Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Noriaki Hirayama"'
Autor:
Nobuo Watanabe, Masako Kidokoro, Makiko Tanaka, Shigeaki Inoue, Tomoatsu Tsuji, Hisako Akatuska, Chisa Okada, Yumi Iida, Yoshinori Okada, Yusuke Suzuki, Takehito Sato, Takashi Yahata, Noriaki Hirayama, Yoshihide Nakagawa, Sadaki Inokuchi
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-22 (2020)
Abstract Background The transmembrane glycoprotein podoplanin (PDPN) is upregulated in some tumors and has gained attention as a malignant tumor biomarker. PDPN molecules have platelet aggregation-stimulating domains and, are therefore, suggested to
Externí odkaz:
https://doaj.org/article/5a1af4a7f9584ec687fe39ffbfbe6e70
Autor:
Shino Ohshima, Tatsuya Matsubara, Asuka Miyamoto, Atsuko Shigenari, Noriaki Imaeda, Masaki Takasu, Masafumi Tanaka, Takashi Shiina, Shingo Suzuki, Noriaki Hirayama, Hitoshi Kitagawa, Jerzy K Kulski, Asako Ando, Yoshie Kametani
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242572 (2020)
Cluster of differentiation 4 (CD4) molecule expressed on the leukocytes is known to function as a co-receptor for class II major histocompatibility complex (MHC) binding to T cell receptor (TCR) on helper T cells. We previously identified two CD4 all
Externí odkaz:
https://doaj.org/article/c8f5c1550d2b4976b5cfe68fc2ed239d
Autor:
Nobuo Watanabe, Yusuke Suzuki, Takahisa Yonezu, Yuki Nakagawa, Takashi Shiina, Noriaki Hirayama, Sadaki Inokuchi, Shigeaki Inoue
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract A number of autoimmune diseases are associated with the genotypes of human leukocyte antigen class II (HLA), some of which present peptides derived from self-proteins, resulting in clonal expansion of self-reactive T cells. Therefore, select
Externí odkaz:
https://doaj.org/article/a45b10110a54476c84daacb6b46f2609
Autor:
Nobuo Watanabe, Masako Kidokoro, Yusuke Suzuki, Makiko Tanaka, Shigeaki Inoue, Hideo Tsukamoto, Noriaki Hirayama, Pei-Wen Hsieh, Ching-Ping Tseng, Yoshihide Nakagawa, Sadaki Inokuchi
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222331 (2019)
Podoplanin, a transmembrane glycoprotein, is overexpressed in certain types of tumors and induces platelet aggregation by binding to C-type lectin-like receptor 2 (CLEC-2) on the platelet membrane. Activated platelets release granule components, whic
Externí odkaz:
https://doaj.org/article/c54fab57e9d14e70b7d85211ec6bb248
Autor:
Yoshie Kametani, Shino Ohshima, Asuka Miyamoto, Atsuko Shigenari, Masaki Takasu, Noriaki Imaeda, Tatsuya Matsubara, Masafumi Tanaka, Takashi Shiina, Hiroshi Kamiguchi, Ryuji Suzuki, Hitoshi Kitagawa, Jerzy K Kulski, Noriaki Hirayama, Hidetoshi Inoko, Asako Ando
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164995 (2016)
The class I major histocompatibility complex (MHC) presents self-developed peptides to specific T cells to induce cytotoxity against infection. The MHC proteins are encoded by multiple loci that express numerous alleles to preserve the variability of
Externí odkaz:
https://doaj.org/article/c3d9f5e8430f42769ac221ee8cf572e1
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1660 (2018)
Human leukocyte antigen (HLA)-DRB1*01:01 has been shown to be involved in nevirapine-induced hepatic hypersensitivity reactions. In the present study, in silico docking simulations and molecular dynamics simulations were performed to predict the inte
Externí odkaz:
https://doaj.org/article/358a9976b14a4b1797e599d48a0caa10
Autor:
Kazunori Tanaka, Takuya Kanno, Yoshiko Yanagisawa, Kaori Yasutake, Satoshi Inoue, Noriaki Hirayama, Joh-E Ikeda
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87728 (2014)
Amyotrophic lateral sclerosis (ALS) is an adult-onset motor neuron degenerative disease. Given that oxidative stress and resulting chronic neuronal inflammation are thought to be central pathogenic, anti-oxidative agents and modulators of neuronal in
Externí odkaz:
https://doaj.org/article/42da0d67f6444d5f9c1db3e0aa957082
Autor:
Hideto Isogai, Hiroko Miyadera, Mayumi Ueta, Chie Sotozono, Shigeru Kinoshita, Katsushi Tokunaga, Noriaki Hirayama
Publikováno v:
Journal of Toxicology, Vol 2013 (2013)
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe drug hypersensitivities with high mortality. Typical over-the-counter drugs of cold medicines are suggested to be causative. As multiple ingredients are generally containe
Externí odkaz:
https://doaj.org/article/5305ffaed1cd4958b5b5ad61596d9b54
Publikováno v:
Chem-Bio Informatics Journal. 20:1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfc6419373a5d785909ef18c259fa0f7
https://doi.org/10.1273/cbij.20.1
https://doi.org/10.1273/cbij.20.1
Autor:
Toshiro Seki, Kou Sakabe, Erika Sasaki, Mikio Mikami, Rihito Kinami, Hitoshi Ishimoto, Kazumi Takahashi, Noriaki Hirayama, Asako Otomo, Yoshie Kametani, Takashi Shiina, Sun-ichiro Izumi, Hirofumi Kashiwagi, Fuyuki Kametani
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
While pregnancy-related proteins (PRP) are known to contribute to immunotolerance during pregnancy, their significance to development of invasive placenta is unclear. We compared PRP expression in humans and the common marmoset (Callithrix jacchus),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbc42d2db2bc84b5670b719dfe92271
http://link.springer.com/article/10.1038/s41598-020-61714-8
http://link.springer.com/article/10.1038/s41598-020-61714-8