Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Noriko Kotobuki"'
Autor:
Noriko Kotobuki, Yoshihiro Katsube, Youichi Katou, Mika Tadokoro, Motohiro Hirose Ph.D., Hajime Ohgushi
Publikováno v:
Cell Transplantation, Vol 17 (2008)
Marrow mesenchymal stem cells (MSCs) are multipotent progenitor cells and reported to be immunoprivileged as well as immunosuppressive. Hence, MSCs might be ideal candidates for allogeneic transplantation to induce regeneration of damaged tissues/org
Externí odkaz:
https://doaj.org/article/05515502dd8647078eacc1cf7f48758f
Publikováno v:
Cell Transplantation, Vol 13 (2004)
In this article we describe the expansion of in vitro osteogenic capability of human osteoblasts (HOS cells) after sorting by fluorescence-activated cell sorting (FACS) with the osteoblastic marker of human bone alkaline phosphatase (AP) monoclonal a
Externí odkaz:
https://doaj.org/article/39ddd24e3b504f7ab353da0bf39fcb27
Autor:
Yu Kimura, Koji Hattori, Motohiro Hirose, Noriko Kotobuki, Mika Tadokoro, Asako Matsushima, Yasuhiko Tabata, Hajime Ohgushi
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 6:253-260
Bone marrow mesenchymal stem cells (MSCs) have been used for bone tissue engineering due to their osteogenic differentiation capability, but their application is controversial. To enhance their capability, we prepared biodegradable gelatin sponges in
Publikováno v:
Journal of Biomaterials Science, Polymer Edition. 22:2389-2406
Soft, transparent and mechanically tough nanocomposite (M-NC) films composed of poly(2-methoxyethyl acrylate) (PMEA) and inorganic clay (hectorite) were studied as substrates for a living cell harvest system. It was found that five cell types could a
Autor:
Junichi Sato, Takeshi Fukuchi, Hajime Ohgushi, Noriko Kotobuki, Mika Tadokoro, Kanichi Seto, Motohiro Hirose, Toshimitsu Tanaka
Publikováno v:
Journal of Biomedical Materials Research Part A. :428-435
Poly-lactic-glycolic acid (PLGA) is a biocompatible as well as biodegradable polymer and used in various medical applications. In this study, we evaluated efficiency of the specially designed three-dimensional porous PLGA as a scaffold for bone augme
Autor:
Noriko Kotobuki, Hajime Ohgushi, Hiroshi Yajima, Asako Matsushima, Kenji Kawate, Yoshinori Takakura, Mika Tadokoro
Publikováno v:
Artificial Organs. 33:474-481
The aim of the current study was to examine in vitro osteogenic capability and in vivo bone formation of mesenchymal stromal cells (MSCs) on two kinds of calcium phosphate ceramics. MSCs derived from human bone marrow were seeded on either hydroxyapa
Autor:
João F. Mano, Hajime Ohgushi, Alexandra P. Marques, Motohiro Hirose, Joaquim M. Oliveira, Johan Benesch, Noriko Kotobuki, Rui L. Reis, Rogério P. Pirraco, Silgia A. Costa
Publikováno v:
Advanced Functional Materials. 18:1840-1853
Novel highly branched biodegradable macromolecular systems have been developed by grafting carboxymethylchitosan (CMCht) onto low generation poly(amidoamine) (PAMAM) dendrimers. Such structures organize into sphere-like nanoparticles that are propose
Publikováno v:
Cell and Tissue Research. 332:279-288
To investigate the cascade of matrix mineralization, cells expressing high and low alkaline phosphatase (ALP) were separated from human osteoblast-like (HOS) cells by fluorescence-activated cell sorting with an ALP antibody. After these cells had bee
Publikováno v:
Key Engineering Materials. :1067-1070
Hydroxyapatite (HA) ceramics together with various kinds of osteogenic cells have been used in bone tissue engineering. It is well known that the ceramics structure and composition affect cell proliferation / differentiation. In this study, three dif
Autor:
Motohiro Hirose, Akifumi Iwama, Koji Ioku, Masaki Harada, Akira Sakaguchi, Hajime Ohgushi, Hiroshi Yamamoto, Noriko Kotobuki
Publikováno v:
Key Engineering Materials. :997-1000
Since 2001, we have clinically utilized human bone marrow-derived mesenchymal stem cells (MSCs) for bone regeneration. The osteogenic ability of MSCs has been assessed by measurement of alkaline phosphatase activity and calcium deposition. As for the