Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Noriaki Nagai"'
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Background Brinzolamide (BRI) suspensions are used for the treatment of glaucoma; however, sufficient drug delivery to the target tissue after eye drop administration is hampered by poor solubility. To address this issue, we focused on nanoc
Externí odkaz:
https://doaj.org/article/aa4d1cdaaa32438996c2b3a5cfeaa1b5
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Neokestose is considered to have a prebiotic function. However, the physiological activity of neokestose remains unknown. Neokestose has a blastose, a sucrose analog, in its structure. We previously demonstrated that oral administration of b
Externí odkaz:
https://doaj.org/article/d0f4679e38024b95988a545933cc5491
Autor:
Tomohiro Yoshikawa, Hiroyo Okamoto, Kenta Takeuchi, Atsushi Hirata, Hiroko Otake, Noriaki Nagai
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Background The improvement in flowability and adhesion of starch powder (SP) is essential for using starch as an excipient for lactose intolerant patients. In this study, we attempted to evaluate the usefulness of hydroxypropylcellulose with
Externí odkaz:
https://doaj.org/article/d1d86c462c6248faa02c034a701953c2
Autor:
Saori Deguchi, Ayusa Iwakami, Mizuki Tujigiwa, Hiroko Otake, Yu Mano, Naoki Yamamoto, Yosuke Nakazawa, Manju Misra, Noriaki Nagai
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Background Gastrointestinal injuries caused by nonsteroidal anti-inflammatory drugs (NSAIDs) is a serious side effect in patients with rheumatoid arthritis (RA). However, effective therapeutic strategies have yet to be established. In this s
Externí odkaz:
https://doaj.org/article/5986d1cbd97442e0a2b83149ea69207f
Autor:
Reita Kadowaki, Fumihiko Ogata, Aoi Fushiki, Saki Daimyo, Saori Deguchi, Hiroko Otake, Mayumi Nagata, Hiroshi Sasaki, Naohito Kawasaki, Noriaki Nagai
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Background It is important to design an effective formulation to enhance the skin penetration, and nanotechnologies have been used in dermal and transdermal drug delivery. In this study, we prepared formulations (gels) containing l-menthol a
Externí odkaz:
https://doaj.org/article/6fc1f39109f84836ab0dab1c159f62bd
Autor:
Fumihiko Ogata, Noriaki Nagai, Chihiro Ito, Yuhei Kobayashi, Mizuki Yamaguchi, Ayako Tabuchi, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki
Publikováno v:
Water Science and Technology, Vol 85, Iss 10, Pp 2827-2839 (2022)
To increase the adsorption capability of Hg2+ from aqueous media, we prepared sodium-type fine zeolite grains with various particle sizes (denoted as ZE1, ZE2 and ZE3). The particle sizes of ZE1, ZE2 and ZE3 were 16.363 ± 0.365, 1.454 ± 0.357 and 0
Externí odkaz:
https://doaj.org/article/431d79918ba3437c912445b1cf8a8779
Autor:
Fumihiko Ogata, Yugo Uematsu, Noriaki Nagai, Ibuki Kobata, Ayako Tabuchi, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e14503- (2023)
In this study, waste biomass adsorbents produced from mangosteen shells (MGS) were prepared (denoted as MGS500 and MGS1000). The physical and chemical characteristics, such as scanning electron microscopy, thermogravimetric-differential thermal analy
Externí odkaz:
https://doaj.org/article/0d1c18ab35534e3992eb53e588fbf4dc
Autor:
Noriaki Nagai, Fumihiko Ogata, Reita Kadowaki, Saori Deguchi, Hiroko Otake, Yosuke Nakazawa, Mayumi Nagata, Hiroshi Sasaki, Naohito Kawasaki
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
The permeability of the Biopharmaceutics Classification System (BCS) class III drugs are low, and their oral bioavailability needs to be improved. In this study, we attempted to design oral formulations containing famotidine (FAM) nanoparticles to ov
Externí odkaz:
https://doaj.org/article/cb709341ff1a4f01819484f812b4fd1e
Autor:
Yuya Otaka, Kazutaka Kanai, Daiki Okada, Noriaki Nagai, Yohei Yamashita, Yoichiro Ichikawa, Kazuki Tajima
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13525 (2023)
The metabolism of 5-aminolevulinic acid (ALA) is more efficient when combined with sodium ferrous citrate (SFC). Our previous study revealed that oral administration of ALA, which has anti-inflammatory properties, and SFC (ALA/SFC) immediately before
Externí odkaz:
https://doaj.org/article/3a8873c432cd4060bb78f3373d3e2341
Autor:
Mayu Kawaguchi, Kana Matsumoto, Joji Yoshitomi, Hiroko Otake, Kanta Sato, Atsushi Taga, Tatsuji Sasabe, Kenji Nobuhara, Akira Matsubara, Noriaki Nagai
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292447 (2023)
N,N-diethyl-meta-toluamide (DEET) is a widely used insect repellent, with minimal skin permeation and sustained repellent activity in the superficial layers of the skin. In this study, we prepared a 10% DEET formulation consisting of 40% ethanol with
Externí odkaz:
https://doaj.org/article/67d811be5e144a46b8fa507177bb4cf7