Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Norihisa Masuyama"'
Autor:
Tomoyuki Fujiyama, Yo-ichi Nabeshima, Hiroyuki Hioki, Yukiko U. Inoue, Kunihiko Obata, Mami Terao, Norihisa Masuyama, Mikio Hoshino, Mayumi Yamada, Takayoshi Inoue, Toshio Terashima, Yuchio Yanagawa, Yoshiya Kawaguchi
Publikováno v:
Development. 136:2049-2058
The cochlear nucleus (CN), which consists of dorsal and ventral cochlear nuclei (DCN and VCN), plays pivotal roles in processing and relaying auditory information to the brain. Although it contains various types of neurons, the origins of the distinc
Publikováno v:
Journal of Biological Chemistry. 282:390-396
Neuronal precursors remain in the proliferative zone of the developing mammalian neocortex until after they have undergone neuronal differentiation and cell cycle arrest. The newborn neurons then migrate away from the proliferative zone and enter the
Autor:
Haruhiko Akiyama, Kei Hori, Schuichi Koizumi, Yusuke Seto, Noritaka Ichinohe, Tomoo Owa, Ryoya Hashimoto, Yukiko U. Inoue, Mikio Hoshino, Takayoshi Inoue, Ken-ichi Dewa, Norihisa Masuyama, Yoneko Hayase, Yoshiya Kawaguchi, Kazuhisa Sakai, Satoshi Miyashita
Publikováno v:
Mechanisms of development. 140
Development of oligodendrocytes, myelin-forming glia in the central nervous system (CNS), proceeds on a protracted schedule. Specification of oligodendrocyte progenitor cells (OPCs) begins early in development, whereas their terminal differentiation
Publikováno v:
The Journal of Cell Biology
Life and death decisions are made by integrating a variety of apoptotic and survival signals in mammalian cells. Therefore, there is likely to be a common mechanism that integrates multiple signals adjudicating between the alternatives. In this study
Autor:
Hiroshi Hanafusa, Norihisa Masuyama, Morioh Kusakabe, Hiroaki Yamanaka, Eisuke Nishida, Takayuki Yasunaga
Publikováno v:
Genes to Cells. 10:369-379
It has been suggested that ILK (integrin-linked kinase) participates in integrin- and growth factor-mediated signaling pathways and also functions as a scaffold protein at cell–extracellular matrix (ECM) adhesion sites. As the recently reported ILK
Autor:
Masato Nakafuku, Koji Oishi, Keisuke Kuida, Sachiko Kamakura, Yukiko Gotoh, Norihisa Masuyama, Takeshi Yoshimatsu, Yuko Isazawa
Publikováno v:
Developmental Biology. 276:172-184
During development of the mammalian brain, many neural precursor cells (NPCs) undergo apoptosis. The regulation of such cell death, however, is poorly understood. We now show that the survival of mouse embryonic NPCs in vitro was increased by culture
Autor:
Kazunori Nakajima, Yukiko Gotoh, Tetsu Akiyama, Norihisa Masuyama, Hidenori Tabata, Yusuke Hirabayashi, Yasuhiro Itoh
Publikováno v:
Development. 131:2791-2801
Neural precursor cells (NPCs) have the ability to self-renew and to give rise to neuronal and glial lineages. The fate decision of NPCs between proliferation and differentiation determines the number of differentiated cells and the size of each regio
Autor:
Masato Nakafuku, Sachiko Kamakura, Koji Oishi, Yukiko Gotoh, Norihisa Masuyama, Takeshi Yoshimatsu
Publikováno v:
Nature Cell Biology. 6:547-554
Although the Notch and JAK-STAT signalling pathways fulfill overlapping roles in growth and differentiation regulation, no coordination mechanism has been proposed to explain their relationship. Here we show that STAT3 is activated in the presence of
Publikováno v:
Genes to Cells. 8:657-669
Background: Previous studies have shown that phosphatidylinositol-3 kinase (PI3K) plays an important role in NGF (nerve growth factor)-induced neurite elongation. However, the roles of the PI3K pathway in neurite branch formation were not fully under
Autor:
Yukiko Gotoh, Kazuhiro Kishi, Lewis C. Cantley, Norihisa Masuyama, Hiroshi Shiota, Yousuke Ebina, Rie Matsushima, Takashi Katome, Toshiyuki Obata
Publikováno v:
Journal of Biological Chemistry. 278:28312-28323
Insulin plays a central role in the regulation of glucose homeostasis in part by stimulating glucose uptake and glycogen synthesis. The serine/threonine protein kinase Akt has been proposed to mediate insulin signaling in several processes. However,