Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Noriko Ogiku"'
Autor:
Toshiaki Imagawa, Munekazu Shigekawa, Takeshi Matsumoto, Ichiro Obi, Kazuhiko Saeki, Noriko Ogiku
Publikováno v:
Life Sciences. 70:2377-2389
The clinical use of doxorubicin, an antineoplasmic agent, is limited by its extensive cardiotoxicity which is mediated by the mobilization of intracellular Ca2+ from SR. In order to elucidate the mechanism of Ca2+ release, we analyzed the binding sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b32f4730fa8b7646a0996a014d508e6
https://doi.org/10.1016/s0024-3205(02)01524-2
https://doi.org/10.1016/s0024-3205(02)01524-2
Autor:
Ichiro Obi, Noriko Ogiku, Munekazu Shigekawa, Takeshi Matsumoto, Kazuhiko Saeki, Toshiaki Imagawa
Publikováno v:
Japanese Journal of Pharmacology. 89:21-28
We determined the effect of 9-hydroxyellipticine (9HE) on ryanodine receptor (RyR) and cardiac function after global ischemia in isolated rat hearts. The binding of [3H]-ryanodine in rabbit cardiac sarcoplasmic reticulum was displaced by 9HE in a bip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb55624b5cf5593a6ba9b2a5f9b97bb3
https://doi.org/10.1254/jjp.89.21
https://doi.org/10.1254/jjp.89.21
Publikováno v:
Life Sciences. 63:575-588
To clarify a function of brain-type ryanodine receptor (RyR3) and its regulation, we established a stable cell line expressing rabbit RyR3 by transfection of Chinese hamster ovary cells (CHO cells) with the cDNA and investigated characteristics of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42093485b5f087c5b4fdb0ceb9dd863d
https://doi.org/10.1016/s0024-3205(98)00308-7
https://doi.org/10.1016/s0024-3205(98)00308-7
Publikováno v:
Japanese Journal of Pharmacology. 66:231-240
Our previous studies showed that imidapril prevented the occurrence of cerebral stroke and ameliorated biochemical parameter changes of renal dysfunction at a dose that did not inhibit the progression of hypertension in salt-loaded stroke-prone spont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0d8acde3edc00d178edf120f075f7d
https://doi.org/10.1254/jjp.66.231
https://doi.org/10.1254/jjp.66.231
Publikováno v:
Japanese Journal of Pharmacology. 64:129-133
For this study, we used (NZW x BXSB)F1 male mice as a model of myocardial infarction. The animals were kept on water containing imidapril or enalapril at 60 mg/kg/day from 10 to 27 weeks of age. Imidapril and enalapril significantly reduced the blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf15f7703c9f881da903de04e0cb1b0
https://doi.org/10.1254/jjp.64.129
https://doi.org/10.1254/jjp.64.129
Publikováno v:
Japanese Journal of Pharmacology. 61:69-73
Many of the disorders in urinary, biochemical, and hematological parameters induced by salt-loading in stroke-prone spontaneously hypertensive rats (SHRSP) were significantly ameliorated by chronic treatment with angiotensin converting enzyme inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3278111c809167127874d6f4ffbac97d
https://doi.org/10.1254/jjp.61.69
https://doi.org/10.1254/jjp.61.69
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 19(3)
Effects of isoproterenol (ISO) on the expression of cardiac angiotensinogen mRNA, angiotensin converting enzyme (ACE) activity, and mechanical functions in spontaneously hypertensive rats were investigated. In the acute phase, defined as within 24h a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea46194e2b5332e8ed22bbd3270eb7f
https://pubmed.ncbi.nlm.nih.gov/8891746
https://pubmed.ncbi.nlm.nih.gov/8891746
Autor:
Noriko Ogiku, Yasushi Ohmachi, Hisayoshi Doi, Hideo Yabana, Hideo Kurosawa, Hiroshi Narita, Minako Kaburaki
Publikováno v:
Journal of cardiovascular pharmacology. 27(6)
We studied the effect of imidapril, a novel angiotensin-converting enzyme (ACE) inhibitor, on lifespan expectancy of cardiomyopathic (CM) hamsters of BIO 14.6 strain, one of the representative models of congestive heart failure (CHF). Imidapril was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cb14f0870d887ef8e547ae608d101d
https://pubmed.ncbi.nlm.nih.gov/8761854
https://pubmed.ncbi.nlm.nih.gov/8761854
Publikováno v:
Japanese journal of pharmacology. 63(3)
To investigate the involvement of the sympathoinhibitory effect of imidapril and enalapril in their antihypertensive effect at a clinically reasonable dose, we studied whether some responses induced by the stimulation of the sympathetic nervous syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c954d4c5c226c1b826f9e10838b38ece
https://pubmed.ncbi.nlm.nih.gov/7906318
https://pubmed.ncbi.nlm.nih.gov/7906318