Výsledky vyhledávání - "Noriaki Ishigami"

Intratubular Spermatocytic Seminomas in 2 Sprague-Dawley Rats

Publikováno v: Journal of Toxicologic Pathology

This report describes 2 cases of spontaneous intratubular spermatocytic seminomas in Sprague-Dawley rats. These rats were sacrificed at 10 weeks old (case 1) and 40 weeks old (case 2), respectively. Macroscopically, there were no remarkable changes i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5d5e7d746966b46c96d6d25bd6f6f7
https://doi.org/10.1293/tox.2014-0005

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T-2 Toxin-induced Toxicity in Pregnant Mice and Rats

Autor: Noriaki Ishigami, Kunio Doi, Shinya Sehata

Publikováno v: International Journal of Molecular Sciences, Vol 9, Iss 11, Pp 2146-2158 (2008)
International Journal of Molecular Sciences

T-2 toxin is a cytotoxic secondary fungal metabolite that belongs to the trichothecene mycotoxin family. This mycotoxin is a well known inhibitor of protein synthesis through its high binding affinity to peptidyl transferase, which is an integral par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d874ac6645ade8d89b15574caa19872b
http://www.mdpi.com/1422-0067/9/11/2146/

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Nivalenol-induced apoptosis in thymus, spleen and Peyer's patches of mice

Autor: Ryoichi Ohtsuka, Kunio Doi, Hiroyuki Nakayama, Wijit Kiatipattanasakul, Amnart Poapolathep, Noriaki Ishigami

Publikováno v: Experimental and Toxicologic Pathology. 53:441-446

ICR:CD-1 male mice were orally administered with Nivalenol(NIV) at the dose levels of 5, 10 and 15 mg/kg body weight, and examined at 12, 24 and 48 hours after inoculation (HAI), respectively, to elucidate the process of development of apoptosis in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178124478d0593834caf4af011fb6c1c
https://doi.org/10.1078/0940-2993-00211

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Development of apoptosis and changes in lymphocyte subsetsin thymus, mesenteric lymph nodes and Peyer's patches of mice orally inoculated with T-2 toxin

Autor: K. Uetsuka, Junko Shinozuka, Hodaka Suzuki, Hiroyuki Nakayama, Takayuki Nagata, Noriaki Ishigami, Kunio Doi

Publikováno v: Experimental and Toxicologic Pathology. 53:309-315

Development of apoptosis and changes in lymphocyte subsets were examined mainly by flow cytometer in thymus, mesenteric lymph nodes and Peyer's patches of mice up to 24 hours after oral inoculation with T-2 toxin (10 mg/kg). T-2 toxin attacked Peyer'

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e1d17acce10e98db8d0873cc9a657a
https://doi.org/10.1078/0940-2993-00196

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Development of Apoptosis and Changes in Apoptosis-related Genes Expression in the Mouse Thymus Following T-2 Toxin-inoculation

Autor: Hiroyuki Nakayama, Shigeki Tsutsui, Junko Shinozuka, Noriaki Ishigami, Kunio Doi, Aito Ueno-Yamanouchi

Publikováno v: Journal of Toxicologic Pathology. 12:77-81

T-2 toxin is a kind of trichothecene mycotoxin produced by species of the genus Fusarium, and it attacks the tissues containing a large number of actively dividing cells such as lymphoid and hematopoietic tissues. The development of apoptosis and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a8ef763058c52c40ed242a5493b800c
https://doi.org/10.1293/tox.12.77

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Survey of Nematodes of Tokara Ponies in Nakanoshima Island of Kagoshima

Autor: Noriaki Ishigami, Nobuhiro Yasuda, Tsutomu Shimizu, Noriaki Miyoshi

Publikováno v: Journal of the Japan Veterinary Medical Association. 51:303-306

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::445f3e313ebae3d3fc06862547915e48
https://doi.org/10.12935/jvma1951.51.303

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Apoptosis in mouse fetuses from dams exposed to T-2 toxin at different days of gestation

Autor: Kunio Doi, Noriaki Ishigami, Kei-ichi Katayama, Junko Shinozuka, Hiroyuki Nakayama

Publikováno v: ResearcherID

T-2 toxin (2 mg/kg b.w.) was orally inoculated to pregnant mice at gestational day (GD) 8.5, 9.5, 10.5, 11.5, 12.5, 13.5, 14.5, 15.5 and GD 16.5, respectively, and the fetuses were examined 24 hours later. The number and region of pyknotic or karyorr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c463675bf58d2c366d940dec45b2c1
https://pubmed.ncbi.nlm.nih.gov/11256751

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Teratologic studies on rat perinates and offspring from dams treated with ethylnitrosourea (ENU)

Autor: Kunio Doi, Noriaki Ishigami, Wijit Kiatipattanasakul, Michio Suzuki, Ryoichi Ohtsuka, Kei-ichi Katayama, Hiroyuki Nakayama

Publikováno v: Experimental animals. 49(3)

Ethylnitrosourea (ENU), a well known DNA alkylating agent, induces anomalies in the central nervous system (CNS), craniofacial tissues, limbs and male reproductive organs. Recently we clarified that excess cell death caused by apoptosis occurred in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b787f146523d83063387b5ad60f5575
https://pubmed.ncbi.nlm.nih.gov/11109540

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