Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Norihide Jo"'
Autor:
Norihide Jo, Rui Zhang, Hideki Ueno, Takuya Yamamoto, Daniela Weiskopf, Miki Nagao, Shinya Yamanaka, Yoko Hamazaki
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Age is a major risk factor for COVID-19 severity, and T cells play a central role in anti-SARS-CoV-2 immunity. Because SARS-CoV-2-cross-reactive T cells have been detected in unexposed individuals, we investigated the age-related differences in pre-e
Externí odkaz:
https://doaj.org/article/0972f62376b243a7af034d4589a3463d
Autor:
Shingo Komura, Kenji Ito, Sho Ohta, Tomoyo Ukai, Mio Kabata, Fumiaki Itakura, Katsunori Semi, Yutaka Matsuda, Kyoichi Hashimoto, Hirofumi Shibata, Masamitsu Sone, Norihide Jo, Kazuya Sekiguchi, Takatoshi Ohno, Haruhiko Akiyama, Katsuji Shimizu, Knut Woltjen, Manabu Ozawa, Junya Toguchida, Takuya Yamamoto, Yasuhiro Yamada
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
The EWS-ATF1 fusion gene causes clear cell sarcoma (CCS). Here, the authors show that the downstream effects of EWS-ATF1 expression are strictly context dependent, and reveal the cell of origin for CCS to be Tppp3-expressing cells in peripheral nerve
Externí odkaz:
https://doaj.org/article/d6a0a59accc9488fa4d118ffc7d1f1f9
Autor:
Yukinori Terada, Norihide Jo, Yoshiki Arakawa, Megumi Sakakura, Yosuke Yamada, Tomoyo Ukai, Mio Kabata, Kanae Mitsunaga, Yohei Mineharu, Sho Ohta, Masato Nakagawa, Susumu Miyamoto, Takuya Yamamoto, Yasuhiro Yamada
Publikováno v:
Cell Reports, Vol 26, Iss 10, Pp 2608-2621.e6 (2019)
Summary: Atypical teratoid/rhabdoid tumor (AT/RT), which harbors SMARCB1 mutation and exhibits a characteristic histology of rhabdoid cells, has a poor prognosis because of the lack of effective treatments. Here, we establish human SMARCB1-deficient
Externí odkaz:
https://doaj.org/article/a21290f37a8448f6882ad39ced9eab91
Autor:
Norihide Jo, Yu Hidaka, Osamu Kikuchi, Masaru Fukahori, Takeshi Sawada, Masahiko Aoki, Masaki Yamamoto, Miki Nagao, Satoshi Morita, Takako E. Nakajima, Manabu Muto, Yoko Hamazaki
Publikováno v:
Nature Aging. 3(1):82-92
Whether age-associated defects in T cells impact the immunogenicity and reactogenicity of mRNA vaccines remains unclear. Using a vaccinated cohort (n = 216), we demonstrated that older adults (aged ≥65 years) had fewer vaccine-induced spike-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2212f678d4f989434ea5d538cc36d4e
http://hdl.handle.net/2433/278730
http://hdl.handle.net/2433/278730
Autor:
Norihide Jo, Yu Hidaka, Osamu Kikuchi, Masaru Fukahori, Takeshi Sawada, Masahiko Aoki, Masaki Yamamoto, Miki Nagao, Satoshi Morita, Takako E. Nakajima, Manabu Muto, Yoko Hamazaki
Publikováno v:
Nature Aging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b907547d8db9d1dc9ed93db758658c3
https://doi.org/10.1038/s43587-023-00426-w
https://doi.org/10.1038/s43587-023-00426-w
Autor:
Norihide Jo, Yu Hidaka, Osamu Kikuchi, Masaru Fukahori, Takeshi Sawada, Masahiko Aoki, Masaki Yamamoto, Miki Nagao, Satoshi Morita, Takako E Nakajima, Manabu Muto, Yoko Hamazaki
Despite the clinical efficacy of coronavirus disease 2019 mRNA vaccines, the elderly demonstrate lower IgG levels and neutralizing titers and a higher risk of severe diseases. CD4+ T cells play a central role in regulating antigen-specific antibody a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32410f043cafc434dd4ae06a9f1beaba
https://doi.org/10.1101/2022.05.10.490700
https://doi.org/10.1101/2022.05.10.490700
Autor:
Manabu Ozawa, Takuya Yamamoto, Kenji Ito, Masamitsu Sone, Tomoyo Ukai, Junya Toguchida, Kazuya Sekiguchi, Takatoshi Ohno, Katsuji Shimizu, Shingo Komura, Mio Kabata, Fumiaki Itakura, Katsunori Semi, Kyoichi Hashimoto, Knut Woltjen, Sho Ohta, Y. Matsuda, Hirofumi Shibata, Yasuhiro Yamada, Haruhiko Akiyama, Norihide Jo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Nature Communications
Nature Communications
Clear cell sarcoma (CCS) is a rare soft tissue sarcoma caused by the EWS/ATF1 fusion gene. Here, we established induced pluripotent stem cells (iPSCs) from EWS/ATF1-controllable murine CCS cells harboring sarcoma-associated genetic abnormalities. Sar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bf6683d97cabdcabf62b15b87821a6
https://doaj.org/article/d6a0a59accc9488fa4d118ffc7d1f1f9
https://doaj.org/article/d6a0a59accc9488fa4d118ffc7d1f1f9
Autor:
Yuko Sogabe, Kanae Mitsunaga, Yasuhiro Yamada, Knut Woltjen, Harunobu Kagawa, Tomoyo Ukai, Norihide Jo
Publikováno v:
Cancer Science
The emergence of clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 technology has dramatically advanced how we manipulate the genome. Regarding in vivo experiments, Cas9-transgenic animals could provide efficient and complex geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dead69cff01ac2781578b2cc1e546e3
http://europepmc.org/articles/PMC6398895
http://europepmc.org/articles/PMC6398895
Autor:
Norihide Jo, Yohei Mineharu, Susumu Miyamoto, Yasuhiro Yamada, Yoshiki Arakawa, Yukinori Terada
Publikováno v:
Neuro-oncology Advances
Atypical teratoid/rhabdoid tumor (AT/RT), which harbors SMARCB1 mutation and exhibits a characteristic histology of rhabdoid cells, has a poor prognosis because of the lack of effective treatments. We established human SMARCB1-deficient pluripotent s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323c4b44a44ed67814040c3e06518d65
http://europepmc.org/articles/PMC7213114
http://europepmc.org/articles/PMC7213114
Akademický článek
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