Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Norika Kashiwagi"'
Autor:
Yutaro Shiramasa, Ryu Yamamoto, Norika Kashiwagi, Fuka Sasaki, Sawaka Imai, Mikihito Ike, Soichiro Kitazawa, Tomoshi Kameda, Ryo Kitahara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Intracellular aggregation of fused in sarcoma (FUS) is associated with the pathogenesis of familial amyotrophic lateral sclerosis (ALS). Under stress, FUS forms liquid droplets via liquid–liquid phase separation (LLPS). Two types of wild-t
Externí odkaz:
https://doaj.org/article/040f8a8d75f8403595f3310bee45706c
Autor:
Shujie Li, Takuya Yoshizawa, Yutaro Shiramasa, Mako Kanamaru, Fumika Ide, Keiji Kitamura, Norika Kashiwagi, Naoya Sasahara, Soichiro Kitazawa, Ryo Kitahara
Publikováno v:
Physical chemistry chemical physics : PCCP. 24(32)
The liquid-to-solid phase transition of FUS liquid condensates were accelerated in the aberrant LLPS (HP-LLPS). Arginine, dopamine, and pyrocatechol suppress the formation of the aberrant LLPS more strongly than the normal LLPS (LP-LLPS).
Autor:
Shujie Li, Yutaro Shiramasa, Keiji Kitamura, Norika Kashiwagi, Soichiro Kitazawa, Ryo Kitahara
Publikováno v:
Biophysical Journal. 122:487a