Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Norhidayu Hasan"'
Autor:
Jia-Wern Pan, Zi-Ching Tan, Pei-Sze Ng, Muhammad Mamduh Ahmad Zabidi, Putri Nur Fatin, Jie-Ying Teo, Siti Norhidayu Hasan, Tania Islam, Li-Ying Teoh, Suniza Jamaris, Mee-Hoong See, Cheng-Har Yip, Pathmanathan Rajadurai, Lai-Meng Looi, Nur Aishah Mohd Taib, Oscar M. Rueda, Carlos Caldas, Suet-Feung Chin, Joanna Lim, Soo-Hwang Teo
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Triple-negative breast cancers (TNBCs) are a subset of breast cancers that have remained difficult to treat. A proportion of TNBCs arising in non-carriers of BRCA pathogenic variants have genomic features that are similar to BRCA carriers an
Externí odkaz:
https://doaj.org/article/d2857e682b734986b417f18c09ab31e4
Autor:
Jia-Wern Pan, Mohana Ragu, Wei-Qin Chan, Siti Norhidayu Hasan, Tania Islam, Li-Ying Teoh, Suniza Jamaris, Mee-Hoong See, Cheng-Har Yip, Pathmanathan Rajadurai, Lai-Meng Looi, Nur Aishah Mohd Taib, Oscar M. Rueda, Carlos Caldas, Suet-Feung Chin, Joanna Lim, Soo-Hwang Teo
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Breast cancer exhibits significant heterogeneity, manifesting in various subtypes that are critical in guiding treatment decisions. This study aimed to investigate the existence of distinct subtypes of breast cancer within the Asian populati
Externí odkaz:
https://doaj.org/article/351360a830af473c9b955d098b6ff1fa
Autor:
Jia-Wern Pan, Muhammad Mamduh Ahmad Zabidi, Pei-Sze Ng, Mei-Yee Meng, Siti Norhidayu Hasan, Bethan Sandey, Stephen-John Sammut, Cheng-Har Yip, Pathmanathan Rajadurai, Oscar M. Rueda, Carlos Caldas, Suet-Feung Chin, Soo-Hwang Teo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Molecular profiling of breast cancer in non-Caucasian populations remains underexplored. Here the authors report a high prevalence of HER2-subtypes and enriched immune score with improved survival and higher rates of TP53 somatic mutations with poore
Externí odkaz:
https://doaj.org/article/19a345c9f0be4ab783dcad50c106ed15
Autor:
Weang-Kee Ho, Min-Min Tan, Nasim Mavaddat, Mei-Chee Tai, Shivaani Mariapun, Jingmei Li, Peh-Joo Ho, Joe Dennis, Jonathan P. Tyrer, Manjeet K. Bolla, Kyriaki Michailidou, Qin Wang, Daehee Kang, Ji-Yeob Choi, Suniza Jamaris, Xiao-Ou Shu, Sook-Yee Yoon, Sue K. Park, Sung-Won Kim, Chen-Yang Shen, Jyh-Cherng Yu, Ern Yu Tan, Patrick Mun Yew Chan, Kenneth Muir, Artitaya Lophatananon, Anna H. Wu, Daniel O. Stram, Keitaro Matsuo, Hidemi Ito, Ching Wan Chan, Joanne Ngeow, Wei Sean Yong, Swee Ho Lim, Geok Hoon Lim, Ava Kwong, Tsun L. Chan, Su Ming Tan, Jaime Seah, Esther M. John, Allison W. Kurian, Woon-Puay Koh, Chiea Chuen Khor, Motoki Iwasaki, Taiki Yamaji, Kiak Mien Veronique Tan, Kiat Tee Benita Tan, John J. Spinelli, Kristan J. Aronson, Siti Norhidayu Hasan, Kartini Rahmat, Anushya Vijayananthan, Xueling Sim, Paul D. P. Pharoah, Wei Zheng, Alison M. Dunning, Jacques Simard, Rob Martinus van Dam, Cheng-Har Yip, Nur Aishah Mohd Taib, Mikael Hartman, Douglas F. Easton, Soo-Hwang Teo, Antonis C. Antoniou
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Polygenic risk scores predict the likelihood that an individual will develop a certain cancer, however these are often specific for a given population. Here, the authors show that a risk score developed to assess the risk of breast cancer in European
Externí odkaz:
https://doaj.org/article/c4e3ab2174674348a51d28c57a00ccd1
Autor:
Heamanthaa Padmanabhan, Nur Tiara Hassan, Siu-Wan Wong, Yong-Quan Lee, Joanna Lim, Siti Norhidayu Hasan, Cheng-Har Yip, Soo-Hwang Teo, Meow-Keong Thong, Nur Aishah Mohd Taib, Sook-Yee Yoon
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
There is an increasing number of cancer patients undertaking treatment-focused genetic testing despite not having a strong family history or high a priori risk of being carriers because of the decreasing cost of genetic testing and development of new
Externí odkaz:
https://doaj.org/article/d8962a9a727549f79753e8b8e971eb57
Predicting the Likelihood of Carrying a BRCA1 or BRCA2 Mutation in Asian Patients With Breast Cancer
Autor:
Boon Hong Ang, Weang Kee Ho, Eldarina Wijaya, Pui Yoke Kwan, Pei Sze Ng, Sook Yee Yoon, Siti Norhidayu Hasan, Joanna M.C. Lim, Tiara Hassan, Mei-Chee Tai, Jamie Allen, Andrew Lee, Nur Aishah Mohd Taib, Cheng Har Yip, Mikael Hartman, Swee Ho Lim, Ern Yu Tan, Benita K.T. Tan, Su-Ming Tan, Veronique K.M. Tan, Peh Joo Ho, Alexis J. Khng, Alison M. Dunning, Jingmei Li, Douglas F. Easton, Antonis C. Antoniou, Soo Hwang Teo
Publikováno v:
Journal of Clinical Oncology. 40:1542-1551
PURPOSE With the development of poly (ADP-ribose) polymerase inhibitors for treatment of patients with cancer with an altered BRCA1 or BRCA2 gene, there is an urgent need to ensure that there are appropriate strategies for identifying mutation carrie
Autor:
Min-Min Tan, Weang-Kee Ho, Sook-Yee Yoon, Shivaani Mariapun, Siti Norhidayu Hasan, Daphne Shin-Chi Lee, Tiara Hassan, Sheau-Yee Lee, Sze-Yee Phuah, Kavitta Sivanandan, Patsy Pei-Sze Ng, Nadia Rajaram, Maheswari Jaganathan, Suniza Jamaris, Tania Islam, Kartini Rahmat, Farhana Fadzli, Anushya Vijayananthan, Pathmanathan Rajadurai, Mee-Hong See, Meow-Keong Thong, Nur Aishah Mohd Taib, Cheng-Har Yip, Soo-Hwang Teo
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203469 (2018)
BackgroundBreast cancer risk factors have been examined extensively in Western setting and more developed Asian cities/countries. However, there are limited data on developing Asian countries. The purpose of this study was to examine breast cancer ri
Externí odkaz:
https://doaj.org/article/0d9fd67f42d24c44b94caba1f4d0e565
Autor:
Jia-Wern Pan, Pei-Sze Ng, Muhammad Mamduh Ahmad Zabidi, Putri Nur Fatin, Jie-Ying Teo, Siti Norhidayu Hasan, Cheng-Har Yip, Pathmanathan Rajadurai, Lai-Meng Looi, Aishah M. Taib, Oscar M. Rueda, Carlos Caldas, Suet-Feung Chin, Joanna Lim, Soo-Hwang Teo
Triple-negative breast cancers (TNBCs) are a subset of breast cancers that has remained difficult to treat. One of the more efficient treatments for TNBCs is by targeting the homologous recombination (HR) pathway, for example using PARP inhibitors, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b0f11f4e345b72f4ff824bc075001e0
https://doi.org/10.1101/2022.06.08.495296
https://doi.org/10.1101/2022.06.08.495296
Autor:
Pei-Sze Ng, Cheng Har Yip, Boon-Keat Chong, Carlos Caldas, Saira Bahnu, Siti Norhidayu Hasan, Soo Hwang Teo, Bethan Sandey, Oscar M. Rueda, Muhammad A. Zabidi, Mei-Yee Meng, Pathmanathan Rajadurai, Suet-Feung Chin, Jia-Wern Pan
Publikováno v:
International Journal of Cancer. 148:2489-2501
A 30-kb deletion that eliminates the coding region of APOBEC3B (A3B) is >5 times more common in women of Asian compared to European descent. This polymorphism creates a chimera with the APOBEC3A (A3A) coding region and A3B 3'UTR, and is associated wi
Publikováno v:
International Journal of Academic Research in Business and Social Sciences. 11