Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Norihiko Ohbayashi"'
Autor:
Norihiko Ohbayashi, Mitsunori Fukuda
Publikováno v:
F1000Research, Vol 9 (2020)
Melanin pigments are responsible for human skin and hair color, and they protect the body from harmful ultraviolet light. The black and brown melanin pigments are synthesized in specialized lysosome-related organelles called melanosomes in melanocyte
Externí odkaz:
https://doaj.org/article/6b0bf77e3c664bf5b2648d9ecc4ee393
Autor:
Michihiro Takahama, Mitsunori Fukuda, Norihiko Ohbayashi, Tatsuya Kozaki, Takuma Misawa, Toru Okamoto, Yoshiharu Matsuura, Shizuo Akira, Tatsuya Saitoh
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2944-2954 (2017)
Cyclic GMP-AMP synthase (cGAS) is a cytosolic DNA sensor that induces the IFN antiviral response. However, the regulatory mechanisms that mediate cGAS-triggered signaling have not been fully explored. Here, we show the involvement of a small GTPase,
Externí odkaz:
https://doaj.org/article/b3dd010512394109932e81b2181c56f3
Publikováno v:
Biology Open, Vol 4, Iss 3, Pp 267-275 (2015)
Varp (VPS9-ankyrin repeat protein) was originally identified as an activator of small GTPase Rab21 through its VPS9 domain, but it has subsequently been shown to function as a Rab32/38 effector through its first ANKR1 domain. Although these functions
Externí odkaz:
https://doaj.org/article/87e6667a534c4ab5ba9d62f5f1bc1200
Publikováno v:
Biology Open, Vol 3, Iss 9, Pp 803-814 (2014)
Small GTPase Rab35 is an important molecular switch for endocytic recycling that regulates various cellular processes, including cytokinesis, cell migration, and neurite outgrowth. We previously showed that active Rab35 promotes nerve growth factor (
Externí odkaz:
https://doaj.org/article/6a6c16b3c6e14cdea3a1475f2f63ca31
Autor:
Sanda Ljubicic, Paola Bezzi, Saska Brajkovic, Valeria Nesca, Claudiane Guay, Norihiko Ohbayashi, Mitsunori Fukuda, Amar Abderrahmani, Romano Regazzi
Publikováno v:
PLoS ONE, Vol 8, Iss 7 (2013)
Externí odkaz:
https://doaj.org/article/9e2f283bfb7f4e3e979ef4878c2f7487
Autor:
Sanda Ljubicic, Paola Bezzi, Saska Brajkovic, Valeria Nesca, Claudiane Guay, Norihiko Ohbayashi, Mitsunori Fukuda, Amar Abderrhamani, Romano Regazzi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68255 (2013)
Rab37 belongs to a subclass of Rab GTPases regulating exocytosis, including also Rab3a and Rab27a. Proteomic studies indicate that Rab37 is associated with insulin-containing large dense core granules of pancreatic β-cells. In agreement with these o
Externí odkaz:
https://doaj.org/article/00cbb79d31874e1283bd2989ec4ec076
Publikováno v:
Biochemical and Biophysical Research Communications. 528:220-226
Many plasma membrane proteins enter cells by clathrin-independent endocytosis (CIE). Rab family small GTPases play pivotal roles in CIE and following intracellular trafficking of cargo proteins. Here, we provide evidence that TBC1D24, which contains
Publikováno v:
The Journal of biological chemistry. 298(9)
Disordered expression and distribution of plasma membrane proteins at the cell surface leads to diverse malignant phenotypes in tumors, including cell invasion. The ubiquitin-specific protease TRE17/USP6, an oncogene identified in Ewing sarcoma, is h
Autor:
Yukino Ogura1,2, Norihiko Ohbayashi1, Yasunori Kanaho1,2 ykanaho@md.tsukuba.ac.jp, Atsushi Kawaguchi2 ats-kawaguchi@md.tsukuba.ac.jp, Yuji Funakoshi1,2 funa@md.tsukuba.ac.jp
Publikováno v:
Journal of Biological Chemistry. Sep2022, Vol. 298 Issue 9, p1-13. 13p.
Autor:
Yueh-Chien Lin, Yasunori Kanaho, Yuan-Li Huang, Yeong-Chin Jou, Chien-Chin Chen, Wei Min Chen, Hsinyu Lee, Cheng-Huang Shen, Norihiko Ohbayashi, Tang-Long Shen, Kuan-Ying Lu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1863:1305-1315
Lysophosphatidic acid (LPA) is a bioactive lipid growth factor which is present in high levels in serum and platelets. LPA binds to its specific G-protein-coupled receptors, including LPA1 to LPA6, thereby regulating various physiological functions,