Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Noriaki Manaka"'
Autor:
Toshiko Yamazawa, Takuya Kobayashi, Nagomi Kurebayashi, Masato Konishi, Satoru Noguchi, Takayoshi Inoue, Yukiko U. Inoue, Ichizo Nishino, Shuichi Mori, Hiroto Iinuma, Noriaki Manaka, Hiroyuki Kagechika, Arkady Uryash, Jose Adams, Jose R. Lopez, Xiaochen Liu, Christine Diggle, Paul D. Allen, Sho Kakizawa, Keigo Ikeda, Bangzhong Lin, Yui Ikemi, Kazuto Nunomura, Shinsaku Nakagawa, Takashi Sakurai, Takashi Murayama
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Mutations in ryanodine receptor 1 (RyR1), a Ca2+ release channel in skeletal muscle, cause malignant hyperthermia (MH) and are involved in heat stroke. Here, the authors show that an oxolinic acid-derivative RyR1 inhibitor effectively prevents and tr
Externí odkaz:
https://doaj.org/article/afd2999f767e49b494c83b5f5e5c1a4b
Autor:
Kazuto Nunomura, Shinsaku Nakagawa, Christine P. Diggle, Xiaochen Liu, Masato Konishi, Bangzhong Lin, Jose R. Lopez, Takashi Sakurai, Keigo Ikeda, Paul D. Allen, Nagomi Kurebayashi, Toshiko Yamazawa, Jose A. Adams, Takuya Kobayashi, Arkady Uryash, Ichizo Nishino, Takayoshi Inoue, Satoru Noguchi, Hiroyuki Kagechika, Hiroto Iinuma, Yui Ikemi, Yukiko U. Inoue, Noriaki Manaka, Takashi Murayama, Shuichi Mori, Sho Kakizawa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
Mutations in the type 1 ryanodine receptor (RyR1), a Ca2+ release channel in skeletal muscle, hyperactivate the channel to cause malignant hyperthermia (MH) and are implicated in severe heat stroke. Dantrolene, the only approved drug for MH, has the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0784e7e4d92a27a0b6fb10129773a22b
https://doaj.org/article/afd2999f767e49b494c83b5f5e5c1a4b
https://doaj.org/article/afd2999f767e49b494c83b5f5e5c1a4b
Autor:
Takashi Sakurai, Nagomi Kurebayashi, Takashi Murayama, Noriaki Manaka, Hiroto Iinuma, Ryota Arai, Yoshiaki Nishijima, Shuichi Mori, Akiko Sakurai, Hiroyuki Kagechika, Mari Ishigami-Yuasa
Publikováno v:
European Journal of Medicinal Chemistry. 179:837-848
Type-1 ryanodine receptor (RyR1) is a calcium-release channel localized on sarcoplasmic reticulum (SR) of the skeletal muscle, and mediates muscle contraction by releasing Ca2+ from the SR. Genetic mutations of RyR1 are associated with skeletal muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74ac93f3de29fe29727adec18d293522
https://doi.org/10.1016/j.ejmech.2019.06.076
https://doi.org/10.1016/j.ejmech.2019.06.076
Autor:
Jose R. Lopez, Takuya Kobayashi, Shinsaku Nakagawa, Satoru Noguchi, Hiroto Iinuma, Paul D. Allen, Takashi Murayama, Shuichi Mori, Ichizo Nishino, Takayoshi Inoue, Yui Ikemi, Arkady Uryas, Christine P. Diggle, Jose A. Adams, Bangzhong Lin, Keigo Ikeda, Yukiko U. Inoue, Nagomi Kurebayashi, Masato Konishi, Noriaki Manaka, Toshiko Yamazawa, Takashi Sakurai, Sho Kakizawa, Xiaochen Liu, Kazuto Nunomura, Hiroyuki Kagechika
Mutations in the type 1 ryanodine receptor (RyR1), a Ca2+ release channel in skeletal muscle, hyperactivate the channel to cause malignant hyperthermia (MH) and are implicated in severe heat stroke. Dantrolene, the only approved drug for MH, has the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c138a68bf6f1a59066ecf996fdfbda23
https://doi.org/10.1101/2020.07.02.185520
https://doi.org/10.1101/2020.07.02.185520
Autor:
Shuichi, Mori, Hiroto, Iinuma, Noriaki, Manaka, Mari, Ishigami-Yuasa, Takashi, Murayama, Yoshiaki, Nishijima, Akiko, Sakurai, Ryota, Arai, Nagomi, Kurebayashi, Takashi, Sakurai, Hiroyuki, Kagechika
Publikováno v:
European journal of medicinal chemistry. 179
Type-1 ryanodine receptor (RyR1) is a calcium-release channel localized on sarcoplasmic reticulum (SR) of the skeletal muscle, and mediates muscle contraction by releasing Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e048e0aa295ba20c36a78a70d167e8a
https://pubmed.ncbi.nlm.nih.gov/31299492
https://pubmed.ncbi.nlm.nih.gov/31299492
Autor:
Takashi Murayama, Hiroto Iinuma, Hiroyuki Kagechika, Mari Ishigami-Yuasa, Shuichi Mori, Noriaki Manaka, Yoshiaki Nishijima, Nagomi Kurebayashi, Takashi Sakurai
Publikováno v:
Biophysical Journal. 116:521a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49104e9c82a49b51935f70aeb577d8bd
https://doi.org/10.1016/j.bpj.2018.11.2811
https://doi.org/10.1016/j.bpj.2018.11.2811
Autor:
Noriaki Manaka, Shuichi Mori, Yoshiaki Nishijima, Hiroto Iinuma, Takashi Sakurai, Nagomi Kurebayashi, Takashi Murayama, Hiroyuki Kagechika, Mari Ishigami-Yuasa
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:2-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::928eff53c886b9efcf1f5c0c8f5e22cc
https://doi.org/10.1254/jpssuppl.92.0_2-o-25
https://doi.org/10.1254/jpssuppl.92.0_2-o-25