Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Noreen Eder"'
Autor:
Noreen Eder, Federico Roncaroli, Marie-Charlotte Domart, Stuart Horswell, Felipe Andreiuolo, Helen R. Flynn, Andre T. Lopes, Suzanne Claxton, John-Paul Kilday, Lucy Collinson, Jun-Hao Mao, Torsten Pietsch, Barry Thompson, Ambrosius P. Snijders, Sila K. Ultanir
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
YAP1 gene fusions are found in subgroups of paediatric ependymomas. Here the authors show that YAP1 activation in NeuroD6 positive neuronal precursor cells can induce ependymoma-like tumours in mice.
Externí odkaz:
https://doaj.org/article/e28a2ae9a5014ff08a75f121065097ec
Autor:
Roman O Fedoryshchak, Magdalena Přechová, Abbey M Butler, Rebecca Lee, Nicola O'Reilly, Helen R Flynn, Ambrosius P Snijders, Noreen Eder, Sila Ultanir, Stephane Mouilleron, Richard Treisman
Publikováno v:
eLife, Vol 9 (2020)
PPP-family phosphatases such as PP1 have little intrinsic specificity. Cofactors can target PP1 to substrates or subcellular locations, but it remains unclear how they might confer sequence-specificity on PP1. The cytoskeletal regulator Phactr1 is a
Externí odkaz:
https://doaj.org/article/d44fd2f8800b402e9a011331fbee17e9
Autor:
Noreen Eder, Federico Roncaroli, Marie-Charlotte Domart, Stuart Horswell, Felipe Andreiuolo, Helen R. Flynn, Andre T. Lopes, Suzanne Claxton, John-Paul Kilday, Lucy Collinson, Jun-Hao Mao, Torsten Pietsch, Barry Thompson, Ambrosius P. Snijders, Sila K. Ultanir
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/f83deb736d144f31b885a2a605fb1713
Autor:
Christoph Steurer, Noreen Eder, Sarah Kerschbaum, Christina Wegrostek, Stefan Gabriel, Natalia Pardo, Viktoria Ortner, Thomas Czerny, Elisabeth Riegel
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209077 (2018)
The heat shock response (HSR) pathway is a highly conserved cellular stress response and mediated by its master regulator HSF1. Activation of the pathway results in the expression of chaperone proteins (heat shock proteins; HSP) to maintain protein h
Externí odkaz:
https://doaj.org/article/6c2e1aaf3e3a4e9f863b9f468e423df1
Autor:
Marie-Charlotte Dolmart, John-Paul Kilday, Noreen Eder, Suzanne Claxton, Ambrosius P. Snijders, Junhao Mao, Helen R. Flynn, Torsten Pietsch, Felipe Andreiuolo, Stuart Horswell, Sila K. Ultanir, Federico Roncaroli, Lucy M. Collinson, André T. Lopes, Barry J. Thompson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Eder, N, Roncaroli, F, Dolmart, M-C, Horswell, S, Andreiuolo, F, Flynn, H R, Lopes, A T, Claxton, S, Kilday, J-P, Collinson, L, Mao, J-H, Pietsch, T, Thompson, B, Snijders, A P & Ultanir, S K 2020, ' YAP1/TAZ drives ependymoma-like tumour formation in mice ', Nature Communications, vol. 11, no. 1, pp. 2380 . https://doi.org/10.1038/s41467-020-16167-y
Nature Communications
Eder, N, Roncaroli, F, Dolmart, M-C, Horswell, S, Andreiuolo, F, Flynn, H R, Lopes, A T, Claxton, S, Kilday, J-P, Collinson, L, Mao, J-H, Pietsch, T, Thompson, B, Snijders, A P & Ultanir, S K 2020, ' YAP1/TAZ drives ependymoma-like tumour formation in mice ', Nature Communications, vol. 11, no. 1, pp. 2380 . https://doi.org/10.1038/s41467-020-16167-y
YAP1 gene fusions have been observed in a subset of paediatric ependymomas. Here we show that, ectopic expression of active nuclear YAP1 (nlsYAP5SA) in ventricular zone neural progenitor cells using conditionally-induced NEX/NeuroD6-Cre is sufficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26c7a0a824fe2ef09f34161b30ba697
https://doaj.org/article/e28a2ae9a5014ff08a75f121065097ec
https://doaj.org/article/e28a2ae9a5014ff08a75f121065097ec
Autor:
Flavia Roșianu, Simeon R Mihaylov, Noreen Eder, Antonie Martiniuc, Suzanne Claxton, Helen R Flynn, Shamsinar Jalal, Marie-Charlotte Domart, Lucy Collinson, Mark Skehel, Ambrosius P Snijders, Matthias Krause, Sharon A Tooze, Sila K Ultanir
SummaryAutophagy is essential for neuronal development and its deregulation contributes to neurodegenerative diseases. NDR1 and NDR2 are highly conserved kinases implicated in neuronal development, mitochondrial health and autophagy, but how they aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfc689f2499ededaeb47d6c7c1d0bc3d
https://doi.org/10.1101/2022.03.28.486054
https://doi.org/10.1101/2022.03.28.486054
Autor:
Flavia Roşianu, Simeon R Mihaylov, Noreen Eder, Antonie Martiniuc, Suzanne Claxton, Helen R Flynn, Shamsinar Jalal, Marie-Charlotte Domart, Lucy Collinson, Mark Skehel, Ambrosius P Snijders, Matthias Krause, Sharon A Tooze, Sila K Ultanir
Autophagy is essential for neuronal development and its deregulation contributes to neurodegenerative diseases. NDR1 and NDR2 are highly conserved kinases, implicated in neuronal development, mitochondrial health and autophagy, but how they affect ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436caf86cc5af61e7a64129158b2e15c
Autor:
Flavia Rosianu, Antonie Martiniuc, Ambrosius P. Snijders, Marie-Charlotte Domart, Sharon A. Tooze, Suzanne Claxton, Lucy M. Collinson, Matthias Krause, Helen R. Flynn, Noreen Eder, Simeon R. Mihaylov, Sila K. Ultanir
Publikováno v:
SSRN Electronic Journal.
NDR kinases NDR1 and NDR2 are highly conserved regulators of neuronal differentiation that are also implicated in mitochondrial health and autophagy. The roles of NDR1/2 in mammalian brain homeostasis in vivo have not been explored. Using constitutiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e73cce8da1e56d62585278e7d6431ad4
https://doi.org/10.2139/ssrn.3854500
https://doi.org/10.2139/ssrn.3854500
Autor:
Suzanne Claxton, Federico Roncaroli, Barry J. Thompson, Helen R. Flynn, Torsten Pietsch, Sila K. Ultanir, Felipe Andreiuolo, Ambrosius P. Snijders, Marie-Charlotte Domart, Stuart Horswell, Lucy M. Collinson, André T. Lopes, Junhao Mao, Noreen Eder, John-Paul Kilday
Publikováno v:
Eder, N, Roncaroli, F, Domart, M-C, Horswell, S, Andreiuolo, F, Flynn, H R, Lopes, A T, Claxton, S, Kilday, J-P, Collinson, L, Mao, J-H, Pietsch, T, Thompson, B, Snijders, A P & Ultanir, S K 2020, ' Author Correction : YAP1/TAZ drives ependymoma-like tumour formation in mice ', Nature Communications, vol. 11, no. 1, pp. 4934 . https://doi.org/10.1038/s41467-020-18851-5
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
YAP1 gene fusions have been observed in a subset of paediatric ependymomas. Here we show that, ectopic expression of active nuclear YAP1 (nlsYAP5SA) in ventricular zone neural progenitor cells using conditionally-induced NEX/NeuroD6-Cre is sufficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455b0bd5346b8445f7e33b0b535fffcc
https://www.research.manchester.ac.uk/portal/en/publications/author-correction(9a973137-d785-4d3a-86e1-4e4b94ac09fc).html
https://www.research.manchester.ac.uk/portal/en/publications/author-correction(9a973137-d785-4d3a-86e1-4e4b94ac09fc).html
Author response: Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme
Autor:
R. Fedoryshchak, A.M. Butler, Sila K. Ultanir, Magdalena Přechová, Rebecca Lee, Ambrosius P. Snijders, Richard Treisman, Nicola O’Reilly, Helen R. Flynn, Noreen Eder, Stephane Mouilleron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f027ab0ad7109d990f4c7e97f6d9f762
https://doi.org/10.7554/elife.61509.sa2
https://doi.org/10.7554/elife.61509.sa2