Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Norihiro, Imai"'
Autor:
Norihiro Imai, Yuki Ohsaki, Jinglei Cheng, Jingjing Zhang, Fumitaka Mizuno, Taku Tanaka, Shinya Yokoyama, Kenta Yamamoto, Takanori Ito, Yoji Ishizu, Takashi Honda, Masatoshi Ishigami, Hiroaki Wake, Hiroki Kawashima
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Lipid droplets (LDs) have been observed in the nuclei of hepatocytes; however, their significance in liver disease remains unresolved. Our purpose was to explore the pathophysiological features of intranuclear LDs in liver diseases. We inclu
Externí odkaz:
https://doaj.org/article/cbcdd40a7e6244acaa3c352ebdd6a8e6
Autor:
Kenta Yamamoto, Takashi Honda, Yosuke Inukai, Shinya Yokoyama, Takanori Ito, Norihiro Imai, Yoji Ishizu, Masanao Nakamura, Hiroki Kawashima
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 610 (2024)
We investigated the prognostic role of the gut microbiome and clinical factors in chronic liver disease (hepatitis, cirrhosis, and hepatocellular carcinoma [HCC]). Utilizing data from 227 patients whose stool samples were collected over the prior 3 y
Externí odkaz:
https://doaj.org/article/e53bec5a81254deba5733dc790a437d9
Autor:
Kenta Yamamoto, Yoji Ishizu, Takashi Honda, Takanori Ito, Norihiro Imai, Masanao Nakamura, Hiroki Kawashima, Yasuyuki Kitaura, Masatoshi Ishigami, Mitsuhiro Fujishiro
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Sarcopenia is thought to be related to the microbiome, but not enough reports in chronic liver disease (CLD) patients. In addition to the differences in microbiome, the role of the microbiome in the gut is also important to be clarified beca
Externí odkaz:
https://doaj.org/article/018c6c24b73a4d8fa16c123cb204976d
Autor:
Tetsuya Ishikawa, Yasuaki Tatsumi, Koichi Kato, Yumi Hayashi, Norihiro Imai, Takanori Ito, Yoji Ishizu, Masatoshi Ishigami, Wataru Nihei, Ayako Kato, Hisao Hayashi
Publikováno v:
Internal Medicine; 2024, Vol. 63 Issue 17, p2421-2425, 5p
Autor:
Hisanori Muto, Takanori Ito, Taku Tanaka, Shinya Yokoyama, Kenta Yamamoto, Norihiro Imai, Yoji Ishizu, Keiko Maeda, Takashi Honda, Tetsuya Ishikawa, Asuka Kato, Taichi Ohshiro, Fumiya Kano, Akihito Yamamoto, Kiyoshi Sakai, Hideharu Hibi, Masatoshi Ishigami, Mitsuhiro Fujishiro
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Non-alcoholic steatohepatitis (NASH) occurrence has been increasing and is becoming a major cause of liver cirrhosis and liver cancer. However, effective treatments for NASH are still lacking. We examined the benefits of serum-free condition
Externí odkaz:
https://doaj.org/article/bcd5f4a38ad5466e8f250c9d66651145
Autor:
Yue Li, Norihiro Imai, Hayley T. Nicholls, Blaine R. Roberts, Samaksh Goyal, Tibor I. Krisko, Lay-Hong Ang, Matthew C. Tillman, Anne M. Roberts, Mahnoor Baqai, Eric A. Ortlund, David E. Cohen, Susan J. Hagen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Cold exposure activates thermogenesis and fatty acid oxidation in brown fat, a process suppressed by Them1. Here, the authors show that cold induces Them1 phosphorylation and loss of puncta that suppress fatty acid use, leading to a diffuse localizat
Externí odkaz:
https://doaj.org/article/e474110267a740bcbae71a2b1885f9cd
Autor:
Hisanori Muto, Takashi Honda, Taku Tanaka, Shinya Yokoyama, Kenta Yamamoto, Takanori Ito, Norihiro Imai, Yoji Ishizu, Keiko Maeda, Tetsuya Ishikawa, Shungo Adachi, Chikara Sato, Noriko M. Tsuji, Masatoshi Ishigami, Mitsuhiro Fujishiro, Hiroki Kawashima
Publikováno v:
Nutrients, Vol 15, Iss 6, p 1473 (2023)
The impact of a high-fat diet (HFD) on intestinal permeability has been well established. When bacteria and their metabolites from the intestinal tract flow into the portal vein, inflammation in the liver is triggered. However, the exact mechanism be
Externí odkaz:
https://doaj.org/article/107a8e739783457f945caba04f203072
Autor:
Yosuke Inukai, Norihiro Imai, Kenta Yamamoto, Takanori Ito, Yoji Ishizu, Takashi Honda, Shuichi Okamoto, Takeshi Kanematsu, Nobuaki Suzuki, Tadashi Matsushita, Masatoshi Ishigami, Mitsuhiro Fujishiro
Publikováno v:
Annals of Hepatology, Vol 27, Iss 1, Pp 100545- (2022)
Introduction and objectives: Hepatitis C virus (HCV) infections in patients with hemophilia lead to the development of hepatocellular carcinoma (HCC) at a relatively younger age than that in patients without hemophilia. Although recent progress in di
Externí odkaz:
https://doaj.org/article/56d528cae306408094ab214136b36449
Autor:
Megan J. Ritter, Izuki Amano, Norihiro Imai, Lorraine Soares De Oliveira, Kristen R. Vella, Anthony N. Hollenberg
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101315- (2021)
Objective: The nuclear receptor corepressor 1 (NCOR1) and the silencing mediator of retinoic acid and thyroid hormone (SMRT, also known as NCOR2) play critical and specific roles in nuclear receptor action. NCOR1, both in vitro and in vivo specifical
Externí odkaz:
https://doaj.org/article/c6a08cde21e64194991ac12dd7bb2084
Autor:
Alfonso Rubio-Navarro, Nicolás Gómez-Banoy, Lisa Stoll, Friederike Dündar, Alex M. Mawla, Lunkun Ma, Eric Cortada, Paul Zumbo, Ang Li, Moritz Reiterer, Nathalia Montoya-Oviedo, Edwin A. Homan, Norihiro Imai, Ankit Gilani, Chengyang Liu, Ali Naji, Boris Yang, Angie Chi Nok Chong, David E. Cohen, Shuibing Chen, Jingli Cao, Geoffrey S. Pitt, Mark O. Huising, Doron Betel, James C. Lo
Publikováno v:
Nature Cell Biology. 25:565-578