Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Norimitsu Ban"'
Autor:
Deokho Lee, Yohei Tomita, Yukihiro Miwa, Heonuk Jeong, Ari Shinojima, Norimitsu Ban, Shintaro Yamaguchi, Ken Nishioka, Kazuno Negishi, Jun Yoshino, Toshihide Kurihara
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14711 (2022)
Cardiovascular abnormality-mediated retinal ischemia causes severe visual impairment. Retinal ischemia is involved in enormous pathological processes including oxidative stress, reactive gliosis, and retinal functional deficits. Thus, maintaining ret
Externí odkaz:
https://doaj.org/article/e6d6f342d7a84fd8a995d561e9aeab4f
Autor:
Deokho Lee, Yohei Tomita, Yukihiro Miwa, Ari Shinojima, Norimitsu Ban, Shintaro Yamaguchi, Ken Nishioka, Kazuno Negishi, Jun Yoshino, Toshihide Kurihara
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11228 (2022)
Retinal ischemia/reperfusion (I/R) injury can cause severe vision impairment. Retinal I/R injury is associated with pathological increases in reactive oxygen species and inflammation, resulting in retinal neuronal cell death. To date, effective thera
Externí odkaz:
https://doaj.org/article/25e13aa056fc4b9eb4d70761ec2d4b56
Autor:
Yo Sasaki, Hiroki Kakita, Shunsuke Kubota, Abdoulaye Sene, Tae Jun Lee, Norimitsu Ban, Zhenyu Dong, Joseph B Lin, Sanford L Boye, Aaron DiAntonio, Shannon E Boye, Rajendra S Apte, Jeffrey Milbrandt
Publikováno v:
eLife, Vol 9 (2020)
Leber congenital amaurosis type nine is an autosomal recessive retinopathy caused by mutations of the NAD+ synthesis enzyme NMNAT1. Despite the ubiquitous expression of NMNAT1, patients do not manifest pathologies other than retinal degeneration. Her
Externí odkaz:
https://doaj.org/article/4275e0ca179049eabb78a4c6222a8885
Autor:
Maho Sato, Sakiko Minami, Norihiro Nagai, Misa Suzuki, Toshihide Kurihara, Ari Shinojima, Hideki Sonobe, Kunihiko Akino, Norimitsu Ban, Kazuhiro Watanabe, Atsuro Uchida, Hajime Shinoda, Kazuo Tsubota, Yoko Ozawa
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240357 (2020)
The clinical course of age-related macular degeneration (AMD) is related to choroidal conditions, and can be determined by the evaluation of the central choroidal thickness (CCT). The aim of this study was to determine the association between the axi
Externí odkaz:
https://doaj.org/article/28254cebf331432e8db7871973a16d15
Autor:
Norimitsu Ban, Tae Jun Lee, Abdoulaye Sene, Zhenyu Dong, Andrea Santeford, Jonathan B. Lin, Daniel S. Ory, Rajendra S. Apte
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 8, Pp 1414-1423 (2018)
Photoreceptors have high intrinsic metabolic demand and are exquisitely sensitive to metabolic perturbation. In addition, they shed a large portion of their outer segment lipid membranes in a circadian manner, increasing the metabolic burden on the o
Externí odkaz:
https://doaj.org/article/f37d5b70129147069a9c4ae9a8dbc85e
Autor:
Jonathan B. Lin, Abdoulaye Sene, Andrea Santeford, Hideji Fujiwara, Rohini Sidhu, Marianne M. Ligon, Vikram A. Shankar, Norimitsu Ban, Indira U. Mysorekar, Daniel S. Ory, Rajendra S. Apte
Publikováno v:
EBioMedicine, Vol 32, Iss , Pp 9-20 (2018)
Macrophage aging is pathogenic in numerous diseases, including age-related macular degeneration (AMD), a leading cause of blindness in older adults. Although prior studies have explored the functional consequences of macrophage aging, less is known a
Externí odkaz:
https://doaj.org/article/affa62f8204a49bdbf413e70b5b10010
Autor:
Norimitsu Ban, Yoko Ozawa, Hideto Osada, Jonathan B. Lin, Eriko Toda, Mitsuhiro Watanabe, Kenya Yuki, Shunsuke Kubota, Rajendra S. Apte, Kazuo Tsubota
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 3, Iss 1, Pp 1-10 (2017)
Author Summary Sirtuins are nicotinamide adenine dinucleotide-dependent protein deacetylases. Among seven sirtuins, SIRT3 is a key regulator of mitochondrial function. However, functions of SIRT3 in the retina are largely unknown. In this study, we i
Externí odkaz:
https://doaj.org/article/92495cab1dba4cccbc679a25927d2256
Autor:
Naymel Alejandra Guzmán Mendoza, Kohei Homma, Hideto Osada, Eriko Toda, Norimitsu Ban, Norihiro Nagai, Kazuno Negishi, Kazuo Tsubota, Yoko Ozawa
Publikováno v:
Antioxidants, Vol 10, Iss 7, p 1147 (2021)
Exposure to excessive visible light causes retinal degeneration and may influence the progression of retinal blinding diseases. However, there are currently no applied treatments. Here, we focused on endoplasmic reticulum (ER) stress, which can cause
Externí odkaz:
https://doaj.org/article/a239b234a13b4d6fbcffdf0363932dd8
Autor:
Jonathan J. Miner, Abdoulaye Sene, Justin M. Richner, Amber M. Smith, Andrea Santeford, Norimitsu Ban, James Weger-Lucarelli, Francesca Manzella, Claudia Rückert, Jennifer Govero, Kevin K. Noguchi, Gregory D. Ebel, Michael S. Diamond, Rajendra S. Apte
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3208-3218 (2016)
Zika virus (ZIKV) is an emerging flavivirus that causes congenital abnormalities and Guillain-Barré syndrome. ZIKV infection also results in severe eye disease characterized by optic neuritis, chorioretinal atrophy, and blindness in newborns and con
Externí odkaz:
https://doaj.org/article/766a998ca629426fbdb33df443eb65d9
Autor:
Jonathan B. Lin, Shunsuke Kubota, Norimitsu Ban, Mitsukuni Yoshida, Andrea Santeford, Abdoulaye Sene, Rei Nakamura, Nicole Zapata, Miyuki Kubota, Kazuo Tsubota, Jun Yoshino, Shin-ichiro Imai, Rajendra S. Apte
Publikováno v:
Cell Reports, Vol 17, Iss 1, Pp 69-85 (2016)
Photoreceptor death is the endpoint of many blinding diseases. Identifying unifying pathogenic mechanisms in these diseases may offer global approaches for facilitating photoreceptor survival. We found that rod or cone photoreceptor-specific deletion
Externí odkaz:
https://doaj.org/article/ad5b3619cf5149aa8ea7fff5633aedfd