Hiroshi Nakajima, Yuka Kojima, Atsushi Iguchi, Takashi Hatakeyama, Yuhki Nagai, Nanami Asoshima, Mitsuhiro Kameyama, Hiromi Nakamura, Hiroyuki Ueno, Kikuyo Ogata, Tomoko Morita-Ishihara, Shinya Kawanishi, Yuji Migita, Seiya Harada, Yoshiki Etoh, Hideki Kobayashi, Keiko Nishi, Kaori Iwabuchi, Yukiko Hara-Kudo, Tsutomu Kubota, Ichiro Furukawa, Takayuki Kurazono, Kiyoshi Tominaga, Takashi Hirochi, Jun Terajima, Kanda Takashi, Hidemasa Izumiya, Hideki Naitoh, Tomomi Kono, Yumiko Sakamoto, Yuko Matsumoto, Norio Asai, Yukiko Asano, Makoto Ohnishi, Toshiro Kuroki, Koji Kikuchi, Sachiko Ichihara, Kazuko Seto, Hitomi Kasahara, Keiko Tanaka, Keiko Kimata, Jun Yatsuyanagi, Kunihiko Nakane, Reiko Arai, Junko Isobe, Noriko Konishi, Kimiko Kawano, Tomoko Kitahashi, Mikiko Honda, Madoka Hamada, Sunao Iyoda, Mitsuteru Takamura, Masakado Matsumoto, Takehito Saitoh, Yutaka Shiraki, Kazuki Chiba, Yoshitoshi Ogura, Hiroaki Satoh, Junko Yabata, Hiromi Obata, Masao Kawase, Kazutoshi Matsumoto, Junichi Tanabe, Midori Hiroi, Jun Kudaka, Etsuko Saitoh, Kazumi Horikawa, Akemi Kai
Publikováno v:
Open Forum Infectious Diseases
EHEC O157:H7 clade 6 strains harboring stx2a and/or stx2c and clade 8 strains harboring stx2a or stx2a/stx2c were frequently associated with childhood HUS cases in Japan. Rapid and specific detection of such lineages are required for infection contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262e71588ec33b182761a4364b7d4033
https://pubmed.ncbi.nlm.nih.gov/25734131
https://pubmed.ncbi.nlm.nih.gov/25734131
Publikováno v:
Tetrahedron Letters. 41:5881-5885
A new antitumor active phosmidosine A, which was isolated from Streptomyces sp., was successfully synthesized by a series of reactions involving construction of the N -acyl phosphoramidate linkage which was achieved by the reaction of the 5′- O -ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79b253399d1904af6bd9859f5b0fcc2e
https://doi.org/10.1016/s0040-4039(00)00926-6
https://doi.org/10.1016/s0040-4039(00)00926-6
Autor:
Tadaaki Morigaki, Norio Asai, Punnee Pungrasamee, Nuanjira Patararungrong, Siroj Jitsurong, Varaporn Vuddhakul, Mitsuaki Nishibuchi
Publikováno v:
FEMS Microbiology Letters. 182:343-347
Antibody to Escherichia coli O157 lipopolysaccharide was detected in the sera of healthy individuals more frequently in Southern Thailand than in Japan. The result suggested possible exposure of Thai people to E. coli O157. E. coli O157:H7 or O157:H(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768ceae2341e3394782fbdfb62cc92aa
https://doi.org/10.1111/j.1574-6968.2000.tb08919.x
https://doi.org/10.1111/j.1574-6968.2000.tb08919.x
Autor:
Haruo Watanabe, Mitsuaki Nishibuchi, Norio Asai, Chiho Matsumoto, Tadaaki Morigaki, Yung Bu Kim, Jun Okuda
Publikováno v:
FEMS Microbiology Letters. 166:43-48
Escherichia coli strains isolated from patients with diarrhea or hemolytic uremic syndrome (HUS) at Pusan University Hospital, South Korea, between 1990 and 1996 were examined for traits of the O157:H7 serogroup. One strain isolated from a patient wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824dd72e2c493cbac9d5ed09c873bac5
https://doi.org/10.1111/j.1574-6968.1998.tb13181.x
https://doi.org/10.1111/j.1574-6968.1998.tb13181.x