Zobrazeno 1 - 10
of 976
pro vyhledávání: '"Norepinephrine uptake"'
Autor:
Rui Xue, Xin-Hua He, Li Yuan, Hong-Xia Chen, Li-Ming Zhang, Zheng Yong, Gang Yu, Shi-Yong Fan, Yun-Feng Li, Bo-Hua Zhong, You-Zhi Zhang
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 1, Pp 1-7 (2016)
Our previous study indicated that 071031B, a novel potential serotonin and norepinephrine reuptake inhibitor, showed robust antidepressant activity in multiple depression models, and could simultaneously inhibit 5-HT and NE reuptake in vitro. The pre
Externí odkaz:
https://doaj.org/article/c8ab1876790c496d9cbf7ca0daafa5ec
Autor:
Wayne E. Childers, Magid Abou-Gharbia
Publikováno v:
ACS Med Chem Lett
[Image: see text] Beginning with opium itself, natural and synthetic opioids have been used as analgesics for over 8000 years and were likely abused as drugs of recreation for that long as well. However, the “opioid crisis” resulted in attempts t
Akademický článek
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Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1981 Jun 01. 78(6), 3959-3963.
Externí odkaz:
https://www.jstor.org/stable/10958
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1971 Jun 01. 68(6), 1121-1124.
Externí odkaz:
https://www.jstor.org/stable/60286
Publikováno v:
Indonesian Journal of Anesthesiology and Reanimation; Vol. 2 No. 2 (2020): Indonesian Journal of Anesthesiology and Reanimation; 38-46
Introduction: The use of ketamine and tramadol as postoperative analgesics for pediatric are still relatively rare, especially orally administrated. As an analgesic, ketamine blocks the NMDA receptor, the main excitatory transmitter in CNS; whereas t
Publikováno v:
'Nature Communications ', vol: 12, pages: 2199-1-2199-12 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Norepinephrine is a biogenic amine neurotransmitter that has widespread effects on alertness, arousal and pain sensation. Consequently, blockers of norepinephrine uptake have served as vital tools to treat depression and chronic pain. Here, we employ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3b14f38e7022e3ec6d644b991edea4
https://doi.org/10.1101/2020.04.30.070219
https://doi.org/10.1101/2020.04.30.070219
Publikováno v:
Bone Reports, Vol 9, Iss, Pp 188-198 (2018)
Bone Reports
Bone Reports
The sympathetic nervous system is a major efferent pathway through which the central nervous system controls the function of peripheral organs. Genetic and pharmacologic evidence in mice indicated that stimulation of the β2 adrenergic receptor (β2A
Autor:
John E. O'Brien, John D. Power, Michael H. Baumann, Geraldine Dowling, Gary Hessman, Noreen Morris, Pierce V. Kavanagh, Gavin McLaughlin, Simon D. Brandt, Donna Walther, Brian Murphy, Brendan Twamley, John S. Partilla
Publikováno v:
Drug Testing and Analysis. 9:347-357
Misuse of (±)-threo-methylphenidate (methyl-2-phenyl-2-(piperidin-2-yl)acetate; Ritalin®, MPH) has long been acknowledged, but the appearance of MPH analogs in the form of ‘research chemicals’ has only emerged in more recent years. 4-Fluorometh