Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Noriko Komatsu"'
Autor:
Tokuju Okano, Hiroshi Ashida, Noriko Komatsu, Masayuki Tsukasaki, Tamako Iida, Marie Iwasawa, Yuto Takahashi, Yasuo Takeuchi, Takanori Iwata, Miwa Sasai, Masahiro Yamamoto, Hiroshi Takayanagi, Toshihiko Suzuki
Publikováno v:
International Journal of Oral Science, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Clinical studies have shown that Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) is associated with aggressive periodontitis and can potentially trigger or exacerbate rheumatoid arthritis (RA). However, the mechanism is poor
Externí odkaz:
https://doaj.org/article/dcc49346b1834b0b8905fe5ed7f09f4d
Autor:
Nam Cong-Nhat Huynh, Rui Ling, Masatsugu Komagamine, Tianshu Shi, Masayuki Tsukasaki, Kotaro Matsuda, Kazuo Okamoto, Tatsuo Asano, Ryunosuke Muro, Warunee Pluemsakunthai, George Kollias, Yuko Kaneko, Tsutomu Takeuchi, Sakae Tanaka, Noriko Komatsu, Hiroshi Takayanagi
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-18 (2024)
Abstract Background Recent single-cell RNA sequencing (scRNA-seq) analysis revealed the functional heterogeneity and pathogenic cell subsets in immune cells, synovial fibroblasts and bone cells in rheumatoid arthritis (RA). JAK inhibitors which ameli
Externí odkaz:
https://doaj.org/article/ea3736b484c44dd68e91bd945e1b9dbe
Autor:
Yutaro Ando, Masayuki Tsukasaki, Nam Cong-Nhat Huynh, Shizao Zang, Minglu Yan, Ryunosuke Muro, Kazutaka Nakamura, Masatsugu Komagamine, Noriko Komatsu, Kazuo Okamoto, Kenta Nakano, Tadashi Okamura, Akira Yamaguchi, Kazuyuki Ishihara, Hiroshi Takayanagi
Publikováno v:
International Journal of Oral Science, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract The immune-stromal cell interactions play a key role in health and diseases. In periodontitis, the most prevalent infectious disease in humans, immune cells accumulate in the oral mucosa and promote bone destruction by inducing receptor acti
Externí odkaz:
https://doaj.org/article/ef68d310d1a64d4c82fa538d60156728
Autor:
Masatsugu Komagamine, Noriko Komatsu, Rui Ling, Kazuo Okamoto, Shi Tianshu, Kotaro Matsuda, Tsutomu Takeuchi, Yuko Kaneko, Hiroshi Takayanagi
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-14 (2023)
Abstract Background The types of bone damage in rheumatoid arthritis (RA) include joint erosion, periarticular osteoporosis, and systemic osteoporosis. Janus kinase (JAK) inhibitors ameliorate inflammation and joint erosion in RA, but their effect on
Externí odkaz:
https://doaj.org/article/d2dde201594e419d8b474911715267a4
Autor:
Minglu Yan, Masayuki Tsukasaki, Ryunosuke Muro, Yutaro Ando, Kazutaka Nakamura, Noriko Komatsu, Takeshi Nitta, Tadashi Okamura, Kazuo Okamoto, Hiroshi Takayanagi
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract The bony skeleton is continuously renewed throughout adult life by the bone remodeling process, in which old or damaged bone is removed by osteoclasts via largely unknown mechanisms. Osteocytes regulate bone remodeling by producing the osteo
Externí odkaz:
https://doaj.org/article/a84accbec20048e48a0b1505927f768f
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 973 (2024)
Background: Photodynamic therapy (PDT) is a cancer-targeted treatment that uses a photosensitizer (PS) and irradiation of a specific wavelength to exert cytotoxic effects. To enhance the antitumor effect against head and neck squamous cell carcinoma
Externí odkaz:
https://doaj.org/article/efdd13239dda42a0abae7b5d8de95bee
Autor:
Masayuki Tsukasaki, Noriko Komatsu, Takako Negishi-Koga, Nam Cong-Nhat Huynh, Ryunosuke Muro, Yutaro Ando, Yuka Seki, Asuka Terashima, Warunee Pluemsakunthai, Takeshi Nitta, Takashi Nakamura, Tomoki Nakashima, Shinsuke Ohba, Haruhiko Akiyama, Kazuo Okamoto, Roland Baron, Hiroshi Takayanagi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Intramembranous and endochondral bone formation have been considered to be independent processes mediated by independent stem cells. Here the authors show that periosteal stem cells participate in both types of bone formation, supporting endochondral
Externí odkaz:
https://doaj.org/article/84b0cf37270643d4a190d9226bc66f24
Autor:
Masanori Maeda, Miyuki Kadokura, Ryoko Aoki, Noriko Komatsu, Masaru Kawakami, Yuya Koyama, Kazuhiro Watanabe, Michiko Nishiyama
Publikováno v:
Sensors, Vol 23, Iss 4, p 2355 (2023)
We developed a wearable swallowing assessment device using a hetero-core fiber-optic pressure sensor for the detection of laryngeal movement during swallowing. The proposed pressure sensor (comfortably attached to the skin of the neck) demonstrated a
Externí odkaz:
https://doaj.org/article/8ae53d3904e24fa880f812a2724968a2
Autor:
Daisuke Takahashi, Naomi Hoshina, Yuma Kabumoto, Yuichi Maeda, Akari Suzuki, Hiyori Tanabe, Junya Isobe, Takahiro Yamada, Kisara Muroi, Yuto Yanagisawa, Atsuo Nakamura, Yumiko Fujimura, Aiko Saeki, Mizuki Ueda, Ryohtaroh Matsumoto, Hanako Asaoka, Julie M. Clarke, Yohsuke Harada, Eiji Umemoto, Noriko Komatsu, Takaharu Okada, Hiroshi Takayanagi, Kiyoshi Takeda, Michio Tomura, Koji Hase
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102913- (2020)
Background: Rheumatoid arthritis (RA) is a chronic debilitating autoimmune disorder with a high prevalence, especially in industrialized countries. Dysbiosis of the intestinal microbiota has been observed in RA patients. For instance, new-onset untre
Externí odkaz:
https://doaj.org/article/1f63ab6004a146fa8e8dd2e2492aca39
Autor:
Masayuki Tsukasaki, Noriko Komatsu, Kazuki Nagashima, Takeshi Nitta, Warunee Pluemsakunthai, Chisa Shukunami, Yoichiro Iwakura, Tomoki Nakashima, Kazuo Okamoto, Hiroshi Takayanagi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
IL-17-producing T cells are protective against infection, but the authors of this article previously showed that these cells also contribute to inflammatory bone destruction. Here they show in the context of periodontitis that microbiota-driven Th17-
Externí odkaz:
https://doaj.org/article/89c1ce4662c546e1b7232d546be96290