Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Noreen McBrearty"'
Autor:
Noreen McBrearty, Alla Arzumanyan, Eugene Bichenkov, Salim Merali, Carmen Merali, Mark Feitelson
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 529-538 (2021)
Chronic infection with hepatitis B virus (HBV) is a major risk factor for the development of hepatocellular carcinoma (HCC). The HBV encoded oncoprotein, HBx, alters the expression of host genes and the activity of multiple signal transduction pathwa
Externí odkaz:
https://doaj.org/article/57637a8580564887a2fbb70606014cd3
Autor:
Selwyn J. Hurwitz, Noreen McBrearty, Alla Arzumanyan, Eugene Bichenkov, Sijia Tao, Leda Bassit, Zhe Chen, James J. Kohler, Franck Amblard, Mark A. Feitelson, Raymond F. Schinazi
Publikováno v:
Viruses, Vol 13, Iss 1, p 114 (2021)
While treatment options are available for hepatitis B virus (HBV), there is currently no cure. Anti-HBV nucleoside analogs and interferon-alpha 2b rarely clear HBV covalently closed circular DNA (cccDNA), requiring lifelong treatment. Recently, we id
Externí odkaz:
https://doaj.org/article/74d257cd15f04e9c84764a13e9c822eb
Autor:
Serge Y. Fuchs, Dmitry I. Gabrilovich, Yulia Nefedova, Allison Berger, Gurpanna Saggu, Jose R. Conejo-Garcia, M. Andres Blanco, Daniel P. Beiting, Tara Lee Costich, Noreen McBrearty, Jun Gui, Fangxue Yan, Raghavendra Basavaraja, Jinyang Li, Vivek S. Tomar, Hongru Zhang
Supplementary Tables 1, 2, and 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546bad13fd141f8f1defa7dae784bf9e
https://doi.org/10.1158/2326-6066.22545902
https://doi.org/10.1158/2326-6066.22545902
Autor:
Serge Y. Fuchs, Dmitry I. Gabrilovich, Yulia Nefedova, Allison Berger, Gurpanna Saggu, Jose R. Conejo-Garcia, M. Andres Blanco, Daniel P. Beiting, Tara Lee Costich, Noreen McBrearty, Jun Gui, Fangxue Yan, Raghavendra Basavaraja, Jinyang Li, Vivek S. Tomar, Hongru Zhang
Fragility of regulatory T (Treg) cells manifested by the loss of neuropilin-1 (NRP1) and expression of IFNγ undermines the immune suppressive functions of Treg cells and contributes to the success of immune therapies against cancers. Intratumoral Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b2160ed088e90c87fe5fb79aaab1bd
https://doi.org/10.1158/2326-6066.c.6551048.v1
https://doi.org/10.1158/2326-6066.c.6551048.v1
Autor:
Serge Y. Fuchs, Dmitry I. Gabrilovich, Yulia Nefedova, Allison Berger, Gurpanna Saggu, Jose R. Conejo-Garcia, M. Andres Blanco, Daniel P. Beiting, Tara Lee Costich, Noreen McBrearty, Jun Gui, Fangxue Yan, Raghavendra Basavaraja, Jinyang Li, Vivek S. Tomar, Hongru Zhang
Supplementary Figure from Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569162bd4707629449e8049aabe81276
https://doi.org/10.1158/2326-6066.22545905
https://doi.org/10.1158/2326-6066.22545905
Autor:
Serge Y. Fuchs, Dmitry I. Gabrilovich, Yulia Nefedova, Allison Berger, Gurpanna Saggu, Jose R. Conejo-Garcia, M. Andres Blanco, Daniel P. Beiting, Tara Lee Costich, Noreen McBrearty, Jun Gui, Fangxue Yan, Raghavendra Basavaraja, Jinyang Li, Vivek S. Tomar, Hongru Zhang
Supplementary Data from Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ebcb7cdb23f17e6ced8aaf06d2b8c0
https://doi.org/10.1158/2326-6066.22545911.v1
https://doi.org/10.1158/2326-6066.22545911.v1
Autor:
Serge Y. Fuchs, Hallgeir Rui, Ben Z. Stanger, Anil K. Rustgi, Edna Cukierman, Igor Astsaturov, Jason R. Pitarresi, Jinyang Li, Hongru Zhang, Zhen Lu, Pengfei Yu, Anne Devine, Clarice Pavlak, Charles-Antoine Assenmacher, Enrico Radaelli, Amy R. Peck, Farima Zahedi, Jinyun Chen, Christina Cho, Noreen McBrearty
S1. Frequency of Pan-IN lesion types in KC versus KCC mice. S2. Re-expression of Ch25h in PDAC cell lines. S3. Presence of exogenous lipids diminishes effect of Ch25h re-expression in PDAC. S4. Re-expression of Ch25h does not affect Ras localization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0145a9bb0bb5a7c5e729d66a5e053b9d
https://doi.org/10.1158/1541-7786.22527420
https://doi.org/10.1158/1541-7786.22527420
Autor:
Serge Y. Fuchs, Hallgeir Rui, Ben Z. Stanger, Anil K. Rustgi, Edna Cukierman, Igor Astsaturov, Jason R. Pitarresi, Jinyang Li, Hongru Zhang, Zhen Lu, Pengfei Yu, Anne Devine, Clarice Pavlak, Charles-Antoine Assenmacher, Enrico Radaelli, Amy R. Peck, Farima Zahedi, Jinyun Chen, Christina Cho, Noreen McBrearty
Supplementary Table 1: List of oligonucleotides used for qPCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a0588093271601580b114136bea60f
https://doi.org/10.1158/1541-7786.22527417.v1
https://doi.org/10.1158/1541-7786.22527417.v1
Autor:
Serge Y. Fuchs, Hallgeir Rui, Ben Z. Stanger, Anil K. Rustgi, Edna Cukierman, Igor Astsaturov, Jason R. Pitarresi, Jinyang Li, Hongru Zhang, Zhen Lu, Pengfei Yu, Anne Devine, Clarice Pavlak, Charles-Antoine Assenmacher, Enrico Radaelli, Amy R. Peck, Farima Zahedi, Jinyun Chen, Christina Cho, Noreen McBrearty
Cholesterol dependence is an essential characteristic of pancreatic ductal adenocarcinoma (PDAC). Cholesterol 25-hydroxylase (CH25H) catalyzes monooxygenation of cholesterol into 25-hydroxycholesterol, which is implicated in inhibiting cholesterol bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::390cea891da13dd48b6368c1d16dc31b
https://doi.org/10.1158/1541-7786.c.6545421.v1
https://doi.org/10.1158/1541-7786.c.6545421.v1
Autor:
Hongru Zhang, Vivek S. Tomar, Jinyang Li, Raghavendra Basavaraja, Fangxue Yan, Jun Gui, Noreen McBrearty, Tara Lee Costich, Daniel P. Beiting, M. Andres Blanco, Jose R. Conejo-Garcia, Gurpanna Saggu, Allison Berger, Yulia Nefedova, Dmitry I. Gabrilovich, Serge Y. Fuchs
Publikováno v:
Cancer Immunol Res
Fragility of regulatory T (Treg) cells manifested by the loss of neuropilin-1 (NRP1) and expression of IFNγ undermines the immune suppressive functions of Treg cells and contributes to the success of immune therapies against cancers. Intratumoral Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20922e070b73ffc8481106619e1a90b
https://europepmc.org/articles/PMC9722544/
https://europepmc.org/articles/PMC9722544/