Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Norihiko Kondo"'
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Cough is a major symptom in patients with asthma and poses a significant burden compared with other asthma symptoms. However, there are no approved treatments in Japan, developed to specifically treat cough in patients with asthma. We present the des
Externí odkaz:
https://doaj.org/article/457bd4aa7f4a4fbebd0ec7f86c9bb821
Autor:
Kazuhiko Uchiyama, Tomohisa Takagi, Yasunori Iwamoto, Norihiko Kondo, Tetsuya Okayama, Naohisa Yoshida, Kazuhiro Kamada, Kazuhiro Katada, Osamu Handa, Takeshi Ishikawa, Hiroaki Yasuda, Junichi Sakagami, Hideyuki Konishi, Nobuaki Yagi, Yuji Naito, Yoshito Itoh
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95080 (2014)
Background and aimsAzathioprine (AZA) is widely used for the treatment of inflammatory bowel disease (IBD) patients. AZA is catabolized by thiopurine S-methyltransferase (TPMT), which exhibits genetic polymorphisms. It has also been reported that 5-a
Externí odkaz:
https://doaj.org/article/bb1a37dcdfb54bc8bfafdf5d75194975
Publikováno v:
ERJ Open Research. 9:00452-2022
Cough is a major symptom in patients with asthma and poses a significant burden compared with other asthma symptoms. However, there are no approved treatments in Japan, developed to specifically treat cough in patients with asthma. We present the des
Autor:
Eiji Yoshihara, Yoshiyuki Matsuo, Yasuyuki Ishii, Junji Yodoi, Aoi Son, Hiroaki Okuyama, Tomonori Iyoda, Kayo Inaba, Hajime Nakamura, Wenrui Liu, Shinichi Oka, Norihiko Kondo, Hiroshi Masutani
Publikováno v:
European Journal of Immunology. 38:1358-1367
Thioredoxin-binding protein-2 (TBP-2), also known as vitamin D3-up-regulated protein 1 (VDUP1), was identified as an endogenous molecule interacting with thioredoxin (TRX). Here, we show that dendritic cells (DC) derived from TBP-2-deficient mice are
Publikováno v:
Antioxidants & Redox Signaling. 8:1881-1890
Oxidative stresses are largely mediated by intracellular protein oxidations by reactive oxygen species (ROS). Host cells are equipped with antioxidants that scavenge ROS. The cellular reduction/oxidation (redox) balance is maintained by ROS and antio
Autor:
Norihiko Kondo, Masaki Tanito, Akie Teratani, Yasuya Inomata, Hidenobu Tanihara, Hajime Nakamura, Junji Yodoi, Takahiro Kawaji
Publikováno v:
Journal of Neurochemistry. 98:372-385
Thioredoxin (TRX) plays a variety of redox-related roles in organisms. To investigate its function as an endogenous redox regulator in NMDA-induced retinal neurotoxicity, we injected NMDA with TRX, mutant TRX or saline into the vitreous cavity of rat
Autor:
Shinichi Oka, Kaimul Ahsan, Toru Yoshida, Junji Yodoi, Tomijiro Hara, Hajime Nakamura, Norihiko Kondo, Hiroshi Masutani
Publikováno v:
BioFactors. 27:47-51
Thioredoxin (TRX) binding protein-2 (TBP-2), a negative regulator of TRX, is involved in intracellular redox regulation and cellular growth. The expression of TBP-2 is frequently lost in tumor cell lines and tissues, whereas the ectopic expression of
Autor:
Junji Yodoi, Junichi Fujii, Norihiko Kondo, Masaki Tanito, Hajime Nakamura, Yong-Won Kwon, Jie Bai, Akihiro Ohira, Hiroshi Masutani
Publikováno v:
JOURNAL OF NEUROSCIENCE. 25(9):2396-2404
Exposure to excessive light induces retinal photoreceptor cell damage, leading to development and progression of various retinal diseases. We tested the effect of geranylgeranylacetone (GGA), an acyclic polyisoprenoid, on light-induced retinal damage
Autor:
Junji Yodoi, Aoi Son, Yumiko Nishinaka, Yasuyuki Ishii, Shingo Suzuki, Norihiko Kondo, Hiroshi Masutani, Shinae Kizaka-Kondoh, Junko Sakakura-Nishiyama, Yoshiyuki Matsuo, Masami Kojima, Yoshimi Yamaguchi
Publikováno v:
Archives of Biochemistry and Biophysics. 423:81-87
Various proteins sharing thioredoxin (Trx)-like active site sequences (Cys-Xxx-Xxx-Cys) have been found and classified in the Trx superfamily. Among them, transmembrane Trx-related protein (TMX) was recently identified as a novel protein possessing a
Autor:
Toshinori Nakayama, Junji Yodoi, Yasuyuki Ishii, Junko Sakakura-Nishiyama, Yong-Won Kwon, Yumiko Nishinaka, Norihiko Kondo, Aoi Son, Masaki Tanito, Masaru Taniguchi, Yoshiyuki Matsuo
Publikováno v:
Immunology Letters. 92:143-147
Thioredoxin (TRX) superfamily proteins that contain a conserved redox-active site -Cys-Xa.a.-Xa.a.-Cys- includes proinflammatory cytokine, macrophage migration inhibiting factor (MIF) and the immune regulatory cytokine, glycosylation inhibiting facto