Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Noriko Shimazu"'
Autor:
Kumiko Shiba, Kyoichiro Tsuchiya, Chikara Komiya, Yasutaka Miyachi, Kentaro Mori, Noriko Shimazu, Shinobu Yamaguchi, Naomi Ogasawara, Makoto Katoh, Michiko Itoh, Takayoshi Suganami, Yoshihiro Ogawa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Sodium glucose cotransporter 2 (SGLT2) inhibitors, an antidiabetic drug, promotes urinary excretion of glucose by blocking its reabsorption in the renal proximal tubules. It is unclear whether SGLT2 inhibition could attenuate nonalcoholic st
Externí odkaz:
https://doaj.org/article/f40c5869250d4118846a58308f7da1f5
Autor:
Yasutaka Miyachi, Kyoichiro Tsuchiya, Chikara Komiya, Kumiko Shiba, Noriko Shimazu, Shinobu Yamaguchi, Michiyo Deushi, Mizuko Osaka, Kouji Inoue, Yuta Sato, Sayaka Matsumoto, Junichi Kikuta, Kenjiro Wake, Masayuki Yoshida, Masaru Ishii, Yoshihiro Ogawa
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2766-2779 (2017)
Obesity promotes infiltration of inflammatory cells into various tissues, leading to parenchymal and stromal cell interaction and development of cellular and organ dysfunction. Liver sinusoidal endothelial cells (LSECs) are the first cells that conta
Externí odkaz:
https://doaj.org/article/e33dfdfd143c4d5699fe6ff694e6f159
Autor:
Chikara Komiya, Kyoichiro Tsuchiya, Kumiko Shiba, Yasutaka Miyachi, Shunsaku Furuke, Noriko Shimazu, Shinobu Yamaguchi, Kazuo Kanno, Yoshihiro Ogawa
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151511 (2016)
Type 2 diabetes mellitus (T2DM) is associated with a high incidence of non-alcoholic fatty liver disease (NAFLD) related to obesity and insulin resistance. Currently, medical interventions for NAFLD have focused on diet control and exercise to reduce
Externí odkaz:
https://doaj.org/article/d9fd0a9ca395419490df61270b087009
Autor:
Masayuki Yoshida, Kenjiro Wake, Masaru Ishii, Junichi Kikuta, Sayaka Matsumoto, Mizuko Osaka, Kouji Inoue, Yoshihiro Ogawa, Kumiko Shiba, Kyoichiro Tsuchiya, Chikara Komiya, Yasutaka Miyachi, Michiyo Deushi, Noriko Shimazu, Shinobu Yamaguchi, Yuta Sato
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2766-2779 (2017)
Obesity promotes infiltration of inflammatory cells into various tissues, leading to parenchymal and stromal cell interaction and development of cellular and organ dysfunction. Liver sinusoidal endothelial cells (LSECs) are the first cells that conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ba486f4cbd81df03486bf699492068
http://www.sciencedirect.com/science/article/pii/S2211124717302371
http://www.sciencedirect.com/science/article/pii/S2211124717302371
Autor:
Naomi Ogasawara, Kyoichiro Tsuchiya, Yasutaka Miyachi, Kumiko Shiba, Kentaro Mori, Chikara Komiya, Noriko Shimazu, Takayoshi Suganami, Makoto Katoh, Yoshihiro Ogawa, Michiko Itoh, Shinobu Yamaguchi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Sodium glucose cotransporter 2 (SGLT2) inhibitors, an antidiabetic drug, promotes urinary excretion of glucose by blocking its reabsorption in the renal proximal tubules. It is unclear whether SGLT2 inhibition could attenuate nonalcoholic steatohepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904b2c39bea895f37e93e3d9324326b5
https://pubmed.ncbi.nlm.nih.gov/29402900
https://pubmed.ncbi.nlm.nih.gov/29402900
Autor:
Kentaro Mori, Yasutaka Miyachi, Kyoichiro Tsuchiya, Miyako Tanaka, Kozue Ochi, Shunsaku Furuke, Kazuhiko Nakabayashi, Noriko Shimazu, Kenji Ikeda, Takayoshi Suganami, Chikara Komiya, Michiko Itoh, Yoshihiro Ogawa, Kumiko Shiba, Ken Ichiro Hata, Shinobu Yamaguchi
Publikováno v:
Scientific Reports
Non-alcoholic steatohepatitis (NASH) is characterized by steatosis with lobular inflammation and hepatocyte injury. Pirfenidone (PFD) is an orally bioavailable pyridone derivative that has been clinically used for the treatment of idiopathic pulmonar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46fd3907abe800d16b6efcf845795e9
https://doi.org/10.1038/srep44754
https://doi.org/10.1038/srep44754
Publikováno v:
The Journal of Cell Biology
By interacting with the collagen cargo receptor component cTAGE5, Sec12 concentrates at ER exit sites and generates the high levels of GTP-bound Sar1 necessary for export of collagen to the Golgi.
Mechanisms for exporting variably sized cargo fr
Mechanisms for exporting variably sized cargo fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf55f2f5ff2d83059ee7300ccb82601
https://doi.org/10.1083/jcb.201312062
https://doi.org/10.1083/jcb.201312062
Autor:
Kazuo Kanno, Noriko Shimazu, Chikara Komiya, Kumiko Shiba, Shunsaku Furuke, Shinobu Yamaguchi, Kyoichiro Tsuchiya, Yoshihiro Ogawa, Yasutaka Miyachi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0151511 (2016)
PLoS ONE, Vol 11, Iss 3, p e0151511 (2016)
Type 2 diabetes mellitus (T2DM) is associated with a high incidence of non-alcoholic fatty liver disease (NAFLD) related to obesity and insulin resistance. Currently, medical interventions for NAFLD have focused on diet control and exercise to reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d915e3650d011d173ddb9665af9a66
https://pubmed.ncbi.nlm.nih.gov/26977813
https://pubmed.ncbi.nlm.nih.gov/26977813
Autor:
Noriko Shimazu, Mieko Koitabashi, Michie Kurabe, Eriha Dekura, Wataru Toriumi, Hisako Fujimura
Publikováno v:
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 58(6)
To evaluate new-drugs potential for phospholipidosis (PL), we developed a cell-based fluorescence assay using a fluorescent-labeled phospholipid analogue (NBD-PE). CHL/IU cells derived from newborn hamster lung were exposed to positive reference comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b454edc3355a055501a18b2ea83ac72
https://pubmed.ncbi.nlm.nih.gov/17408938
https://pubmed.ncbi.nlm.nih.gov/17408938
Publikováno v:
Scopus-Elsevier
We have developed a photo-cross-linked oligonucleotide (clip-ODN) for a novel type of gene regulator molecule. Here, we examined the ability of the clip-ODN as a decoy DNA on regulation of the transcriptional activity of estrogen receptor (ER). A pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5aa2a650b3cf1b32d5b9da2de9411e
https://doi.org/10.1093/nass/nrm046
https://doi.org/10.1093/nass/nrm046