Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Noriaki, Takabatake"'
Publikováno v:
International Journal of Biological Sciences, Vol 5, Iss 4, Pp 304-310 (2009)
We investigated the potential usefulness of vesnarinone, a novel cytokine inhibitor, for the treatment of lung fibrosis using a murine model of bleomycin (BLM)-induced pulmonary fibrosis. Mice were fed a control diet (n=42), or a diet containing low
Externí odkaz:
https://doaj.org/article/723f05925933449e92aa6061352e311f
Autor:
Takeo Kato, Daisuke Osaka, Isao Kubota, Keiko Yamauchi, Sumio Kawata, Yoko Shibata, Hiroyuki Kishi, Akira Igarashi, Yoshikane Tokairin, Tomomi Kimura, Noriaki Takabatake, Shuichi Abe, Michiko Sato, Makoto Sata, Tsuneo Konta, Tetsu Watanabe, Sumito Inoue
Publikováno v:
Internal Medicine. 49:1489-1499
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation. The prevalence of airflow limitation in Japan is 10.9% (16.4% of males and 5.0% of females). Cigarette smoking is well known as a major cause of C
Autor:
Mitsuru Emi, Takeo Kato, Isao Kubota, Sumio Kawata, Yoko Shibata, Sayumi Toriyama, Kazunobu Ichikawa, Yasuchika Takeishi, Tsuneo Konta, Ami Ikeda, Satoshi Takasaki, Noriaki Takabatake
Publikováno v:
Kidney International. 76(2):183-189
Paraoxonase-1 (PON1) is an HDL cholesterol-associated antioxidant enzyme, and some of its polymorphisms are linked with systemic oxidative stress and cardiovascular events. In this study, we genotyped seven single nucleotide polymorphisms (SNPs) with
Autor:
Hitonobu Tomoike, Kyoko Terashita, Tetsumi Hosokawa, Shuichi Kato, Noriaki Takabatake, Shuichi Abe, Hiroshi Saito, Minoru Inage, Makoto Sata, Manabu Ogura, Toshihiko Hino, Hidenori Nakamura
Publikováno v:
International Journal of Biological Sciences
We investigated the potential usefulness of vesnarinone, a novel cytokine inhibitor, for the treatment of lung fibrosis using a murine model of bleomycin (BLM)-induced pulmonary fibrosis. Mice were fed a control diet (n=42), or a diet containing low
Autor:
Shuichi Abe, Makoto Sata, Noriaki Takabatake, Isao Kubota, Tomomi Ishikawa, Akira Igarashi, Sumito Inoue, Yoshikane Tokairin, Yoko Shibata
Publikováno v:
Respirology. 13:324-332
Background and objective: Pulmonary emphysema is associated with frequent respiratory infections but little is known about the reasons for this susceptibility to bacterial infection. We previously demonstrated an impaired inflammatory response to Str
Autor:
Noriaki Takabatake, Takeo Kato, Sumio Kawata, Yoko Shibata, Sumito Inoue, Yasuchika Takeishi, Tsuneo Konta, Isao Kubota, Akira Igarashi, Sayumi Toriyama, Satoru Koyano, Yoshikane Tokairin, Mitsuru Emi, Miho Ishii, Shuichi Abe
Publikováno v:
Biochemical and Biophysical Research Communications. 364:662-667
The forced expiratory volume in the first second (FEV1.0)/the forced vital capacity (FVC) is an important index of a single forced expiration. Ectopic expression of the human olfactory receptor (OR) gene family in the lungs has suggested its potentia
Autor:
Makoto Sata, Yoko Shibata, Noriyuki Hirama, Jun-ichi Machiya, Isao Kubota, Noriaki Takabatake, Sumito Inoue, Toshihiro Wada, Kazuhisa Otake, Shuichi Abe
Publikováno v:
Respirology. 12:191-201
Background and objective: The molecular mechanisms underlying COPD remain undetermined. The lungs of surfactant protein-D (SP-D) deficient mice show emphysema and an excessive number of foamy macrophages. This study aims to elucidate roles of SP-D an
Autor:
Takanori Arimoto, Isao Kubota, Joji Nitobe, Noriaki Takabatake, Osamu Hirono, Tetsu Watanabe, Mutsuo Harada, Takeshi Niizeki, Yasuchika Takeishi, Naoki Nozaki, Toshiki Sasaki, Satoshi Suzuki, Tatsuro Kitahara, Yo Koyama
Publikováno v:
Journal of Cardiac Failure. 13:120-127
Heart-type fatty acid-binding protein (H-FABP) is a small cytosolic protein and released into the circulation when the myocardium is injured. Previous studies have demonstrated that both H-FABP and troponin T (TnT) are detectable in venous blood samp
Autor:
Isao Kubota, Sumio Kawata, Yoko Shibata, Yasuchika Takeishi, Noriaki Takabatake, Takeo Kato, Takeshi Niizeki, Tsuneo Konta
Publikováno v:
Circulation Journal. 71:1452-1457
Background Serum heart-type fatty acid-binding protein (H-FABP) has been widely used as a marker of cardiac myocyte injury. This study was carried out to examine the relationships of H-FABP levels with age, gender, and other physiologic characteristi
Autor:
Noriaki Takabatake, Makoto Sata, Yoko Shibata, Masaaki Muramatsu, Guijin Ji, Yasuchika Takeishi, Tadashi Matsuura, Isao Kubota, Sumito Inoue, Toshihiro Wada, Jun-ichi Machiya, Shuichi Abe
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 172:1097-1104
Rationale: Chronic and systemic inflammation, a potential cause of body weight loss in patients with chronic obstructive pulmonary disease (COPD), may be associated with the proinflammatory properties of secretory phospholipases A2 (sPLA2s), especial