Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Noriko Yamano-Adachi"'
Autor:
Meutia Diva Hakim, Noriko Yamano- Adachi, Takeshi Omasa, Marselina Irasonia Tan, Lia Dewi Juliawaty, Ernawati Arifin Giri-Rachman
Publikováno v:
Journal of Mathematical and Fundamental Sciences, Vol 54, Iss 3 (2023)
Hepatitis B immunoglobulin (HBIG) is an effective treatment for hepatitis B, including postexposure prophylaxis of HBV infection, prevention of HBV reinfection in liver transplant patients, and reducing sexual transmission. This study investigated th
Externí odkaz:
https://doaj.org/article/e93c52fa9cc94824a06a76e0ba7e5ad1
Autor:
Hakim, Meutia Diva1,2, Noriko Yamano-Adachi2, Takeshi Omasa2, Juliawaty, Lia Dewi3, Giri-Rachman, Ernawati Arifin4, Tan, Marselina Irasonia1 marsel@itb.ac.id
Publikováno v:
Journal of Mathematical & Fundamental Sciences. 2023, Vol. 54 Issue 3, p290-301. 12p.
Autor:
Noriko Yamano‐Adachi, Yuto Nakanishi, Wataru Tanaka, YuanShan Lai, Masahiro Yamazaki, Laura Zenner, Hirofumi Hata, Takeshi Omasa
Publikováno v:
Biotechnology and Bioengineering. 120:659-673
Chinese hamster ovary (CHO) cells are major host cells for biopharmaceuticals. During culture, the chromosome number of CHO cells alters spontaneously. Here, we investigated the effects of artificial changes in the chromosome number on productivity.
Autor:
Ryo Misaki, Masashi Iwasaki, Hiroki Takechi, Noriko Yamano-Adachi, Takao Ohashi, Hiroyuki Kajiura, Kazuhito Fujiyama
Publikováno v:
Cytotechnology
Although antibodies have attracted attention as next-generation biopharmaceuticals, the costs of purifying the products and of arranging the environment for cell cultivation are high. Therefore, there is a need to increase antibody efficacy and impro
Publikováno v:
Traffic. 22:425-438
GRP94 (glucose-regulated protein 94) is a well-studied chaperone with a lysine, aspartic acid, glutamic acid and leucine (KDEL) motif at its C-terminal, which is responsible for GRP94 localization in the endoplasmic reticulum (ER). GRP94 is upregulat
Publikováno v:
Journal of Bioscience and Bioengineering.
Therapeutic antibodies are attractive biopharmaceuticals because of their high therapeutic effects, fewer side effects, and prolonged half-life in the blood. Chinese hamster ovary (CHO) cells are the most widely used host cell lines to produce therap
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Chinese hamster (Cricetulus griseus) ovary-derived Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for the industrial production of recombinant therapeutics because of their ability to fold, assemble, and perform post-tra
Publikováno v:
Cytotechnology. 71:193-207
Biopharmaceuticals represented by immunoglobulin G (IgG) are produced by the cultivation of recombinant animal cells, especially Chinese hamster ovary (CHO) cells. It is thought that the intracellular secretion process of IgG is a bottleneck in the p
Autor:
Yoshiki Nomura, Noriko Yamano-Adachi, Takeshi Omasa, Nako Okamoto, Masayoshi Onitsuka, Yuichi Koga, Hajime Enatsu
Publikováno v:
Journal of bioscience and bioengineering. 132(3)
Cartilaginous fishes such as sharks have adaptive immune systems based on immunoglobulins similar to those in mammals. During their evolution, cartilaginous fishes individually have acquired their adaptive immune system called immunoglobulin new anti
Publikováno v:
Journal of bioscience and bioengineering. 129(1)
Chromosomes in Chinese hamster ovary (CHO) cells are labile. We have shown that high-chromosome-number CHO cells have greater potential to become robust producers of recombinant proteins. One explanation being the increase in transgene integration si