Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Norikazu TAMURA"'
Autor:
Mitsuyuki Shimada, Hiroshi Miki, Kouhei Asano, Masaki Ogino, Yoshihisa Nakada, Toshihiro Yamamoto, Hiroshi Yamaguchi, Minori Masago, Norikazu Tamura, Kazuko Aoki, Koki Kato
Publikováno v:
European Journal of Pharmacology. 640:243-249
Coenzyme A (CoA):diacylglycerol acyltransferase 1 (DGAT1) is 1 of the 2 known DGAT enzymes that catalyze the final and only committed step in triacylglycerol synthesis; this enzyme is considered to be a potential therapeutic target in metabolic disor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47d4c79196895bf4987370a7fa79251
https://doi.org/10.1016/j.ejphar.2010.04.050
https://doi.org/10.1016/j.ejphar.2010.04.050
Autor:
Yoshihisa Nakada, Minori Masago, Mitsuyuki Shimada, Toshihiro Yamamoto, Kouhei Asano, Kazuko Aoki, Hiroshi Miki, Norikazu Tamura, Koki Kato, Masaki Ogino
Publikováno v:
Chemical and Pharmaceutical Bulletin. 58:673-679
In a program to discover new small molecule diacylglycerol acyltransferase (DGAT)-1 inhibitors, screening of our in-house chemical library was carried out using recombinant human DGAT-1 enzyme. From this library, the lead compound 1a was identified a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290ff49f8f9e87b4a037af867ededf87
https://doi.org/10.1248/cpb.58.673
https://doi.org/10.1248/cpb.58.673
Publikováno v:
Journal of Materials Synthesis and Processing. 9:153-163
In the present paper, by using a mathematical model for self-propagating high-temperature synthesis, we reveal the three-dimensional structure of so-called spin combustion wave on the inside of cylindrical sample. It is shown that an isothermal surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eef07e9f50d5547047d5b23520b8647c
https://doi.org/10.1023/a:1013201631587
https://doi.org/10.1023/a:1013201631587
Autor:
Tomoyuki Kitazaki, Katsumi Itoh, Ryogo Hayashi, Norikazu Tamura, Hiroshi Hosono, Yoshihiro Matsushita, Kenji Okonogi, Akihiro Tasaka
Publikováno v:
Chemical and Pharmaceutical Bulletin. 47:351-359
New optically active antifungal azoles, 1-[(1R,2R)-2-(2,4-difluoro- and 2-fluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl ]-3-(4- substituted phenyl)-2(1H,3H)-imidazolones (1,2) and 2-imidazolidinones (3,4), were prepared in a stereo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7ceb1a187f3b7869789ce047f05621
https://doi.org/10.1248/cpb.47.351
https://doi.org/10.1248/cpb.47.351
Publikováno v:
KOBUNSHI RONBUNSHU. 55:38-46
ガラス領域のポリメチルメタクリレート (PMMA) 中に分散させたフォトクロミック分子9-hydroxymethyl-10- { (1-naphthyl methoxy) methyl} anthracene (HNMA) に365nmの直線偏光を照射するとHNMAの分子内光二量
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9bc3ef9b7e32aaf47f729c870bca3d3
https://doi.org/10.1295/koron.55.38
https://doi.org/10.1295/koron.55.38
Autor:
Norikazu Tamura, Tomoyuki Kitazaki, Ryogo Hayashi, Katsumi Itoh, Kenji Okonogi, Yoshihiro Matsushita, Akihiro Tasaka
Publikováno v:
Chemical and Pharmaceutical Bulletin. 44:314-327
A new series of optically active antifungal azoles, N-[(1R, 2R)-2-(2, 4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1, 2, 4-triazol-1-yl)propyl]-N'-(4-substituted phenyl)-3(2H, 4H)-1, 2, 4-triazolones (1, 2) and 5(1H, 4H)-tetrazolones (3), were prepared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e34390bb3a6cde8012ae5185666a9f
https://doi.org/10.1248/cpb.44.314
https://doi.org/10.1248/cpb.44.314
Autor:
Akihiro TASAKA, Katsunori TERANISHI, Yoshihiro MATSUSHITA, Norikazu TAMURA, Ryogo HAYASHI, Kenji OKONOGI, Katsumi ITOH
Publikováno v:
Chemical and Pharmaceutical Bulletin. 42:85-94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::782efa25c6e8551eb86c1b2288732a4f
https://doi.org/10.1248/cpb.42.85
https://doi.org/10.1248/cpb.42.85
Autor:
Katsumi Itoh, Kenji Okonogi, Akihiro Tasaka, Yoshihiro Matsushita, Norikazu Tamura, Ryogo Hayashi, Katsunori Teranishi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 41:1043-1048
In an effort to find potent antifungal agents, a variety of optically active triazole derivatives with a polysulfide structure, 3, 4 and 5, were prepared and evaluated for antifungal activity against Candida albicans in vitro and in vivo. The symmetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e691af50f8274549821ac29c04d7dd92
https://doi.org/10.1248/cpb.41.1043
https://doi.org/10.1248/cpb.41.1043
Autor:
Katsunori Teranishi, Norikazu Tamura, Katsumi Itoh, Yoshihiro Matsushita, Kenji Okonogi, Ryogo Hayashi, Akihiro Tasaka
Publikováno v:
Chemical and Pharmaceutical Bulletin. 41:1035-1042
(2R,3R)-2-(2,4-Difluorophenyl)-3-mercapto-1-(1H-1,2,4-triazol-1-yl )-2-butano l [(2R,3R)-7] and its stereoisomers [(2S,3R)-, (2S,3S)- and (2R,3S)-7] were prepared from the optically active oxiranes 6 by a newly developed ring-opening reaction and eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdacbc4c7ad90feb1f7414e1321fc601
https://doi.org/10.1248/cpb.41.1035
https://doi.org/10.1248/cpb.41.1035
Autor:
Kouhei Asano, Masaki Ogino, Toshihiro Yamamoto, Mitsuyuki Shimada, Norikazu Tamura, Kazuko Aoki, Yoshihisa Nakada, Hiroshi Miki, Minori Masago, Koki Kato
Publikováno v:
ChemInform. 41
A series of novel N-(substituted hetaryl)-4-aryl-4-oxobutanamides are designed, synthesis and evaluated for their activity against DGAT-1 enzyme.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec51c8607cf998bfb16eb107dd02fa21
https://doi.org/10.1002/chin.201043129
https://doi.org/10.1002/chin.201043129