Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Norihiro Shimokawa"'
Autor:
Daiki Setoyama, Takahiro A Kato, Ryota Hashimoto, Hiroshi Kunugi, Kotaro Hattori, Kohei Hayakawa, Mina Sato-Kasai, Norihiro Shimokawa, Sachie Kaneko, Sumiko Yoshida, Yu-Ichi Goto, Yuka Yasuda, Hidenaga Yamamori, Masahiro Ohgidani, Noriaki Sagata, Daisuke Miura, Dongchon Kang, Shigenobu Kanba
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0165267 (2016)
Evaluating the severity of depression (SOD), especially suicidal ideation (SI), is crucial in the treatment of not only patients with mood disorders but also psychiatric patients in general. SOD has been assessed on interviews such as the Hamilton Ra
Externí odkaz:
https://doaj.org/article/cd49b59643cd4d419c573988e8885cc5
Autor:
Motoki Watabe, Takahiro A Kato, Alan R Teo, Hideki Horikawa, Masaru Tateno, Kohei Hayakawa, Norihiro Shimokawa, Shigenobu Kanba
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120183 (2015)
Maladaptive social interaction and its related psychopathology have been highlighted in psychiatry especially among younger generations. In Japan, novel expressive forms of psychiatric phenomena such as "modern-type depression" and "hikikomori" (a sy
Externí odkaz:
https://doaj.org/article/70114f86337146849d79986c86ddc2e2
Autor:
Kohei Hayakawa, Motoki Watabe, Hideki Horikawa, Mina Sato-Kasai, Norihiro Shimokawa, Tomohiro Nakao, Takahiro A. Kato
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 2; Pages: 131
Lower serum levels of low-density lipoprotein cholesterol (LDL-C) have been suggested to indicate higher suicide risk and various psychiatric symptoms. Previously, we reported that lower serum LDL-C levels are associated with loneliness, social phobi
Autor:
Kohei Hayakawa, Ryoko Katsuki, Shinji Sakamoto, Mina Sato-Kasai, Takahiro A. Kato, Masaru Tateno, Norihiro Shimokawa, Hiroaki Kubo, Wakako Umene-Nakano, Dongchon Kang, Alan R. Teo, Nobuki Kuwano, Motoki Watabe, Daiki Setoyama, Shigenobu Kanba
Publikováno v:
Psychiatry and Clinical Neurosciences
Aim Understanding premorbid personality is important, especially when considering treatment selection. Historically, the premorbid personality of patients with major depression in Japan was described as Shuchaku-kishitsu [similar to Typus melancholic
Autor:
Kohei Hayakawa, Takahiro A. Kato, Mina Sato-Kasai, Alan R. Teo, Wakako Umene-Nakano, James E. Aikens, Norihiro Shimokawa, Jason I. Chen, Ryoko Katsuki, Shigenobu Kanba, Hiroaki Kubo
Publikováno v:
Psychiatry and Clinical Neurosciences
Aim Hikikomori, a form of severe social withdrawal, is an emerging issue in mental health, for which validated measurement tools are lacking. The object was to develop a self-report scale of hikikomori, and assess its psychometric properties and diag
Autor:
Dongchon Kang, Masahiro Ohgidani, Mina Sato-Kasai, Junji Kishimoto, Noriaki Sagata, Takahiro A. Kato, Kohei Hayakawa, Hiroaki Kubo, Shigenob Kanba, Norihiro Shimokawa, Daiki Setoyama, Nobuki Kuwano
Publikováno v:
Journal of Affective Disorders. 231:74-82
Background Early intervention in depression has been critical to prevent its negative impact including suicide. Recent blood biomarker studies for major depressive disorder (MDD) have suggested that tryptophan-kynurenine and lipid related metabolites
Autor:
Shiori Kato, Koko Ishizuka, Takeshi Nakahara, Mina Sato-Kasai, Ashley M. Wilson, Noriaki Sagata, Akira Sawa, Makiko Nakahara-Kido, Kohei Hayakawa, Masutaka Furue, Daiki Setoyama, Takahiro A. Kato, Nobuki Kuwano, Yasunari Sakai, Shigenobu Kanba, Norihiro Shimokawa, Shin Ichi Kano, Masahiro Ohgidani, Shouichi Ohga
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports
Scientific Reports
Direct conversion technique to produce induced-neuronal (iN) cells from human fibroblasts within 2 weeks is expected to discover unknown neuronal phenotypes of neuropsychiatric disorders. Here, we present unique gene expression profiles in iN cells f
Autor:
Mina Sato-Kasai, Shigenobu Kanba, Akira Monji, Yoshihiro Seki, Sota Kyuragi, Noriaki Sagata, Kohei Hayakawa, Yoshito Mizoguchi, Takahiro A. Kato, Shogo Inamine, Hideki Horikawa, Masahiro Ohgidani, Norihiro Shimokawa
Publikováno v:
Schizophrenia Research. 178:35-43
Viral infections during fetal and adolescent periods, as well as during the course of schizophrenia itself have been linked to the onset and/or relapse of a psychosis. We previously reported that the unique antipsychotic aripiprazole, a partial D2 ag
Autor:
Takeshi Sakurai, Masato Mitsuhashi, Mina Sato-Kasai, Norihiro Shimokawa, Noriaki Sagata, Nobuki Kuwano, Kohei Hayakawa, Takahiro A. Kato, Hiroaki Kubo, Masahiro Ohgidani, Shigenobu Kanba
Publikováno v:
Journal of affective disorders. 240
Background Neuroinflammation is suggested to be a crucial factor in the pathophysiology of major depressive disorder (MDD). Analysis of neuron-derived exosomes (NDE) in peripheral blood has recently been highlighted to reveal the pathophysiology of b
Publikováno v:
Journal of Neurochemistry. 115:606-613
We examined the effect of concanamycin A and bafilomycin A1, inhibitors of the vacuolar proton-ATPase, on maturation and expression of Ret, a tyrosine kinase receptor for glial cell line-derived neurotrophic factor. Ret appeared as 150- and 170-kDa b