Expressed glycosylphosphatidylinositol-anchored horseradish peroxidase identifies co-clustering molecules in individual lipid raft domains.

Autor: Arisa Miyagawa-Yamaguchi, Norihiro Kotani, Koichi Honke

Publikováno v: PLoS ONE, Vol 9, Iss 3, p e93054 (2014)

Lipid rafts that are enriched in glycosylphosphatidylinositol (GPI)-anchored proteins serve as a platform for important biological events. To elucidate the molecular mechanisms of these events, identification of co-clustering molecules in individual

Externí odkaz: https://doaj.org/article/9990bc6065794f9183324888b531aed5

Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins

Autor: Farhana Yesmin, Robiul H. Bhuiyan, Yuhsuke Ohmi, Satoko Yamamoto, Kei Kaneko, Yuki Ohkawa, Pu Zhang, Kazunori Hamamura, Nai-Kong V. Cheung, Norihiro Kotani, Koichi Honke, Tetsuya Okajima, Mariko Kambe, Orie Tajima, Keiko Furukawa, Koichi Furukawa

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 423, p 423 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 423
International Journal of Molecular Sciences

Gangliosides have been considered to modulate cell signals in the microdomain of the cell membrane, lipid/rafts, or glycolipid-enriched microdomain/rafts (GEM/rafts). In particular, cancer-associated gangliosides were reported to enhance the malignan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d101c7e495aaab8e86b2b0016b3c7a3
https://www.mdpi.com/1422-0067/23/1/423

Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis

Autor: Norihiro, Kotani, Takanari, Nakano, Ryusuke, Kuwahara

Publikováno v: Journal of Biological Chemistry. 298:102500

Coronavirus disease represents a real threat to the global population, and understanding the biological features of the causative virus, that is, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is imperative for mitigating this threat.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518386b6cc32092976e868fee5ee7b5f
https://doi.org/10.1016/j.jbc.2022.102500

Identification and characterization of splenic adherent cells forming densely‐packed colonies

Autor: Yosuke Mizuno, Yui Ida, Norihiro Kotani, Takayuki Murakoshi, Masataka Hirasaki, Akihiko Okuda

Publikováno v: Development, Growth & Differentiation. 61:283-293

It is thought that the spleen contains stem cells that differentiate into somatic cells other than immune cells. We investigated the presence of these hypothetical splenic cells with stem cell characteristics and identified adherent cells forming den

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c63fab7da5fc40beba41930cae5bc4
https://doi.org/10.1111/dgd.12605

Screening of candidate host cell membrane proteins involved in SARS-CoV-2 entry

Autor: Norihiro Kotani, Takanari Nakano, Ryusuke Kuwahara

Coronavirus disease (COVID-19) represents a real threat to the global population, and understanding the biological features of the causative virus, i.e., severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is imperative for mitigating this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34876937aaf9190ee1d82604e45a75e2
https://doi.org/10.1101/2020.09.09.289488