Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Noriki Iwai"'
Autor:
Noriki Iwai, Kotaro Akaki, Fabian Hia, Wei Li, Masanori Yoshinaga, Takashi Mino, Osamu Takeuchi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The ATP-dependent RNA helicase UPF1 plays a crucial role in various mRNA degradation pathways, most importantly in nonsense-mediated mRNA decay (NMD). Here, we show that UPF1 is upregulated during the early stages of B cell development and i
Externí odkaz:
https://doaj.org/article/4a18ea25ea8f464a96d19444bd27e11f
Autor:
Takeshi Tomita, Masayoshi Kato, Taishi Mishima, Yuta Matsunaga, Hideki Sanjo, Ken-ichi Ito, Kentaro Minagawa, Toshimitsu Matsui, Hiroyuki Oikawa, Satoshi Takahashi, Toshifumi Takao, Noriki Iwai, Takashi Mino, Osamu Takeuchi, Yoshiro Maru, Sachie Hiratsuka
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nonvesicular extracellular RNA (nex-RNA) that are not packed in extracellular vesicles is detected outside the cell, but it is poorly understood. Here the authors report that nex-RNA is captured by a zinc finger protein and transported to the nucleus
Externí odkaz:
https://doaj.org/article/a75fe0cb0a7242eda55465abbb5ce4d8
Autor:
Kotaro Akaki, Kosuke Ogata, Yuhei Yamauchi, Noriki Iwai, Ka Man Tse, Fabian Hia, Atsushi Mochizuki, Yasushi Ishihama, Takashi Mino, Osamu Takeuchi
Publikováno v:
eLife, Vol 10 (2021)
Regnase-1 is an endoribonuclease crucial for controlling inflammation by degrading mRNAs encoding cytokines and inflammatory mediators in mammals. However, it is unclear how Regnase-1-mediated mRNA decay is controlled in interleukin (IL)-1β- or Toll
Externí odkaz:
https://doaj.org/article/490cc825408948f287107aaec413dcb3
Autor:
Masayoshi Kato, Noriki Iwai, Sachie Hiratsuka, Taishi Mishima, Hideki Sanjo, Satoshi Takahashi, Ken ichi Ito, Yoshiro Maru, Toshimitsu Matsui, Osamu Takeuchi, Toshifumi Takao, Yuta Matsunaga, Takeshi Tomita, Hiroyuki Oikawa, Takashi Mino, Kentaro Minagawa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
RNA in extracellular vesicles (EVs) are uptaken by cells, where they regulate fundamental cellular functions. EV-derived mRNA in recipient cells can be translated. However, it is still elusive whether “naked nonvesicular extracellular mRNA” (nex-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacaa04621d042b9f6d8c26cc3248843
https://doaj.org/article/a75fe0cb0a7242eda55465abbb5ce4d8
https://doaj.org/article/a75fe0cb0a7242eda55465abbb5ce4d8
Autor:
Fabian Hia, Kosuke Ogata, Kotaro Akaki, Ka Man Tse, Osamu Takeuchi, Yasushi Ishihama, Yuhei Yamauchi, Noriki Iwai, Takashi Mino, Atsushi Mochizuki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::286862ee934717ccb52ae0edb7bee4a8
https://doi.org/10.7554/elife.71966.sa2
https://doi.org/10.7554/elife.71966.sa2
Autor:
Yuhei Yamauchi, Kosuke Ogata, Kotaro Akaki, Noriki Iwai, Fabian Hia, Atsushi Mochizuki, Takashi Mino, Yasushi Ishihama, Ka Man Tse, Osamu Takeuchi
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Regnase-1 is an endoribonuclease crucial for controlling inflammation by degrading mRNAs encoding cytokines and inflammatory mediators in mammals. However, it is unclear how Regnase-1-mediated mRNA decay is controlled in interleukin (IL)-1β- or Toll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0e1be6141e4ef373e40625922307c1
https://doi.org/10.1101/2021.07.15.452458
https://doi.org/10.1101/2021.07.15.452458
Autor:
Tomoko Emura, Akio Yamashita, Kumi Hidaka, Osamu Takeuchi, Noriki Iwai, Kentaro Inoue, Hiroshi Sugiyama, Kotaro Akaki, Fabian Hia, Takuya Uehata, Mariko Okada-Hatakeyama, Shigeo Ohno, Takashi Mino, Masayuki Endo, Yutaka Suzuki, Daron M. Standley
Publikováno v:
Nucleic Acids Research
Regnase-1-mediated mRNA decay (RMD), in which inflammatory mRNAs harboring specific stem–loop structures are degraded, is a critical part of proper immune homeostasis. Prior to initial translation, Regnase-1 associates with target stem–loops but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c27730510f0097a2a1aa2d19043daf6
http://hdl.handle.net/2433/243190
http://hdl.handle.net/2433/243190