Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Noriko Mochizuki"'
Autor:
Shigeru Miyagawa, Takuji Kawamura, Emiko Ito, Maki Takeda, Hiroko Iseoka, Junya Yokoyama, Akima Harada, Noriko Mochizuki-Oda, Yukiko Imanishi-Ochi, Junjun Li, Masao Sasai, Fumiyo Kitaoka, Masaki Nomura, Naoki Amano, Tomoko Takahashi, Hiromi Dohi, Eiichi Morii, Yoshiki Sawa
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Cell- or tissue-based regenerative therapy is an attractive approach to treat heart failure. A tissue patch that can safely and effectively repair damaged heart muscle would greatly improve outcomes for patients with heart failure
Externí odkaz:
https://doaj.org/article/dfacd8d29b3c4351b45788ad52a5a5a6
Autor:
Emiko Ito, Ai Kawamura, Takuji Kawamura, Maki Takeda, Akima Harada, Noriko Mochizuki-Oda, Yoshiki Sawa, Shigeru Miyagawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Transplantation of human allogeneic induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is a new, promising treatment for severe heart failure. However, immunorejection is a significant concern in allogeneic hiPSC-CM transplanta
Externí odkaz:
https://doaj.org/article/8496e5b404b348449c3bd176809a8d59
Autor:
Takuji Kawamura, Yoshito Ito, Emiko Ito, Maki Takeda, Tsubasa Mikami, Takura Taguchi, Noriko Mochizuki-Oda, Masao Sasai, Tomomi Shimamoto, Yukako Nitta, Daisuke Yoshioka, Masashi Kawamura, Ai Kawamura, Yusuke Misumi, Yasushi Sakata, Yoshiki Sawa, Shigeru Miyagawa
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionWith the expected increase in patients with heart failure and ischemic 15 cardiomyopathy, the development of myocardial regenerative medicine using cell transplantation as a novel treatment method is progressing. This first-in-human clini
Externí odkaz:
https://doaj.org/article/b379e93a15b64639a60a5e19e47d00a1
Autor:
Nagako Sougawa, Shigeru Miyagawa, Takuji Kawamura, Ryohei Matsuura, Akima Harada, Yoshiki Sakai, Noriko Mochizuki-Oda, Ryoko Sato-Nishiuchi, Kiyotoshi Sekiguchi, Yoshiki Sawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Although endogenous cardiac repair by recruitment of stem cells may serve as a therapeutic approach to healing a damaged heart, how to effectively enhance the migration of stem cells to the damaged heart is unclear. Here, we examined whether
Externí odkaz:
https://doaj.org/article/d5eab8b2b872415c8dba102b5032a1ae
Autor:
Shigeru Miyagawa, Satoshi Kainuma, Takuji Kawamura, Kota Suzuki, Yoshito Ito, Hiroko Iseoka, Emiko Ito, Maki Takeda, Masao Sasai, Noriko Mochizuki-Oda, Tomomi Shimamoto, Yukako Nitta, Hiromi Dohi, Tadashi Watabe, Yasushi Sakata, Koichi Toda, Yoshiki Sawa
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Despite major therapeutic advances, heart failure, as a non-communicable disease, remains a life-threatening disorder, with 26 million patients worldwide, causing more deaths than cancer. Therefore, novel strategies for the treatment of heart failure
Externí odkaz:
https://doaj.org/article/d2598ef6482f44ff824c95618be2a291
Autor:
Maki Takeda, Shigeru Miyagawa, Emiko Ito, Akima Harada, Noriko Mochizuki-Oda, Michiya Matsusaki, Mitsuru Akashi, Yoshiki Sawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract We hypothesized that an appropriate ratio of cardiomyocytes, fibroblasts, endothelial cells, and extracellular matrix (ECM) factors would be required for the development of three-dimensional cardiac tissues (3D-CTs) as drug screening systems
Externí odkaz:
https://doaj.org/article/e8d088719a1542128974b40335af742f
Autor:
Nagako Sougawa, Shigeru Miyagawa, Satsuki Fukushima, Ai Kawamura, Junya Yokoyama, Emiko Ito, Akima Harada, Kaori Okimoto, Noriko Mochizuki-Oda, Atsuhiro Saito, Yoshiki Sawa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Induced pluripotent stem cells (iPSCs) are promising candidate cells for cardiomyogenesis in the failing heart. However, teratoma/tumour formation originating from undifferentiated iPSCs contaminating the graft is a critical concern for clin
Externí odkaz:
https://doaj.org/article/cfdeec773a2748ad83c8286f15cb0fb6
Autor:
Akima Harada, Nagako Sougawa, Shigeru Miyagawa, Ryohei Matsuura, Noriko Mochizuki-Oda, Yoshiki Sakai, Yoshiki Sawa, Kiyotoshi Sekiguchi, Ryoko Sato-Nishiuchi, Takuji Kawamura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Although endogenous cardiac repair by recruitment of stem cells may serve as a therapeutic approach to healing a damaged heart, how to effectively enhance the migration of stem cells to the damaged heart is unclear. Here, we examined whether the comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ab2b70f1c079cd2916a606c92a7d35
https://doaj.org/article/d5eab8b2b872415c8dba102b5032a1ae
https://doaj.org/article/d5eab8b2b872415c8dba102b5032a1ae
Autor:
Noriko Mochizuki-Oda, Kazumasa Minami, Shigeru Miyagawa, Emiko Ito, Yoshiki Sawa, Maki Takeda, Akima Harada
Publikováno v:
Biochemical and Biophysical Research Communications. 574:91-96
A major concern in the clinical application of induced pluripotent stem cells (iPSCs) is the prevention of tumorigenesis after implantation. Stem cells with high proliferative and differentiation potential are sensitive to radiation. Therefore, we hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b4881bafa6e80bae268e19881fd5c0
https://doi.org/10.1016/j.bbrc.2021.08.065
https://doi.org/10.1016/j.bbrc.2021.08.065
Autor:
Shigeru Miyagawa, Satoshi Kainuma, Takuji Kawamura, Kota Suzuki, Yoshito Ito, Hiroko Iseoka, Emiko Ito, Maki Takeda, Masao Sasai, Noriko Mochizuki-Oda, Tomomi Shimamoto, Yukako Nitta, Hiromi Dohi, Tadashi Watabe, Yasushi Sakata, Koichi Toda, Yoshiki Sawa
BackgroundDespite major therapeutic advances, heart failure remains a life-threatening disorder, with 26 million patients worldwide, causing more deaths than cancer as a non-communicable disease. Therefore, novel strategies for the treatment of heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a620efc971a223fef49ef45f027a8bde
https://doi.org/10.1101/2021.12.27.21268295
https://doi.org/10.1101/2021.12.27.21268295
