Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Norihiro, Chatani"'
Autor:
Mayumi Egawa, Tomohide Kurahashi, Hidetoshi Eguchi, Satoshi Ogura, Yuichi Yoshida, Kunimaro Furuta, Takashi Kizu, Yoshihiro Kamada, Masaki Mori, Mina Hamano, Norihiro Chatani, Shinichi Kiso, Yuichiro Doki, Hayato Hikita, Tetsuo Takehara, Tomohide Tatsumi, Hiroaki Nagano
Publikováno v:
Hepatology Research. 47:1196-1205
AIM Forkhead Box M1 (FoxM1) is a proliferation-specific transcription factor. In this study, we aimed to elucidate the clinicopathological and prognostic values of FoxM1 expression in human hepatocellular carcinoma (HCC) and correlate FoxM1 expressio
Autor:
Yoshihiro Kamada, Norihiro Chatani, Shinichi Kiso, Mina Hamano, Takayo Takemura, Hisao Ezaki, Satoshi Ogura, Mayumi Egawa, Keigo Nishida, Kunimaro Furuta, Yoshikazu Nakaoka, Tetsuo Takehara, Yuichi Yoshida, Takashi Kizu
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 308:G613-G624
Grb2-associated binder 1 (Gab1) adaptor protein amplifies signals downstream of a broad range of growth factors/receptor tyrosine kinases. Although these signals are implicated in liver fibrogenesis, the role of Gab1 remains unclear. To elucidate the
Autor:
Yoshihiro Kamada, Mayumi Egawa, Norihiro Chatani, Satoshi Ogura, Yuichi Yoshida, Shinichi Kiso, Hisao Ezaki, Kunimaro Furuta, Akihiko Shimono, Takashi Kizu, Mina Hamano, Noriyuki Ouchi, Tetsuo Takehara
Publikováno v:
Liver International. 35:2017-2026
Background & Aims Obesity-related adipocytokine dysregulation is known to accelerate liver fibrosis progression. Recently, a natural Wnt5a inhibitor, secreted frizzled-related protein 5 (Sfrp5), was identified as a novel adipocytokine that has reduce
Autor:
Yoshihiro Kamada, Mayumi Egawa, Kunimaro Furuta, Mina Hamano, Shinichi Kiso, Norihiro Chatani, Hisao Ezaki, Yuichi Yoshida, Takashi Kizu, Tetsuo Takehara
Publikováno v:
Journal of Gastroenterology
Background and aim Impaired fatty liver regeneration has already been reported in many genetic modification models. However, in diet-induced simple hepatic steatosis, which showed similar phenotype with clinical pathology, whether liver regeneration
Autor:
Mayumi, Egawa, Yuichi, Yoshida, Satoshi, Ogura, Tomohide, Kurahashi, Takashi, Kizu, Kunimaro, Furuta, Yoshihiro, Kamada, Norihiro, Chatani, Mina, Hamano, Shinichi, Kiso, Hayato, Hikita, Tomohide, Tatsumi, Hidetoshi, Eguchi, Hiroaki, Nagano, Yuichiro, Doki, Masaki, Mori, Tetsuo, Takehara
Publikováno v:
Hepatology research : the official journal of the Japan Society of Hepatology. 47(11)
Forkhead Box M1 (FoxM1) is a proliferation-specific transcription factor. In this study, we aimed to elucidate the clinicopathological and prognostic values of FoxM1 expression in human hepatocellular carcinoma (HCC) and correlate FoxM1 expression wi
Autor:
Mayumi Egawa, Yoshihiro Kamada, Tetsuo Takehara, Takayo Takemura, Yuichi Yoshida, Takashi Kizu, Kunimaro Furuta, Hisao Ezaki, Norio Hayashi, Norihiro Chatani, Mina Hamano, Shinichi Kiso
Publikováno v:
Hepatology Research. 43:401-412
Aim Many studies indicate an accelerated progression of non-alcoholic steatohepatitis (NASH) in postmenopausal women. Very recently, we reported that estrogen deficiency enhanced the progression of steatohepatitis in mice fed a high fat and high chol
Autor:
Kunimaro Furuta, Shigeki Higashiyama, Yoshihiro Kamada, Yuichi Yoshida, Takashi Kizu, Yukiko Saji, Takayo Takemura, Hisao Ezaki, Norio Hayashi, Eisuke Mekada, Mina Hamano, Norihiro Chatani, Tetsuo Takehara, Shinichi Kiso, Ryo Iwamoto, Mayumi Egawa
Publikováno v:
Hepatology Research. 43:384-393
Aim: We previously demonstrated that heparin-binding epidermal growth factor-like growth factor (HB-EGF) is induced in response to several liver injuries. Because the HB-EGF knockout (KO) mice die in utero or immediately after birth due to cardiac de
Autor:
Yuji Matsuzawa, Norihiro Chatani, Mina Hamano, Kenji Watabe, Akira Yamada, Toshimitsu Hamasaki, Shusaku Tsutsui, Yoshihiro Kamada, Yoshifumi Tsukamoto, Kazuo Kinoshita, Takashi Fujimoto, Kunimaro Furuta, Norio Hayashi, Hisao Ezaki, Tetsuo Takehara, Shinichi Kiso, Osamu Kishida, Mayumi Egawa, Takayo Takemura, Miyuki Umeda, Yuichi Yoshida, Takashi Kizu, Aiko Furubayashi
Publikováno v:
Hepatology Research. 43:238-248
Aim: Central obesity, insulin resistance and alcohol consumption are thought to be major risk factors for fatty liver formation. Adiponectin (APN) prevents fatty liver formation, and its serum levels are lower in subjects with central obesity and/or
Autor:
Takayo Takemura, Yoshihiro Kamada, Yuichi Yoshida, Takashi Kizu, Norihiro Chatani, Mina Hamano, Shinichi Kiso, Norio Hayashi, Hisao Ezaki, Tetsuo Takehara, Mayumi Tsubakio
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 301:G1031-G1043
Recent studies indicate an accelerated progression of nonalcoholic steatohepatitis (NASH) in postmenopausal women. Hypercholesterolemia, an important risk factor for NASH progression, is often observed after menopause. This study examined the effects
Autor:
Kunimaro Furuta, Yoshihiro Kamada, Keigo Nishida, Norihiro Chatani, Mayumi Egawa, Tetsuo Takehara, Shinichiro Maeda, Shinichi Kiso, Yuichi Yoshida, Takashi Kizu, Tomohide Kurahashi, Satoshi Ogura, Yoshikazu Nakaoka
Publikováno v:
Hepatology (Baltimore, Md.). 63(4)
Acetaminophen (APAP) overdose is the leading cause of drug-induced acute liver failure. In APAP-induced acute liver failure, hepatocyte death and subsequent liver regeneration determines the prognosis of patients, making it necessary to identify suit