Výsledky vyhledávání - "Norio Sawabu"

Multiple factors influencing the release of hTERT mRNA from pancreatic cancer cell lines inin vitroculture

Autor: Yoshiharu Motoo, Gensaku Okada, Koushiro Ohtsubo, Hisatsugu Mouri, Hiroyuki Watanabe, Norio Sawabu, Yasushi Yamaguchi

Publikováno v: Cell Biology International. 36:545-553

Since telomerase expression is highly prevalent in human cancers, the quantitation of serum/plasma hTERT (human telomerase reverse transcriptase) mRNA levels may be useful for early detection of PCa (pancreatic cancer). To analyse the correspondence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edac163d262eaab0ce990cb735a8b575
https://doi.org/10.1042/cbi20090471

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Advanced hepatocellular carcinoma treated effectively with irinotecan via hepatic arterial infusion followed by proton beam therapy

Autor: Yasushi Yamaguchi, Hisatsugu Mouri, Junichiro Sanada, Koushiro Ohtsubo, Osamu Matsui, Takashi Okai, Tokuji Kitamura, Koichi Tokuuye, Hiroyuki Watanabe, Norio Sawabu, Tomoya Tsuchiyama, Yoshiharu Motoo, Ryusuke Fujiki

Publikováno v: Journal of Infection and Chemotherapy. 15(5):316-321

金沢大学医学部附属病院がん高度先進治療センター
We report a 48-year-old man with hepatocellular carcinoma (HCC) treated with hepatic arterial infusion (HAI) chemotherapy followed by proton beam therapy. The HCC lesion in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d0033b706aea105b7336a08bf36c1d
http://hdl.handle.net/2297/19911

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Appropriate steroid therapy for autoimmune pancreatitis based on long-term outcome

Autor: Atsutake Okamoto, Hiroyuki Watanabe, Norio Sawabu, Tokio Wakabayashi, Terumi Kamisawa

Publikováno v: Scandinavian Journal of Gastroenterology. 43:609-613

Because autoimmune pancreatitis (AIP) responds well to corticosteroids, many AIP patients are given this treatment. However, there is no consensus on the indications, dose, or duration of steroid treatment. The aim of this study was to establish the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0fde1f69bcb2225e0a0f864af022d2
https://doi.org/10.1080/00365520701731263

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Preproenkephalin hypermethylation in the pure pancreatic juice compared with p53 mutation in the diagnosis of pancreatic carcinoma

Autor: Hisatsugu Mouri, Koushiro Ohtsubo, F. Yao, Yasushi Yamaguchi, Hiroyuki Watanabe, Norio Sawabu, Gensaku Okada

Publikováno v: Journal of Gastroenterology. 41:791-797

Aberrant methylation of CpG islands is a common mechanism for the dysregulation of tumor suppressor genes in a variety of human malignancies. Preproenkephalin ppENK) hypermethylation is recognized in 90% of pancreatic carcinoma (PCa) tissues, but not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7138cd594821bd0753e95f4b69d765b6
https://doi.org/10.1007/s00535-006-1857-3

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Effect of gemcitabine on the expression of apoptosis-related genes in human pancreatic cancer cells

Autor: Norio Sawabu, Toshinari Minamoto, Pei-Hong Jiang, Yoshiharu Motoo

Publikováno v: World Journal of Gastroenterology. 12(10):1597-1602

金沢大学がん研究所
Aim: To investigate the expression of genes involved in the gemcitabine-induced cytotoxicity in human pancreatic cancer cells. Methods: A human pancreatic cancer cell line, PANC-1, was cultured. 1 × 104 PANC-1 cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce45af39d90fee76f01f4d97e1759f8
http://hdl.handle.net/2297/11866

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Expression of Mesothelin mRNA in Pure Pancreatic Juice From Patients With Pancreatic Carcinoma, Intraductal Papillary Mucinous Neoplasm of the Pancreas, and Chronic Pancreatitis

Autor: Norio Sawabu, Tokio Wakabayashi, Yasushi Yamaguchi, Gensaku Okada, Hiroyuki Watanabe, Yoshiharu Motoo, Hisatsugu Mouri, Koushiro Ohtsubo

Publikováno v: Pancreas. 30:349-354

In the gene expression analysis of pancreatic carcinoma (PCa) using serial analysis of gene expression (SAGE) according to Ryu et al, the tag for the mesothelin mRNA transcript was present in 7 of 8 SAGE libraries derived from PCa but not in the 2 SA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d949a986bb39b4467c739d89a469e4ba
https://doi.org/10.1097/01.mpa.0000160281.56828.76

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A Pilot Study of Individualized Maximum Repeatable Dose (iMRD), a New Dose Finding System, of Weekly Gemcitabine for Patients With Metastatic Pancreas Cancer

Autor: Kenji Nishioka, Yutaka Takahashi, Masayoshi Mai, Norio Sawabu

Publikováno v: Pancreas. 30:206-210

We developed and established a new dose-finding system, the individualized maximum repeatable dose (iMRD), suitable to induce prolonged TTP rather than tumor shrinkage.We applied this system in weekly gemcitabine therapy for 18 metastatic pancreas ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2336c0c953c128377c31f8797a7d40ac
https://doi.org/10.1097/01.mpa.0000153335.73352.c7

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Epidermoid cyst of the intrapancreatic accessory spleen producing CA19-9

Autor: Kaname Yamashita, Hisatsugu Mouri, Toshinari Minamoto, Toshifumi Gabata, Yoshiharu Motoo, Hiroyuki Watanabe, Norio Sawabu, Koushiro Ohtsubo, Yasushi Yamaguchi

Publikováno v: Digestive Endoscopy. 16:244-248

We report a rare case of an epidermoid cyst in an accessory spleen at the pancreatic tail with producing CA19-9. A 55-year-old female was admitted to our hospital, Cancer Research Institute, Kanazawa University, for close examination of a cystic lesi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ccf410248e3f43458e534e255abef4c
https://doi.org/10.1111/j.1443-1661.2004.00347.x

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Abnormalities of tumor suppressor gene p16 in pancreatic carcinoma: immunohistochemical and genetic findings compared with clinicopathological parameters

Autor: Hiroyuki Watanabe, Takashi Okai, Yasushi Yamaguchi, Yoshiharu Motoo, Norio Sawabu, Yu-Xin Hu, Koushiro Ohtsubo

Publikováno v: Journal of Gastroenterology. 38:663-671

Background. Abnormalities of the tumor suppressor gene p16 have been reported in a variety of human tumors but are rare in pancreatic carcinoma except for cancer cell lines and xenografts. Their clinicopathological significance remains unknown. The p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb79507acdc4deed250b01f9d2e1a713
https://doi.org/10.1007/s00535-003-1119-6

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Visualizing the gastric wall with a 30-MHz ultrasonic miniprobe: ex vivo imaging of normal gastric sites and sites of early gastric cancer

Autor: Toshinari Minamoto, Masayoshi Mai, Takashi Okai, Norio Sawabu, Eman A. Sabet

Publikováno v: Abdominal Imaging. 28:252-256

Background: This study was performed to determine the echo layer structures of the normal gastric wall and early gastric cancer when visualized with a 30-MHz ultrasonic miniprobe. Methods: Twelve surgically resected gastric specimens were used for an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02b85fd2b152e44c9eb6bcc7c20841b
https://doi.org/10.1007/s00261-002-0035-1

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