Výsledky vyhledávání - "Nori Kurihara"

Juvenile Paget’s Disease From Heterozygous Mutation of SP7 Encoding Osterix (Specificity Protein 7, Transcription Factor Sp7)

Autor: Nori Kurihara, Homer Sedighi, Steven Mumm, Michael P. Whyte, William H. McAlister, Deborah J. Veis, G. David Roodman, Vinieth N. Bijanki, Philippe M. Campeau, Angela Nenninger, Gary S. Gottesman, Shenghui Duan

Publikováno v: Bone

Juvenile Paget's disease (JPD) became in 1974 the commonly used name for ultra-rare heritable occurrences of rapid bone remodeling throughout of the skeleton that present in infancy or early childhood as fractures and deformity hallmarked biochemical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a8f7629a04e8374c56b009d6052fe8
https://europepmc.org/articles/PMC8054448/

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SV40 T antigen and telomerase are required to obtain immortalized human adult bone cells without loss of the differentiated phenotype

Autor: Christian, Darimont, Ornella, Avanti, Yvonne, Tromvoukis, Patricia, Vautravers-Leone, Nori, Kurihara, G David, Roodman, Lorel M, Colgin, Heide, Tullberg-Reinert, Andrea M A, Pfeifer, Elizabeth A, Offord, Katherine, Mace

Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 13(2)

In most human primary bone cells, SV40 T-antigen expression was able to expand life span for a few passages before cells undergo growth arrest, described as crisis. In this study, telomerase activity was reconstituted in human osteoblast precursors (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d23256a52d19e49f311d9cee495fc18
https://pubmed.ncbi.nlm.nih.gov/11864909

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