Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Norikazu Saiki"'
Autor:
Tasuku Fujii, Yosuke Yoneyama, Akiko Kinebuchi, Naoki Ozeki, Sho Maeda, Norikazu Saiki, Toyofumi Fengshi Chen-Yoshikawa, Hiroshi Date, Kimitoshi Nishiwaki, Takanori Takebe
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106142- (2023)
Summary: The potential of extrapulmonary ventilation pathways remains largely unexplored. Here, we assessed the enteral ventilation approach in hypoxic porcine models under controlled mechanical ventilation. 20 mL/kg of oxygenated perfluorodecalin (O
Externí odkaz:
https://doaj.org/article/21e1f4c4fad140d1b00a1ff3f88217f8
Autor:
Kyle Lewis, Shodai Togo, Yosuke Yoneyama, Ran-Ran Zhang, Wendy Thompson, Rie Ouchi, Andrew Dunn, Hiroyuki Koike, Yuqi Cai, Autumn Ferguson, Akihiro Asai, Masaki Kimura, Mari Maezawa, Takanori Takebe, Norikazu Saiki, Tadahiro Shinozawa
Publikováno v:
Gastroenterology. 160(3)
Background & Aims Preclinical identification of compounds at risk of causing drug induced liver injury (DILI) remains a significant challenge in drug development, highlighting a need for a predictive human system to study complicated DILI mechanism a
Autor:
Fumiko Honda-Ozaki, Haruna Ito, Hongmei Lisa Li, Nobuo Kanazawa, Isao Asaka, Ayako Nagahashi, Tatsutoshi Nakahata, Fukumi Furukawa, Akitsu Hotta, Yuri Kawasaki, Megumu K. Saito, Masakatsu Yanagimachi, Norikazu Saiki, Koichi Igura, Madoka Terashima, Akira Niwa
Publikováno v:
Stem Cell Reports
Summary Nakajo-Nishimura syndrome (NNS) is an immunoproteasome-associated autoinflammatory disorder caused by a mutation of the PSMB8 gene. Although dysfunction of the immunoproteasome causes various cellular stresses attributed to the overproduction
Autor:
Norikazu Saiki, Tomoyoshi Soga, Ayako Nagahashi, Isao Asaka, Tatsutoshi Nakahata, Mitsujiro Osawa, Junichi Hara, Masaru Tomita, Yoshiro Kamachi, Akira Watanabe, Keisuke Okita, Shuichi Kitayama, Shin Kaneko, Wataru Fujibuchi, Akiyoshi Hirayama, Takafumi Noma, Shigeaki Nonoyama, Seiji Kojima, Koichi Oshima, Ayako Tanimura, Hiromasa Yabe, Akitsu Hotta, Akira Niwa, Michihiro Tanaka, Hiromi Imamura, Megumu K. Saito, Kohsuke Imai
Publikováno v:
Biochemical and Biophysical Research Communications. 497(2):719-725
AK2 is an adenylate phosphotransferase that localizes at the intermembrane spaces of the mitochondria, and its mutations cause a severe combined immunodeficiency with neutrophil maturation arrest named reticular dysgenesis (RD). Although the dysfunct
Autor:
Yo Mabuchi, Shoyo Hakozaki, Tadahiro Shinozawa, Patrick S. McGrath, Wendy Thompson, Shodai Togo, Yosuke Yoneyama, Takanori Takebe, Hiroyuki Koike, Norikazu Saiki, Christopher N. Mayhew, Rebekah Karns, Hiroshi Yoshikawa, Rie Ouchi, Ichiro Takeuchi, Masaki Kimura, Ran-Ran Zhang, Heather A. McCauley, Autumn Ferguson, James M. Wells, Kyle Lewis, Masaru Koido, Chihiro Akazawa
Publikováno v:
Cell metabolism. 30(2)
Summary Human organoid systems recapitulate in vivo organ architecture yet fail to capture complex pathologies such as inflammation and fibrosis. Here, using 11 different healthy and diseased pluripotent stem cell lines, we developed a reproducible m
Autor:
Norikazu Saiki, Akira Niwa, Emiko Yagi, Yukimasa Taniguchi, Ryo Ohta, Yoko Nishinaka-Arai, Megumu K. Saito, Tatsutoshi Nakahata, Junko Toga, Akira Watanabe, Chihiro Okada, Kiyotoshi Sekiguchi, Naoya M. Suzuki
Publikováno v:
Scientific Reports
Ohta, R. et al. Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells. Sci. Rep. 6, 35680; doi: 10.1038/srep35680 (2016)
Obtaining highly purified differentiated cells via directed differentiation from human pl
Obtaining highly purified differentiated cells via directed differentiation from human pl
Autor:
Koichi Oshima, Tomoyoshi Soga, Norikazu Saiki, Tatsutoshi Nakahata, Masaru Tomita, Megumu K. Saito, Akiyoshi Hirayama
Publikováno v:
Experimental Hematology. 43:S92