Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Noriaki, SHIMIZU"'
Autor:
Hitomi Sano, Anton Kratz, Taiko Nishino, Haruna Imamura, Yuki Yoshida, Noriaki Shimizu, Hiroaki Kitano, Ayako Yachie
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract NMN is the direct precursor of nicotinamide adenine dinucleotide (NAD+) and is considered as a key factor for increasing NAD+ levels and mitochondrial activity in cells. In this study, based on transcriptome analysis, we showed that NMN alle
Externí odkaz:
https://doaj.org/article/6fa33bd49b824604b7b1b6419684a969
Autor:
Noriaki Shimizu, Rita Kapoor, Shuhei Naniwa, Naoto Sakamaru, Taku Yamada, You-ki Yamamura, Koh-ichi Utani
Publikováno v:
BMC Molecular and Cell Biology, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Extrachromosomal acentric double minutes (DMs) contribute to human malignancy by carrying amplified oncogenes. Recent cancer genomics revealed that the pulverization of defined chromosome arms (chromothripsis) may generate DMs, ho
Externí odkaz:
https://doaj.org/article/9302f9a1aa0d4276a3ac991fc087f145
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0235127 (2020)
Repeat-induced gene silencing (RIGS) establishes the centromere structure, prevents the spread of transposons and silences transgenes, thereby limiting recombinant protein production. We previously isolated a sequence (B-3-31) that alleviates RIGS fr
Externí odkaz:
https://doaj.org/article/4949739a4adc439e9371f9561d4c97ef
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Satellite cells comprise a functionally heterogeneous population of stem cells in skeletal muscle. Separation of an undifferentiated subpopulation and elucidation of its molecular background are necessary to identify the reprogramming factor
Externí odkaz:
https://doaj.org/article/2192f1b78b2b4c83b213bbecf54c7814
Autor:
Ryuji Hamamoto, Yusuke Nakamura, Yoshihiko Maehara, Bruce A.J. Ponder, David E. Neal, John D. Kelly, Helen I. Field, Tatsuhiko Tsunoda, Hirotoshi Tanaka, Noriaki Shimizu, Kazuhiro Maejima, Shinya Hayami, Masashi Takawa, Masanori Yoshimatsu, Yukiko Iwai, Hyun-Soo Cho, Gouji Toyokawa
PDF file - 491K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d21028f62c1decd6c3b0e3c194fe6e
https://doi.org/10.1158/1940-6207.22524053
https://doi.org/10.1158/1940-6207.22524053
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175585 (2017)
Plasmids with both a mammalian replication initiation region (IR) and a matrix attachment region (MAR) are spontaneously amplified in transfected cells, and generate extrachromosomal double minute (DM) or chromosomal homogeneously staining region (HS
Externí odkaz:
https://doaj.org/article/f5b10e6fa7c14c2c9f9d9da5efbea59e
Autor:
Kisa, Tanabe, Yuho, Najima, Takuhiko, Inokuchi, Mae, Endo, Yuko, Nishio, Daichi, Sadato, Yasuhiro, Kanbara, Yuya, Atsuta, Ryosuke, Konuma, Hiroto, Adachi, Atsushi, Wada, Yuya, Kishida, Yusuke, Uchibori, Yuma, Noguchi, Junichi, Mukae, Naoki, Shingai, Takashi, Toya, Noriaki, Shimizu, Takeshi, Kobayashi, Hironori, Harada, Hisashi, Sakamaki, Kazuteru, Ohashi, Yuka, Harada, Tatsuro, Yamaguchi, Nobuya, Akizuki, Noriko, Doki
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 63(7)
A 22-year-old man with a history of mediastinal germ cell tumor, which was diagnosed at age 20 and remained disease-free after chemotherapy, was diagnosed with acute myeloid leukemia (AML) M2 in January 2020. Karyotype analysis of bone marrow (BM) sp
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153338 (2016)
Plasmids bearing a mammalian replication initiation region (IR) and a nuclear matrix attachment region (MAR) are spontaneously amplified in transfected mammalian cells, and such amplification generates chromosomal homogeneously staining regions (HSRs
Externí odkaz:
https://doaj.org/article/833e4b60bd074bdc8701136810670151
Autor:
Sho-Hei Mitsuda, Noriaki Shimizu
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161288 (2016)
A plasmid bearing both a replication initiation region and a matrix attachment region is spontaneously amplified in transfected mammalian cells and generates plasmid repeats in the extrachromosomal double minutes (DMs) or the chromosomal homogeneousl
Externí odkaz:
https://doaj.org/article/cc6d3a3154e24edfaa948adc6202548d
Autor:
Noriaki Shimizu
Publikováno v:
Genes, Vol 12, Iss 1533, p 1533 (2021)
Genes
Genes
Oncogene amplification is closely linked to the pathogenesis of a broad spectrum of human malignant tumors. The amplified genes localize either to the extrachromosomal circular DNA, which has been referred to as cytogenetically visible double minutes